计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
有货
为什么选择此级别
Moligand™,天然 级 提供 ≥95%(HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
2-8°C储存。低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 54 篇同行评审文献引用。
概述
Capsaicin acts as an agonist at the VR1 (TRPV1) receptor, a ligand-gated non-selective cation channel. It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons. Capsaicin also Inhibits NFκB activation by TNF and reversibly inhibits platelet aggregation. Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection.A TRPV1 receptor agonist； A TRPV1 receptor agonist
规格
别名
辣椒素
英文别名
CAPSAICIN (USP-RS) | 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)- | N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide | NCGC00017337-02 | N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide | (6E)-N-{[4-hydroxy-3-(methylox
规格或纯度
Moligand™, 天然, ≥95%(HPLC), from Capsicum sp.
英文名称
Capsaicin
生化机理
原型香草类受体激动剂（大鼠和人类VR1受体的pEC50值分别为7.97和7.10）。激发原发传入感觉神经元的子集，具有随后的抗伤害感受和消炎作用。可逆地抑制血小板聚集。
应用
A TRPV1 receptor agonist
储存条件
2-8°C储存
运输条件
低温运输
纯度
≥95%(HPLC)
名称和识别符
PubChem SID
EC号
206-969-8
分子类型
小分子
IUPAC Name
(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
INCHI
1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
InChi Key
YKPUWZUDDOIDPM-SOFGYWHQSA-N
Smiles
CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Isomeric SMILES
CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
UN Number
分子量
305.41
Beilstein号
2816484
Reaxy-Rn
2816483
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2816483&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 苯类化合物 |
| 类（Class) | 酚类 |
| 亚类（Subclass） | 甲氧基苯酚 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 甲氧基苯酚 |
| 其他上位类（Alternative Parents） | 苯氧基化合物 甲氧基苯 茴香醚 烷基芳基醚 1-羟基-2-未取代苯类化合物 N-酰胺 仲羧酸酰胺 有机光子化合物 有机氮化合物 有机氧化物 碳氢化合物衍生物 羰基化合物 |
| 分子骨架（Molecular Framework) | 芳香族同单环化合物 |
| 取代基（Substituents） | 1-羟基-2-未取代苯环化合物 - 芳基醚 - 茴香醚 - 芳香族同单环化合物 - 羰基 - 羧酰胺基 - 羧酸衍生物 - 乙醚 - 脂肪酰基 - 脂肪酰胺 - 烃衍生物 - 甲氧基苯 - 甲氧基苯酚 - 单环苯基基团 - N-酰胺基胺 - 有机硝基化合物 - 有机氧化物 - 有机氧化合物 - 有机氮化合物 - 有机氧化合物 - 有机氮化合物 - 苯酚醚 - 苯氧基化合物 - 醛基 |
| 描述（Description） | 该化合物属于有机化合物中的甲氧基酚类。这类化合物在酚基团的苯环上连接有甲氧基。 |
| 外部描述符（External Descriptors） | Capsaicinoids and derivatives |
三维结构
交互式化学结构模型
产品属性
| ALogP | 3.6 |
|---|
关联靶点（人）
CFTR
Tclin
囊性纤维化跨膜传导调节器(Cystic fibrosis transmembrane conductance regulator)
(0 活性数据)
CYP2C9
Tchem
细胞色素 P450 2C9(Cytochrome P450 2C9)
(0 活性数据)
KCNA7
Tclin
钾电压门控通道亚家族 A 成员 7(Potassium voltage-gated channel subfamily A member 7)
(1 活性数据)
KCNC1
Tclin
钾电压门控通道亚家族 C 成员 1(Potassium voltage-gated channel subfamily C member 1)
(1 活性数据)
TRPV1
Tclin
瞬时受体电位阳离子通道亚家族V成员1(Transient receptor potential cation channel subfamily V member 1)
(23 活性数据)
KCNA2
Tclin
钾电压门控通道亚家族 A 成员 2(Potassium voltage-gated channel subfamily A member 2)
(1 活性数据)
KCNA1
Tclin
钾电压门控通道亚家族 A 成员 1(Potassium voltage-gated channel subfamily A member 1)
(1 活性数据)
PDE5A
Tclin
Phosphodiesterase 5A
(5113 活性数据)
EGFR
Tclin
Epidermal growth factor receptor erbB1
(33727 活性数据)
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
HMGCR
Tclin
HMG-CoA reductase
(2475 活性数据)
NR3C1
Tclin
Glucocorticoid receptor
(14987 活性数据)
INSR
Tclin
