Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 1-5 ng/mL in the presence of 1 ng/mL of Recombinant Human IL-22.
Function Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy.
规格
产品名称
Recombinant Human IL-22BP Protein
别名
重组人IL-22BP蛋白 | 重组人白介素22受体α2蛋白
英文别名
class II cytokine receptor | CRF2-10 | CRF2-S1 | IL22BP | CRF2-X | Cytokine receptor class-II member 10 | Cytokine receptor family 2 member 10 | Cytokine receptor family type 2, soluble 1 | IL-22 RA2 | IL-22 receptor subunit alpha-2 | IL-22BP | CRF2X | IL
Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 1-5 ng/mL in the presence of 1 ng/mL of Recombinant Human IL-22.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
浓度
见COA
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IL-22BP Protein (rp147518) - SDS-PAGE 2 μg/lane of Recombinant Human IL-22BP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 40 - 58 kDa.
ZJ25F0521837
危险品化学品经营许可证（带存储）