B2420056计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
为什么选择此级别
，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
室温。常规运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 33 篇同行评审文献引用。
概述
应用
甲萘醌用于产生活性氧（ROS），然后进行流式细胞术分析。它还用于微生物评估，例如检测苛求菌。
Gene Information
human ... NQO1(1728)
Application
Menadione has been used for the generation of reactive oxygen species (ROS), followed by flow cytometry analysis. It has also been used in microbiological evaluation, such as to detect fastidious microorganisms.
规格
别名
维生素 K3, 2-甲基-1,4-萘醌
英文别名
Juva-K | Kareon | MENADIONE [MART.] | 2-Methyl-1,4-naftochinon | Menadione (Vitamin K3) 10 microg/mL in Acetonitrile | Methyl-1,4-naphthoquinone | Koaxin | MLS000069420 | Kaynone | Menaquinone O | Menadione (USP:BAN) | 2-methyl-1,4-naphthoquinone, 5 | Kap
规格或纯度
结晶
英文名称
Menadione
生化机理
甲萘醌是一种芳香族多环酮。它是维生素K合成的前体。甲萘醌可转化为甲基萘醌-4（维生素K3的活性代谢产物）。甲萘醌通过无效的氧化还原循环诱导产生活性氧来介导细胞死亡。 甲萘醌（维生素K3）是1,4-萘醌的合成类似物，在2-位有一个甲基。甲萘醌是磷酸酶抑制剂，也是线粒体DNA聚合酶γ (pol γ)抑制剂。甲萘醌可用作氧化损伤（自由基生成剂）诱导剂。
储存条件
室温
运输条件
常规运输
名称和识别符
PubChem SID
EC号
200-372-6
分子类型
小分子
IUPAC Name
2-methylnaphthalene-1,4-dione
INCHI
1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
InChi Key
MJVAVZPDRWSRRC-UHFFFAOYSA-N
Smiles
CC1=CC(=O)C2=CC=CC=C2C1=O
Isomeric SMILES
CC1=CC(=O)C2=CC=CC=C2C1=O
UN Number
分子量
172.18
Beilstein号
1908453
Reaxy-Rn
1908453
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1908453&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 苯类化合物 |
| 类（Class) | 萘 |
| 亚类（Subclass） | 萘醌 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 萘醌 |
| 其他上位类（Alternative Parents） | 醌类 芳基酮 有机氧化物 碳氢化合物衍生物 |
| 分子骨架（Molecular Framework) | 芳香族同多环化合物 |
| 取代基（Substituents） | 芳香族同多环化合物 - 芳基溴化物 - 烃衍生物 - 酮 - 萘醌 - 有机氧化物 - 有机氧化合物 - 有机氧化合物 - 蒽醌 |
| 描述（Description） | 该化合物属于萘醌类有机化合物。这类化合物含有萘羟醌结构单元，其特征为苯环与苯并-1,4-二酮（醌）呈线性共轭。 |
| 外部描述符（External Descriptors） | a vitamin K |
三维结构
交互式化学结构模型
关联靶点（人）
CYP1A2
Tchem
细胞色素 P450 1A2(Cytochrome P450 1A2)
(1 活性数据)
TST
Tchem
硫代硫酸盐硫转移酶(Thiosulfate sulfurtransferase)
(1 活性数据)
MAOB
Tclin
胺氧化酶[含黄素]B(Amine oxidase [flavin-containing] B)
(1 活性数据)
AOX1
Tchem
醛氧化酶(Aldehyde oxidase)
(2 活性数据)
IDO1
Tchem
吲哚胺2,3-双加氧酶1(Indoleamine 2,3-dioxygenase 1)
(2 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
NR3C1
Tclin
Glucocorticoid receptor
(14987 活性数据)
TYMS
Tclin
Thymidylate synthase
(1651 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
ADRB2
Tclin
Beta-2 adrenergic receptor
(11824 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
ADRB1
Tclin
Beta-1 adrenergic receptor
(6630 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
VDR
Tclin
Vitamin D receptor
(26531 活性数据)
DRD2
Tclin
Dopamine D2 receptor
(23596 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
CNR1
Tclin
Cannabinoid CB1 receptor
(20913 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
HRH2
Tclin
Histamine H2 receptor
(5428 活性数据)
MAOB
Tclin
Monoamine oxidase B
(8835 活性数据)
HTR2A
Tclin
Serotonin 2a (5-HT2a) receptor
(14758 活性数据)
HTR2C
Tclin
Serotonin 2c (5-HT2c) receptor
(11471 活性数据)
AVPR2
Tclin
Vasopressin V2 receptor
(2912 活性数据)
ADORA1
Tclin