Insulin receptor
(5558 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
ADRB2
Tclin
Beta-2 adrenergic receptor
(11824 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
ADRB1
Tclin
Beta-1 adrenergic receptor
(6630 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
ALOX5
Tclin
Arachidonate 5-lipoxygenase
(6568 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
ACE
Tclin
Angiotensin-converting enzyme
(1423 活性数据)
DRD2
Tclin
Dopamine D2 receptor
(23596 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
CNR1
Tclin
Cannabinoid CB1 receptor
(20913 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
DRD4
Tchem
Dopamine D4 receptor
(7907 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
HRH2
Tclin
Histamine H2 receptor
(5428 活性数据)
ADRA1D
Tclin
Alpha-1d adrenergic receptor
(4171 活性数据)
HTR1B
Tclin
Serotonin 1b (5-HT1b) receptor
(2801 活性数据)
HTR2A
Tclin
Serotonin 2a (5-HT2a) receptor
(14758 活性数据)
HTR2C
Tclin
Serotonin 2c (5-HT2c) receptor
(11471 活性数据)
AVPR2
Tclin
Vasopressin V2 receptor
(2912 活性数据)
ADORA1
Tclin
Adenosine A1 receptor
(17603 活性数据)
AGTR1
Tclin
Type-1 angiotensin II receptor
(5176 活性数据)
CALCR
Tclin
Calcitonin receptor
(2215 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
PTGS2
Tclin
Cyclooxygenase-2
(13999 活性数据)
HRH1
Tclin
Histamine H1 receptor
(7573 活性数据)
ADRA1B
Tclin
Alpha-1b adrenergic receptor
(2912 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
PPARG
Tclin
Peroxisome proliferator-activated receptor gamma
(15191 活性数据)
AVPR1A
Tclin
Vasopressin V1a receptor
(5412 活性数据)
OPRD1
Tclin
Delta opioid receptor
(15096 活性数据)
OPRK1
Tclin
Kappa opioid receptor
(16155 活性数据)
HTR3A
Tclin
Serotonin 3a (5-HT3a) receptor
(3366 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
GRIN1
Tclin
Glutamate (NMDA) receptor subunit zeta 1
(122 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
关联靶点（其它种属）
Agtr2
Angiotensin II type 2 (AT-2) receptor (803 活性数据)
Mc4r
Melanocortin receptor 4 (1205 活性数据)
Ltc4s
Leukotriene C4 synthase (1 活性数据)
Sigmar1
Sigma opioid receptor (160 活性数据)
Ttr
Transthyretin (14 活性数据)
Npy1r
Neuropeptide Y receptor type 1 (8 活性数据)
Cckar
Cholecystokinin A receptor (90 活性数据)
Pde4d
Phosphodiesterase 4D (4 活性数据)
Nos2
Nitric oxide synthase, inducible (3573 活性数据)
Mapk1
MAP kinase ERK2 (650 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
Mmp9
Matrix metalloproteinase 9 (38 活性数据)
MT-ND1
NADH-ubiquinone oxidoreductase chain 1 (124 活性数据)
Staphylococcus aureus (210822 活性数据)
Escherichia coli (133304 活性数据)
Bacillus subtilis (32866 活性数据)
Plasmodium falciparum (966862 活性数据)
Cavia porcellus (23802 活性数据)
Mus musculus (284745 活性数据)
Rattus norvegicus (775804 活性数据)
C6 (2371 活性数据)
B16-F10 (4610 活性数据)
norA
Quinolone resistance protein norA (2171 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
Trpa1
Transient receptor potential cation channel subfamily A member 1 (1003 活性数据)
Lipe
Hormone-sensitive lipase (209 活性数据)
Trpm8
Transient receptor potential cation channel subfamily M member 8 (889 活性数据)
pfk
6-phospho-1-fructokinase (7870 活性数据)
BCHE
Cholinesterase (8742 活性数据)
Mapt
Microtubule-associated protein tau (6 活性数据)
Nfe2l2
Nuclear factor erythroid 2-related factor 2 (214 活性数据)
