计算溶液所需的质量、体积或浓度。
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor ( EGFR ), with DC 50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a K i of 36 nM. PROTAC EGFR degrader 11 degrades EGFR , focal adhesion kinase ( FAK ), and RSK1 , inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC 50 <100 nM.