Adenosine A1 receptor
(17603 活性数据)
AGTR1
Tclin
Type-1 angiotensin II receptor
(5176 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
PTGS2
Tclin
Cyclooxygenase-2
(13999 活性数据)
HRH1
Tclin
Histamine H1 receptor
(7573 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
AVPR1A
Tclin
Vasopressin V1a receptor
(5412 活性数据)
OPRD1
Tclin
Delta opioid receptor
(15096 活性数据)
OPRK1
Tclin
Kappa opioid receptor
(16155 活性数据)
HTR3A
Tclin
Serotonin 3a (5-HT3a) receptor
(3366 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
GRIN1
Tclin
Glutamate (NMDA) receptor subunit zeta 1
(122 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
CACNA1C
Tclin
Voltage-gated L-type calcium channel alpha-1C subunit
(766 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
SLC29A1
Tclin
Equilibrative nucleoside transporter 1
(1711 活性数据)
ADRA2B
Tclin
Alpha-2b adrenergic receptor
(4412 活性数据)
ADRA2C
Tclin
Alpha-2c adrenergic receptor
(4876 活性数据)
CHRM3
Tclin
Muscarinic acetylcholine receptor M3
(7750 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
ELANE
Tclin
Leukocyte elastase
(8173 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
ADORA2A
Tclin
Adenosine A2a receptor
(16305 活性数据)
关联靶点（其它种属）
TPR
Trypanothione reductase (189 活性数据)
ampC
Beta-lactamase AmpC (62480 活性数据)
Mc4r
Melanocortin receptor 4 (1205 活性数据)
Npy1r
Neuropeptide Y receptor type 1 (8 活性数据)
Cckar
Cholecystokinin A receptor (90 活性数据)
Pde4d
Phosphodiesterase 4D (4 活性数据)
Ggcx
Vitamin K-dependent gamma-carboxylase (85 活性数据)
Cdc25b
Dual specificity phosphatase Cdc25B (32 活性数据)
Mapk1
MAP kinase ERK2 (650 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
DLD
Dihydrolipoamide dehydrogenase (51 活性数据)
Pkm
Pyruvate kinase isozymes M1/M2 (66 活性数据)
Por
NADPH--cytochrome P450 reductase (42 活性数据)
Pseudomonas aeruginosa (123386 活性数据)
Staphylococcus aureus (210822 活性数据)
Escherichia coli (133304 活性数据)
Mycobacterium tuberculosis (203094 活性数据)
Trypanosoma brucei (78846 活性数据)
Trypanosoma brucei brucei (13300 活性数据)
Plasmodium falciparum (966862 活性数据)
Candida albicans (78123 活性数据)
Trichoplusia ni (986 活性数据)
Mus musculus (284745 活性数据)
Rattus norvegicus (775804 活性数据)
N2a (708 活性数据)
Vero (26788 活性数据)
HT-22 (3261 活性数据)
B16-F10 (4610 活性数据)
lef
Anthrax lethal factor (7585 活性数据)
Dusp6
Dual specificity protein phosphatase 6 (459 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
botA
Botulinum neurotoxin type A (1303 活性数据)
Dusp1
Dual specificity protein phosphatase 1 (15 活性数据)
BCHE
Cholinesterase (8742 活性数据)
Danio rerio (3092 活性数据)
Erwinia amylovora (182 活性数据)
Mycobacterium tuberculosis variant bovis BCG (1626 活性数据)
TGR
Thioredoxin glutathione reductase (28579 活性数据)
Mapt
Microtubule-associated protein tau (6 活性数据)
Rorc
Nuclear receptor ROR-gamma (89407 活性数据)
fba
Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
Impa1
Inositol monophosphatase 1 (16203 活性数据)
ffp
4'-phosphopantetheinyl transferase ffp (24982 活性数据)
GST
Glutathione S-transferase (6 活性数据)
CELA2A
Pancreatic elastase (395 活性数据)
Setaria cervi (263 活性数据)
gyrB
DNA gyrase subunit A/DNA gyrase subunit B (505 活性数据)
groL
GroEL/GroES (1042 活性数据)