Rorc
Nuclear receptor ROR-gamma (89407 活性数据)
Impa1
Inositol monophosphatase 1 (16203 活性数据)
ffp
4'-phosphopantetheinyl transferase ffp (24982 活性数据)
Trpv1
Transient receptor potential cation channel subfamily V member 1 (45 活性数据)
Cell membrane (1233 活性数据)
Schistocerca americana (16 活性数据)
Diaprepes abbreviatus (13 活性数据)
Glra2
Glycine receptor (1745 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
溶解性
溶于DMSO, 最高浓度 (mg/mL): 15.27, 最高浓度(mM): 50；溶于ethanol, 最高浓度 (mg/mL): 15.27, 最高浓度(mM): 50
密度
1.041
闪点(℉)
235.4 °F
闪点(℃)
113℃
熔点
65°C
分子量
305.400 g/mol
XLogP3
3.600
氢键供体数Hydrogen Bond Donor Count
2
氢键受体数Hydrogen Bond Acceptor Count
3
可旋转键计数Rotatable Bond Count
9
精确质量Exact Mass
305.199 Da
单同位素质量Monoisotopic Mass
305.199 Da
拓扑极表面积Topological Polar Surface Area
58.600 Ų
重原子数Heavy Atom Count
22
形式电荷Formal Charge
0
复杂度Complexity
341.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
0
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
1
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
1
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
信号词
危险
危险声明
H301: 吞咽会中毒
H315: 引起皮肤刺激
H317: 可能引起皮肤过敏反应
H318: 造成严重的眼睛损伤
H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
H335: 可能引起呼吸道刺激
预防措施声明
P264: 处理后要彻底洗手。
P270: 使用本产品时，请勿进食、饮水或吸烟。
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P321: 特殊处理（请参阅此标签上的...）。
P330: 漱口
P302+P352: 如皮肤沾染：用水充分清洗。
P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。
P405: 密闭存放
P501: 将内容物/容器处理到。。。
P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。
P301+P316: 如果吞咽：立即寻求紧急医疗救助。
P301+P317: 如果被吞咽：请寻求医疗帮助。
P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。
P317: 寻求紧急医疗救助。
P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany
3
RTECS
RA8530000
Merck Index
1768
个人防护装备
Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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| 批号(Lot Number) | 证书类型 | 货号 |
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分析证书 | C107693 |
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分析证书 | C107693 |
| C2505633 |
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| I2414465 |
分析证书 | C107693 |
| I2414466 |
分析证书 | C107693 |
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分析证书 | C107693 |
| D2314694 |
分析证书 | C107693 |
| D2314681 |
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此产品的引用文献
引用文献
| 1. Yamei Ma, Zhen Zhang, Shengchao Gao, Yue Zhan, Zihao Wei, Ying Liu. (2023) The efficient Congo red decolorization coupled with electricity generation via G. sulfurreducens based on microbial fuel cells. Journal of Environmental Chemical Engineering, [10.1016/j.jece.2023.111296] |
| 2. Yiding ZHAO, Xiaoning YAN, Shanshan JIANG, Yong LIU, Chun DONG, Huiyan CHI, Chaoyi MAO. (2023) Zhenxin Anshen formula ameliorates atopic der-matitis-like skin dysfunction in mice and regulation of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 in Neural pathways.. Journal of Traditional Chinese Medicine, 43 (5): (887-896). [PMID:37679976] [10.19852/j.cnki.jtcm.20230802.003] |
| 3. Xing Yan, Ming-Jun Zhu. (2023) Enhanced bioelectricity generation in thermophilic microbial fuel cell with lignocellulose as an electron donor by resazurin-mediated electron transfer. BIORESOURCE TECHNOLOGY, [PMID:37722540] [10.1016/j.biortech.2023.129764] |
| 4. Xu Rui-Qi, Ma Ling, Chen Timson, Zhang Wei-Xiong, Chang Kuan, Wang Jing. (2023) Sophorolipid inhibits histamine-induced itch by decreasing PLC/IP3R signaling pathway activation and modulating TRPV1 activity. Scientific Reports, 13 (1): (1-13). [PMID:37198299] [10.1038/s41598-023-35158-9] |
| 5. Lingling Qin, Jie Cao, Dan Lin, Shihao Xu, Yucheng Li, Changlong Jiang. (2023) A Strecker-like reaction triggering fluorescent sensing platform for enzyme-free and visual quantitative monitoring of carbamates. CHEMICAL ENGINEERING JOURNAL, [10.1016/j.cej.2023.142550] |
| 6. Yiwen Zhu, Xiang Li, Shui Jiang, Yin Zhang, Lihua Zhang, Yuan Liu. (2023) Multi-dimensional pungency and sensory profiles of powder and oil of seven chili peppers based on descriptive analysis and Scoville heat units. FOOD CHEMISTRY, [PMID:36681025] [10.1016/j.foodchem.2023.135488] |
| 7. Sijun Wu, Long Wang, Guoming Zhou, Chao Liu, Zhongrui Ji, Zheng Li, Wenlong Li. (2022) Strategies for the content determination of capsaicin and the identification of adulterated pepper powder using a hand-held near-infrared spectrometer. FOOD RESEARCH INTERNATIONAL, [PMID:36596130] [10.1016/j.foodres.2022.112192] |
| 8. Yun Ning, Lu Chaoqun, Sun Tian, Xu Baocai, Song Yushen, Zong Zibing, Chen Kangwen, Huang Ganhui, Chen Xingguang, Gu Qianhui. (2022) High Sensitivity Detection of Capsaicin in Red Pepper Oil Based on Reduced Graphene Oxide Enhanced by β-Cyclodextrin. Food Analytical Methods, 16 (2): (318-329). [10.1007/s12161-022-02415-y] |
| 9. Li Junkui, Zuo Min, Zhang Wen, Zou Xiaobo, Sun Zongbao. (2022) Diazo Coupling-Based Ultrasensitive SERS Detection of Capsaicin and Its Application in Identifying Gutter Oil. Food Analytical Methods, 15 (12): (3468-3478). [10.1007/s12161-022-02372-6] |
| 10. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu. (2022) The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis. CHEMISTRY & BIODIVERSITY, 19 (5): (e202200177). [PMID:35426465] [10.1002/cbdv.202200177] |
| 11. Mengqing Xu, Jin Zhang, Yongli Mu, Mohamed Frahat Foda, Heyou Han. (2022) Activation of TRPV1 by capsaicin-loaded CaCO3 nanoparticle for tumor-specific therapy. BIOMATERIALS, [PMID:35436739] [10.1016/j.biomaterials.2022.121520] |
| 12. Fang Xiao, Duan Rongshuai. (2022) Highly Sensitive Capsaicin Electrochemical Sensor Based on Bimetallic Metal-Organic Framework Nanocage. Frontiers in Chemistry, [PMID:35242739] [10.3389/fchem.2022.822619] |
| 13. Yan Jia, Xie Shujie, Xia Qin, Li Xiang, Chen Shuhuai, Shen Jia. (2022) Engineering of combination drug delivery of pH/reduction response potential nanocarrier for the treatment of liver cancer. Applied Nanoscience, 12 (5): (1545-1556). [10.1007/s13204-021-02312-6] |
| 14. Zi Ye, Zhixun Shang, Shiyao Zhang, Meiqi Li, Xuetin Zhang, Hongbing Ren, Xiaosong Hu, Junjie Yi. (2022) Dynamic analysis of flavor properties and microbial communities in Chinese pickled chili pepper (Capsicum frutescens L.): A typical industrial-scale natural fermentation process. FOOD RESEARCH INTERNATIONAL, [PMID:35227474] [10.1016/j.foodres.2022.110952] |