groEL
60 kDa chaperonin (64 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
溶解性
油：可溶
熔点
105-108°C
分子量
172.180 g/mol
XLogP3
2.200
氢键供体数Hydrogen Bond Donor Count
0
氢键受体数Hydrogen Bond Acceptor Count
2
可旋转键计数Rotatable Bond Count
0
精确质量Exact Mass
172.052 Da
单同位素质量Monoisotopic Mass
172.052 Da
拓扑极表面积Topological Polar Surface Area
34.100 Ų
重原子数Heavy Atom Count
13
形式电荷Formal Charge
0
复杂度Complexity
288.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
0
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
信号词
警告
危险声明
H302: 吞食有害
H315: 引起皮肤刺激
H317: 可能引起皮肤过敏反应
H319: 引起严重眼睛刺激
H335: 可能引起呼吸道刺激
H341: 怀疑引起遗传缺陷
H361: 怀疑破坏生育力或未出生的孩子
H400: 对水生生物有剧毒
H410: 对水生生物有剧毒并具有长期持续影响
预防措施声明
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾
P264: 处理后要彻底洗手。
P270: 使用本产品时，请勿进食、饮水或吸烟。
P271: 仅在室外或通风良好的地方使用。
P272: 被污染的工作服不允许离开工作场所
P273: 避免释放到环境中。
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P281: 根据需要使用个人防护设备。
P321: 特殊处理（请参阅此标签上的...）。
P330: 漱口
P391: 收集溢出物
P302+P352: 如皮肤沾染：用水充分清洗。
P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。
P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。
P405: 密闭存放
P403+P233: 存放在通风良好的地方。保持容器密闭。
P501: 将内容物/容器处理到。。。
P203: 使用前，获取、阅读并遵守所有安全说明。
P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。
P301+P317: 如果被吞咽：请寻求医疗帮助。
P318: 如果暴露或担心，请就医。
P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany
3
RTECS
QL9100000
Merck Index
5831
个人防护装备
dust mask type N95 (US),Eyeshields,Faceshields,Gloves
质检证书（CoA,COO,BSE/TSE 和分析图谱)
技术文档和文章
Fluconazole: Physicochemical Properties, Mechanism of Action, and Key Points for Clinical and Research Applications
目录： 技术文章
Azithromycin: Physicochemical Features, Mechanism of Action, and Key Points for Research Applications
目录： 技术文章
Review of the Principles, Methods, and Application Considerations for Superoxide Dismutase Activity Determination
目录： 技术文章
Functional System Overview of Cellular Metabolic Enzymes in Energy Metabolism, Redox, and Signal Transduction
目录： 技术文章
氧化应激相关研究进展汇总
目录： 技术文章
How Coenzyme Q10 Acts on the Skin: Mitochondrial Electron Transfer, Antioxidant Protection of Membrane Lipids, and Lipid-Carrier Delivery
目录： 技术文章
Structural Characteristics of Ergothioneine, OCTN1-Mediated Uptake by Skin Cells, and Antioxidant Mechanisms
目录： 技术文章
Structural and Functional Differences Between Idebenone and Coenzyme Q10: From Side-Chain Structure to Redox Cycling and Mitochondrial Electron Transport
目录： 技术文章
此产品的引用文献
引用文献
| 1. Lei Jiang, Lin Yuan, Shan Gao, Yingying Xiang, Fei Song, Wensi Ma, Jing Wan, Xiuling Ji, Yujiao Tu. (2023) Facile hydrothermal synthesis of N-doped fluorescent carbon dots for selective detection of insecticide parathion. Analytical Methods, 15 (19): (2376-2381). [PMID:37132329] [10.1039/D3AY00124E] |
| 2. Huijun Wang, Jianxun Li, Chaoyang Zhang, Baoshan Sun, Yawen Zhou, Yanyan Zhou, Haiyu Zhao. (2023) Metabolomics approach, in vitro and in vivo antioxidant activity assay provide insights into impact of multiple variations on the vine tea (Ampelopsis grossedentata). LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2023.114578] |