| 15. Xinghao Liu, Zhaoguang Yang, Wenxiu Zhu, Ying Yang, Haipu Li. (2021) Catalytic ozonation of chloramphenicol with manganese-copper oxides/maghemite in solution: Empirical kinetics model, degradation pathway, catalytic mechanism, and antibacterial activity. JOURNAL OF ENVIRONMENTAL MANAGEMENT, [PMID:34735833] [10.1016/j.jenvman.2021.114043] |
| 16. Yuan Yin, Dong Fei-Xue, Liu Xu, Xiao Hong-Bin, Zhou Zhong-Guang. (2021) Liquid Chromatograph-Mass Spectrometry-Based Non-targeted Metabolomics Discovery of Potential Endogenous Biomarkers Associated With Prostatitis Rats to Reveal the Effects of Magnoflorine. Frontiers in Pharmacology, [PMID:34790120] [10.3389/fphar.2021.741378] |
| 17. Di Wu, Ran Duan, Lan Tang, Dian Zhou, Zhen Zeng, Wen Wu, Jie Hu, Qiaomei Sun. (2021) In-vitro binding analysis and inhibitory effect of capsaicin on lipase. LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2021.112674] |
| 18. Zi Ye, Zhixun Shang, Meiqi Li, Yonghan Qu, Hongjin Long, Junjie Yi. (2020) Evaluation of the physiochemical and aromatic qualities of pickled Chinese pepper (Paojiao) and their influence on consumer acceptability by using targeted and untargeted multivariate approaches. FOOD RESEARCH INTERNATIONAL, [PMID:33233164] [10.1016/j.foodres.2020.109535] |
| 19. Zhigang Liu, Xianli Wang, Jie Chen, Jimin Gao, Shihua Yu, Xiuguo Wang. (2020) Three-template magnetic molecular imprinted polymer for the rapid separation and specific recognition of illegal cooking oil markers. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2020.105052] |
| 20. Fuchao Zhan, Shuang Ding, Wenya Xie, Xiao Zhu, Jiangnan Hu, Jun Gao, Bin Li, Yijie Chen. (2020) Towards understanding the interaction of β-lactoglobulin with capsaicin: Multi-spectroscopic, thermodynamic, molecular docking and molecular dynamics simulation approaches. FOOD HYDROCOLLOIDS, [10.1016/j.foodhyd.2020.105767] |
| 21. Jiayi Zhao, Feng Wei, Weili Xu, Xiaojun Han. (2020) Enhanced antibacterial performance of gelatin/chitosan film containing capsaicin loaded MOFs for food packaging. APPLIED SURFACE SCIENCE, [10.1016/j.apsusc.2020.145418] |
| 22. Mingming Zhu, Xi Yu, Zongmei Zheng, Jiaming Huang, Xuepan Yang, Hongfei Shi. (2019) Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway. PHYTOTHERAPY RESEARCH, 34 (4): (817-824). [PMID:31782192] [10.1002/ptr.6563] |
| 23. Xiang Shen, Peng Liu, Shubiao Xia, Jianjun Liu, Rui Wang, Hua Zhao, Qiuju Liu, Jiao Xu, Fan Wang. (2019) Anti-Fouling and Anti-Bacterial Modification of Poly(vinylidene fluoride) Membrane by Blending with the Capsaicin-Based Copolymer. Polymers, 11 (2): (323). [PMID:30960307] [10.3390/polym11020323] |
| 24. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [10.1080/09540105.2018.1490394] |
| 25. Zhigang Liu, Shihua Yu, Shuping Xu, Bing Zhao, Weiqing Xu. (2017) Ultrasensitive Detection of Capsaicin in Oil for Fast Identification of Illegal Cooking Oil by SERRS. ACS Omega, [PMID:31457378] [10.1021/acsomega.7b01457] |
| 26. Wang Yan, Huang Bin-Bin, Dai Wan-Lin, Xu Bin, Wu Tian-Liang, Ye Jia-Ping, Ye Jian-Shan. (2017) Sensitive Electrochemical Capsaicin Sensor Based on a Screen Printed Electrode Modified with Poly(sodium 4-styrenesulfonate) Functionalized Graphite. ANALYTICAL SCIENCES, 33 (7): (793-799). [PMID:28690256] [10.2116/analsci.33.793] |
| 27. Yan Wang, Binbin Huang, Wanlin Dai, Jianshan Ye, Bin Xu. (2016) Sensitive determination of capsaicin on Ag/Ag2O nanoparticles/reduced graphene oxide modified screen-printed electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, [10.1016/j.jelechem.2016.06.031] |
| 28. Ping Qi, Zhihao Lin, Jiaxu Li, ChengLong Wang, WeiWei Meng, Hong Hong, Xuewu Zhang. (2014) Development of a rapid, simple and sensitive HPLC-FLD method for determination of rhodamine B in chili-containing products. FOOD CHEMISTRY, [PMID:24996311] [10.1016/j.foodchem.2014.05.036] |
| 29. Jiang Mingzhou, Zhu Zhidong, Zhou Ziyu, Yan Zhiqiang, Huang Kai, Jiang Rongrong, Fan Xi, Jieensi Milayi, Pang Liewen, Wang Yiqing, Sun Xiaotian. (2024) A temperature-ultrasound sensitive nanoparticle delivery system for exploring central neuroinflammation mechanism in stroke-heart syndrome. JOURNAL OF NANOBIOTECHNOLOGY, 22 (1): (1-19). [PMID:39506743] [10.1186/s12951-024-02961-z] |
| 30. Meitong Liu, Jiakang Guo, Jing Lu, Yuelin Chen, Xuming Deng, Shengzhuo Zhang, Shuang Guan. (2024) Capsaicin alleviates acute alcohol-induced pyroptosis by activating ESCRT-III-dependent cell membrane repair in hepatocytes. Food & Function, [PMID:39036891] [10.1039/D4FO00806E] |
| 31. Sun Hui, Wang ZiTong, Tu BingHua, Shao ZiChen, Li YiDan, Han Di, Jiang YinJie, Zhang Peng, Zhang WeiChang, Wu YunYan, Wu XiaoMing, Liu Chi-Ming. (2024) Capsaicin reduces blood glucose and prevents prostate growth by regulating androgen, RAGE/IGF-1/Akt, TGF-β/Smad signalling pathway and reversing epithelial-mesenchymal transition in streptozotocin-induced diabetic mice. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, [PMID:38700794] [10.1007/s00210-024-03092-w] |
| 32. Jiamiao Hu, Zhongjing Lin, Yang Yang, Mark Christian, Shiyang Li, Baodong Zheng, Bee K. Tan, Shaoling Lin. (2024) Preconceptional capsaicin intervention mitigates negative effects of paternal obesity on metabolic characteristics in male offspring upon high-fat diet challenge. Journal of Functional Foods, [10.1016/j.jff.2024.106137] |
| 33. Zhixu Zhang, Lu Zeng, Weiming Zhang, Hongbin Ren, Li Liu, Zhuqing Zhang, Xuexiao Zou, Dan Qin, Lijun Ou. (2024) Process Adaptability Appraisal of Fermented Chopped Chili Pepper Made from Fresh Chili Peppers of Different Varieties. Agronomy-Basel, 14 (8): (1833). [10.3390/agronomy14081833] |
| 34. Di Yuan, Yuting Yuan, Liangxiao Zhang, Fei Ma, Peiwu Li. (2024) Rapid, efficient, and accurate determination of aflatoxins and capsaicinoids in vegetable oils by immunomagnetic sorbents coupled with UHPLC–MS/MS. Food Frontiers, 5 (3): (1004-1013). [10.1002/fft2.382] |
| 35. Tingting Zhou, Zhiwei Wang, Xiaowang Lv, Mengting Guo, Ning Zhang, Liangju Liu, Li Geng, Jing Shao, Ka Zhang, Mengru Gao, Aiqin Mao, Yifei Zhu, Fan Yu, Lei Feng, Xiaoyan Wang, Qixiao Zhai, Wei Chen, Xin Ma. (2025) Targeting gut S. aureofaciens Tü117 serves as a new potential therapeutic intervention for the prevention and treatment of hypertension. Cell Metabolism, [PMID:39908987] [10.1016/j.cmet.2025.01.004] |