| 3. Chen Xu, Rijin Song, Pei Lu, Jianchun Chen, Yongqiang Zhou, Gang Shen, Minjun Jiang, Wei Zhang. (2023) A pH-Responsive Charge-Reversal Drug Delivery System with Tumor-Specific Drug Release and ROS Generation for Cancer Therapy. International Journal of Nanomedicine, [PMID:32021165] [10.2147/IJN.S230237] |
| 4. Wang Hongkang, Ji Zhe, Feng Yanru, Yan Tianhua, Cao Yongbing, Lu Hui, Jiang Yuanying. (2022) Myriocin enhances the antifungal activity of fluconazole by blocking the membrane localization of the efflux pump Cdr1. Frontiers in Pharmacology, [PMID:36618949] [10.3389/fphar.2022.1101553] |
| 5. Yanjing Ou, Mingdong Yan, Guanglin Gao, Wenjie Wang, Qiaoqiao Lu, Jiang Chen. (2022) Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells. Food & Function, 13 (15): (8091-8106). [PMID:35792680] [10.1039/D2FO00963C] |
| 6. Jiahong Guo, Xiaoyu Ma, Fernando Bouffard, Sophia Yi Zhang. (2022) A Novel multi-fruit acids formula design on molecular basis for skin brightening via a system biology approach. Journal of Cosmetic Dermatology, 21 (11): (6145-6155). [PMID:35713107] [10.1111/jocd.15163] |
| 7. Fang Zhang, Fuwei Pan, Hairong Wang. (2022) Nisoldipine in Several Aqueous and Non-Aqueous Cosolvent Solutions: Solubility Modeling and Preferential Solvation Research. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [10.1021/acs.jced.1c00729] |
| 8. Kai Zhang, Zhonghui Zhuo, Guorong Fan, Zongde Wang, Shangxing Chen, Lulu Xu, Yangping Wen, Peng Wang. (2021) Nano-ZnS decorated hierarchically porous carbon electrocatalyst with multiple enzyme-like activities as a nanozyme sensing platform for simultaneous detection of dopamine, uric acid, guanine, and adenine. Nanoscale, 13 (47): (20078-20090). [PMID:34846060] [10.1039/D1NR06017A] |
| 9. Bingfeng Liang, Dangxia Zhou. (2021) ROS-Activated homodimeric podophyllotoxin nanomedicine with self-accelerating drug release for efficient cancer eradication. DRUG DELIVERY, [PMID:34747277] [10.1080/10717544.2021.1995076] |
| 10. Bailiang Wang, Liyang Zhou, Yishun Guo, Hanwen Guo, Yiming Zhong, Xiaomin Huang, Yifan Ge, Qingying Wang, Xiaoying Chu, Yingying Jin, Kaiyue Lan, Mei Yang, Jia Qu. (2021) Cyanobacteria-based self-oxygenated photodynamic therapy for anaerobic infection treatment and tissue repair. Bioactive Materials, [PMID:35128179] [10.1016/j.bioactmat.2021.10.032] |
| 11. Zhao Chenyu, Wang Guangshu, Sun Mengtao, Cai Zewei, Yin Zichu, Cai Yurong. (2021) Bacterial Cellulose Immobilized S. cerevisiae as Microbial Sensor for Rapid BOD Detection. FIBERS AND POLYMERS, 22 (5): (1208-1217). [10.1007/s12221-021-0650-5] |
| 12. Xiao Tu, Chenxi Duan, Siwei Wu, Shengli Fu, Jianmin Ye. (2021) Identification of plumbagin as an effective chemotherapeutic agent for treatment of Gyrodactylus infections. AQUACULTURE, [10.1016/j.aquaculture.2021.736372] |
| 13. Zhang Zhicheng, Ding Yawen, Li Jinbiao, Wang Li, Xin Xiaoyan, Yan Jing, Wu Jinhui, Yuan Ahu, Hu Yiqiao. (2020) Versatile iron-vitamin K3 derivative-based nanoscale coordination polymer augments tumor ferroptotic therapy. Nano Research, 14 (7): (2398-2409). [10.1007/s12274-020-3241-7] |