| 36. Dingding Li, Beibei Chu, Bo Li, Xiong Wang, Xingguang Chen, Qianhui Gu. (2024) The difference analysis of physicochemical indexes and volatile flavor compounds of chili oil prepared from different varieties of chili pepper. FOOD RESEARCH INTERNATIONAL, [PMID:38945630] [10.1016/j.foodres.2024.114657] |
| 37. Shaojin Ma, Yongyu Li, Yankun Peng, Sen Nie, Xue Bai, Jincheng Zhang. (2025) Simultaneous prediction of pungency and color values of paprika via LED-induced fluorescence. FOOD CHEMISTRY, [PMID:40749487] [10.1016/j.foodchem.2025.145745] |
| 38. Lei Wang, Wen Li, Lin Cao, Huimeng Feng, Yan Liu, Xiao Sun, Jia Cheng, Meiyan Yu, Shougang Chen. (2025) Mesoporous silica reinforced triple-network poly-zwitterionic hydrogel with high-strength and excellent anti-fouling performance. COMPOSITES SCIENCE AND TECHNOLOGY, [10.1016/j.compscitech.2025.111355] |
| 39. Hao Song, Minhao Xie, Hui Xu, Jianhui Liu, AnXiang Su, YiZhou Liu, Ye Wang, Yongjiao Wang, Fei Pei, Wenjian Yang. (2025) Capsaicin regulated lipid metabolism in HepG2 via mitochondrial autophagy PINK1/Parkin pathway. GENE, [PMID:40907586] [10.1016/j.gene.2025.149752] |
| 40. Galong Li, Xin Qiao, Yu Zhao, Dongyan Li, Guigen Zhang, Xiaoli Liu, Fulin Chen, Huaning Wang, Hongbing Lu, Jin Zhou, Changyong Wang, Haiming Fan. (2025) Ferrimagnetic Vortex Nanorings Facilitate Efficient and Safe Deep-Brain Magnetothermal Stimulation in Freely Moving Mice. Exploration, [PMID:41476659] [10.1002/EXP.20240118] |
| 41. Aihua Zhang, Huiyu Wang, Hui Sun, Yue Zhang, Na An, Guangli Yan, Xiangcai Meng, Xijun Wang. (2015) Metabolomics strategy reveals therapeutical assessment of limonin on nonbacterial prostatitis. Food & Function, 6 (11): (3540-3549). [PMID:26302114] [10.1039/C5FO00489F] |
| 42. Hui Sun, Huiyu Wang, Aihua Zhang, Guangli Yan, Yue Zhang, Na An, Xijun Wang. (2015) Berberine Ameliorates Nonbacterial Prostatitis via Multi-Target Metabolic Network Regulation. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 19 (3): (186-195). [PMID:25588034] [10.1089/omi.2014.0112] |
| 43. Dong Liu, Ziqi Zou, Xin Hu, Shiyu Huang, Tongsheng Huang, Jiawei Gu, Weifeng Zhu, Meiying Liu, Shaorong Huang, Xiaoyong Zhang. (2025) Self-assembly of phosphorylated capsaicin and curcumin for treatment of triple-negative breast cancer via combination of chemotherapy and photodynamic therapy. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [10.1016/j.colsurfa.2025.137108] |
| 44. Wenwen Zhang, Songling Li, Hua Tang, Qin Huang, Ping Meng, Hongyu Deng, Ziyi He, Chuan Liu, Ping Liu, Taoying Li, Yongjun Yuan. (2025) Investigation of the flavor profiles on chili rapeseed oil: A study on flavor generation by chili addition and frying oil temperature. LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2025.118064] |
| 45. Huang Xiaowei, Qi Yuqing, Wang Tianxing, Li Zhihua, Zhang Ning, Qin Zhou, Du Liuzi, Zhang Di, Shi Jiyong, Zou Xiaobo. (2025) Development of a nitric oxide sensor for in vitro evaluation of the capsaicin’s anti-inflammatory activity. MICROCHIMICA ACTA, 192 (11): (1-14). [PMID:41083845] [10.1007/s00604-025-07596-x] |
| 46. Haleema Sadia, Wan-Juan Jiang, Pan-Feng Zheng, Yan Zang, Ze-Hua Dong. (2025) A novel PDMS-based coating incorporated with capsaicin and TiO2-modified CNTs: Performance and mechanisms of antifouling and anticorrosion in seawater. PROGRESS IN ORGANIC COATINGS, [10.1016/j.porgcoat.2025.109694] |
| 47. Deng Zhongyuan, Fang Liying, Cheng Lan, Yang Lihong, Zong Ruyi, Ding Qian, Wang Lixiang, Ni Xinzhi, Li Xianchun. (2025) Specialist/generalist divergence: phylogenetic constraints on the correlation between allelochemical tolerance spectra and host ranges of herbivorous insects. JOURNAL OF PEST SCIENCE, 99 (1): (10). [10.1007/s10340-025-02005-x] |
| 48. Yang Yanan, Shao Yuwei, Tian Jun, Wang Yuezhu, Zhu Ye, Pan Siying, Wei Xiali, Jiang Linyan, Wang Xiaoke, Shu Qing. (2026) Acupuncture ameliorates diet-induced obesity via the vagal–GLP-1–ARC circuit: neural mechanism of anorexigenic action. Chinese Medicine, 21 (1): (20). [PMID:41508004] [10.1186/s13020-025-01274-z] |
| 49. Zongmei Huang, Cong-Ting Wu, Jing Li, Lu-Shuang Li. (2026) One-step synthesis of dual-emission carbon dots for ratiometric fluorescence sensing of curcumin in food samples. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2026.116897] |
| 50. Zhen Yang, Huiying Li, Wei Zhao, Yingxia Yu, Yanling Lin, Jianxuan Liu, Xinghu Fan, Moyan Wang, Xin Teng, Zhikai Qiu. (2026) Study on the improvement of cough variant asthma by the Tongfu Zhike formula via the TLR4/MyD88/NF-κB signaling pathway. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:41678939] [10.1016/j.jchromb.2026.124955] |
| 51. Lei Ying, Chen Chao, Zhan Xu, Xie Mingshu, Wang Ying, Li Hao, Zhang Jiale, Liu Ping. (2026) Intestinal pathogens override hunger-driven decision-making via immune regulation of central serotonin signaling in C. elegans. Nature Communications, [PMID:41735301] [10.1038/s41467-026-69924-w] |
| 52. Li Xiao, Lin Lizhou, Zhu Mingrui, Li Xiaolong, Yu Jifeng, Lu Dan, Li Shaoyue, Shen Yuting, Xiong Bing, Zhao Chongke, Zhou Boyang, Yin Haohao, Xu Huixiong, Guan Xin. (2026) Low-intensity focused ultrasound-activated piezoelectric gel bandage for diabetic wound repair and neuropathic pain relief. Nature Communications, [PMID:41857055] [10.1038/s41467-026-70771-y] |
| 53. Mengyun Ouyang, Sheng Cao, Yiji Zhou, Mo Mo, Yuanfang Xu, Qiling Zhang, Yong Zhang, Chao Deng, Feng Guo, Hui Song, Yan Wang, Yiqun Huang, Wenge Li. (2026) Evaluation of gamma irradiation on the microbiological, phytochemicals, and aromatic profiles of sun-bleached preserved pepper (Capsicum annuum L.). FOOD CHEMISTRY, [10.1016/j.foodchem.2026.148833] |
| 54. Galong Li, Dongyan Li, Bin Lan, Yuanyuan Cheng, Hongxia Liang, Wenli Zhang, Xiaopan Xu, Hongbing Lu. (2026) Iron Oxide Nanozyme for Magnetothermal Activation of ER-TRPV1 Enables Efficient Intravesical Therapy of Bladder Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 27 (16): (7475). [PMID:42653475] [10.3390/ijms27167475] |
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