| 14. Xiuling Ji, Suping Wang, Yiyong Luo, Xiaotian Yuan, Yunlin Wei, Qi Zhang, Kunhao Qin, Yujiao Tu. (2020) Green synthesis of weissella-derived fluorescence carbon dots for microbial staining, cell imaging and dual sensing of vitamin B12 and hexavalent chromium. DYES AND PIGMENTS, [10.1016/j.dyepig.2020.108818] |
| 15. Yi Yu, Fanfan Li, Shanghai Long, Li Xu, Guoji Liu. (2020) Solubility, thermodynamic properties, HSP, and molecular interactions of vitamin K3 in pure solvents. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2020.113945] |
| 16. Wei Qi, Mengjie Li, Long Zhao. (2019) Effect of radiation on interfacial properties and phase behavior of ionic liquid-based microemulsions. RADIATION PHYSICS AND CHEMISTRY, [10.1016/j.radphyschem.2019.108596] |
| 17. Lin Yanke, Wang Shuai, Zhou Ziyue, Guo Lianxia, Yu Fangjun, Wu Baojian. (2019) Bmal1 regulates circadian expression of cytochrome P450 3a11 and drug metabolism in mice. Communications Biology, 2 (1): (1-11). [PMID:31633069] [10.1038/s42003-019-0607-z] |
| 18. Yi Yu, Xiaoqiang Gao, Zhouxuan Zang, Li Xu, Guoji Liu. (2019) Solid-liquid equilibrium for the ternary 2-naphthaldehyde + 2-methyl-1,4-naphthoquinone + ethanol system: Determination, correlation and molecular simulation. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2019.03.104] |
| 19. Jia Wang, Guangzhi Zeng, Xiaobing Huang, Zhe Wang, Ninghua Tan. (2017) 1,4-Naphthoquinone Triggers Nematode Lethality by Inducing Oxidative Stress and Activating Insulin/IGF Signaling Pathway in Caenorhabditis elegans. MOLECULES, 22 (5): (798). [PMID:28505088] [10.3390/molecules22050798] |
| 20. Fang Zhang, Long Wang, Yaocun Tang, Xiaoqiang Gao, Li Xu, Guoji Liu. (2015) Measurement and correlation of ternary solid–liquid equilibrium of 2-methyl-1,4-naphthoquinone + phthalic anhydride + acetone system. FLUID PHASE EQUILIBRIA, [10.1016/j.fluid.2015.09.019] |
| 21. Beiying Yang, Xiu Zeng, Yu Ge, Weining Liu, Wenxue Hao, Chunyingzi Long, Linkang Wang, Qianyue Wu, Yangping Wen, Jinhua Zhang. (2024) A new method for rapid, portable, low-cost detection of Clostridium perfringens β2 toxin in animal fecal using smartphone-based electrochemical immunosensor. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2024.110138] |
| 22. Jia-Yi Weng, Jia-Yu Yang, Ishimwe Steven Papy, Bu-Tao Yu, Yu-Feng Ke, Bing-Yu Bai, Mitchell N. Muskat, Qian Wu, Xiang-Rong Cheng. (2024) Cinnamaldehyde alleviates hepatic steatosis correlating with its electrophilic capability. Food Bioscience, [10.1016/j.fbio.2024.104142] |
| 23. Hai-Long Yu, Xiao-Long Liang, Zhen-Yang Ge, Zhi Zhang, Yao Ruan, Hao Tang, Qing-Ye Zhang. (2024) Metabolic Flux Analysis of Xanthomonas oryzae Treated with Bismerthiazol Revealed Glutathione Oxidoreductase in Glutathione Metabolism Serves as an Effective Target. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25 (22): (12236). [PMID:39596301] [10.3390/ijms252212236] |
| 24. Zhongcan Peng, Wenfeng Li, Yingchao Wang, Longping Zhu, Depo Yang, Guomin Zhao, Peng Zhong, Zhimin Zhao. (2025) The physicochemical properties of low molecular weight ‘Chachi’ (Citrus reticulata ‘Chachi’) pectins prepared by different modification methods and their modulation effects on the human gut microbiota. FOOD HYDROCOLLOIDS, [10.1016/j.foodhyd.2025.111350] |
| 25. Guoliang Ma, Zhiming Zheng, Han Wang, Li Wang, Genhai Zhao, Hengfang Tang, Xiumin Ding, Peng Wang. (2022) Preparation of Cellulose-Based Flocculant and Its Application in the Enrichment of Vitamin K2 in Fermentation Supernatant. Polymers, 14 (12): (2410). [PMID:35745984] [10.3390/polym14122410] |
| 26. Kangyuan Qu, Siyuan Xiong, Caiqian Huang, Xiaoxia Jiang, Lixia Tian, Shiwei Xie. (2024) Dietary supplementation of ornithine improved the growth, immune response and acute NH3 stress tolerance of Pacific white shrimp, Penaeus vannamei. Aquaculture Reports, [10.1016/j.aqrep.2024.102095] |
| 27. Li Wanqian, Whiteway Malcolm, Hang Sijin, Yu Jinhua, Lu Hui, Jiang Yuanying. (2025) Impairing the interaction between Erg11 and cytochrome P450 reductase Ncp1 enhances azoles’ antifungal activities. Nature Communications, 16 (1): (1-18). [PMID:40707518] [10.1038/s41467-025-62131-z] |
| 28. Xinyue Huang, Lei Jiang, Lin Yuan, Wensi Ma, Xintao Cui, Jiaxuan Liu, Xiuling Ji, YujiaoTu. (2025) Orange ratiometric fluorescent probe for sensitive detection of phoxim. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:40795714] [10.1016/j.saa.2025.126785] |
| 29. Renxiang Yuan, Shuqian Yang, Ding Wang, Caini Yu, Peirong Li, Qi Jiang, Yangqian Luo, Tingting Meng, Fuqiang Hu, Tong Yu, Yupeng Liu, Hong Yuan. (2025) Lipid-Modified Bilirubin Nanocrystals for the Repair of Ischemia-Reperfusion-Induced Acute Kidney Injury. MOLECULAR PHARMACEUTICS, [PMID:40832762] [10.1021/acs.molpharmaceut.5c00559] |
| 30. Tong Yu, Yeqing Wang, Yi Kong, Jianwei Wang, Hong Yun, Yunchao Wang, Fuqiang Hu, Zhongxin Zhu, Hong Yuan. (2025) Customized Design and Preparation of Bionic Drug Delivery System Leveraging Single-Cell RNA Sequencing for Precisely Targeted Therapy. Advanced Healthcare Materials, [PMID:40936355] [10.1002/adhm.202501497] |
| 31. Lei Lei, Wenbin Dai, Jinchao Zhao, Angfeng Jiang, Haisheng Peng, Qiao Jin, Xiaojing Li, Zhe Tang. (2025) A pH-Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition. Advanced Science, [PMID:40364727] [10.1002/advs.202504860] |
| 32. Wenjia Liu, Ying Wang, Xiangyu Hao, Yangxun Wang, Xiaofan Zhang, Jinchao Zhang, Kun Ge, Guoqiang Zhou. (2026) A novel pH-responsive nanoreactor for pyroptosis induction: multifaceted ROS amplification drives potent immunotherapy against triple-negative breast cancer. JOURNAL OF NANOBIOTECHNOLOGY, [PMID:42436485] [10.1186/s12951-026-04795-3] |
| 33. Junxi Liu, Yan Liu, Yuheng Zheng, Haoyu Wang, Jinglin Wang, Yu Zhang, Kaiping Wang. (2026) Intestinal metabolic characteristics of Smilax china L. pectic polysaccharide and prediction of its gut microbiota-mediated mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:42398606] [10.1016/j.ijbiomac.2026.153348] |
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