基本描述

别名	(S)-(-)-2-吡咯烷酮-5-甲酸 \| (S)-5-氧-2-吡咯烷羧酸 \| L-2-吡咯烷酮-5-羧酸 \| 5-羧基吡咯烷酮 \| α-氨基戊二酸内酰胺
英文别名	L-5-Oxo-2-pyrrolidinecarboxylic acid \| L-Pyrrolidinonecarboxylate \| MLS001332421 \| DTXCID4026260 \| pyrrolidone car-boxylic acid \| (S)-5-Oxopyrrolidine-2-carboxylic Acid \| 2-Benzothiazolesulfenic acid morpholide \| (-)-Pyroglutamate \| (S)-(-)-2-Pyrrolidone-
规格或纯度	≥99%
英文名称	H-Pyr-OH
应用	A building block for pharmaceuticals and asymmetric synthesis
储存温度	充氩
运输条件	常规运输
产品介绍	L-Pyroglutamic acid is a building block for pharmaceuticals and asymmetric synthesis.A building block for pharmaceuticals and asymmetric synthesis L-Pyroglutamic acid is a building block for pharmaceuticals and asymmetric synthesis. A building block for pharmaceuticals and asymmetric synthesis

AI解读

关联靶点（人）

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 活性数据)

点击查看靶蛋白信息： PMP22

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Ralstonia solanacearum (520 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus thuringiensis (718 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Phytophthora infestans (820 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium berghei (192651 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 活性数据)

点击查看靶蛋白信息： rep

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudoperonospora cubensis (1623 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504751332
EC号	202-700-3
分子类型	小分子
IUPAC Name	(2S)-5-oxopyrrolidine-2-carboxylic acid
INCHI	InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
InChi Key	ODHCTXKNWHHXJC-VKHMYHEASA-N
Canonical SMILES	C1CC(=O)NC1C(=O)O
Isomeric SMILES	C1CC(=O)N[C@@H]1C(=O)O
WGK Germany	3
RTECS	TW3710000
PubChem CID	7405
分子量	129.11
Beilstein号	82132

化学和物理性质

溶解性	Soluble in water (10-15% at 20 °C), alcohol, acetone, DMSO, and methanol.
密度	1.38
敏感性	易吸潮
比旋光度	-10 ° (C=5, H2O)
熔点	152-162°C
分子量	129.110 g/mol
XLogP3	-0.800
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	129.043 Da
单同位素质量Monoisotopic Mass	129.043 Da
拓扑极表面积Topological Polar Surface Area	66.400 Å²
重原子数Heavy Atom Count	9
形式电荷Formal Charge	0
复杂度Complexity	154.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05, GHS07
信号词	Danger
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H318: 造成严重的眼睛损伤
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany	3
RTECS	TW3710000
Merck Index	8001
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

技术规格说明书

Purity(Neutralization titration)	98.5-101.5（%）
Melting point	157-164（℃）
Specific Rotation [a]20/D(c=5 in H2O)	-12--9（°）
Purity(HPLC)	99-100（%）
Appearance（P106004)	White to Off-White Powder or Crystals
Infrared spectrum	Conforms to Structure

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到9个结果

批号(Lot Number)	证书类型	日期	货号
F2115266	分析证书	25-03-04	P106004
D2120035	分析证书	25-02-07	P106004
C1921128	分析证书	23-01-11	P106004
B2308379	分析证书	22-06-27	P106004
B2308380	分析证书	22-06-27	P106004
I2212198	分析证书	22-06-27	P106004
I2212200	分析证书	22-06-27	P106004
I2212201	分析证书	22-06-27	P106004
G2215254	分析证书	21-05-31	P106004

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Zhao Zhenzhen, Liu Yanfeng, Liu Chao, Xu Qianqian, Song Meijie, Yan Hai. (2023) Whole-genome analysis of Comamonas sp. USTBZA1 for biodegrading diethyl phthalate. 3 Biotech, 13 (10): (1-11). [PMID:37670801] [10.1007/s13205-023-03736-3]
2. HongXun Sun, Shujia Song, Guo Zhao, Xiaochan Wang, Gang Liu. (2023) A Flexible and Wearable Chemiresistive Biosensor Fabricated by Laser Inducing for Real-Time Glucose Analysis of Sweat. Advanced Materials Interfaces, (2300281). [10.1002/admi.202300281]
3. Shuai Zhang, Mei Deng, Ruifen Zhang, Xuchao Jia, Fei Huang, Dong Zhao, Lihong Dong, Jianwei Chi, Zhida Sun, Qin Ma, Mingwei Zhang. (2023) Modulation effect of black rice dietary fiber on the metabolism and fermentation of cyanidin-3-glucoside in an in vitro human colonic model. Food & Function, 14 (14): (6707-6717). [PMID:37404037] [10.1039/D3FO00955F]
4. Dongbao Cai, Xusheng Li, Qingjie Xu, Haiwei Li, Ruijing Liu, Jiali Chen, Xinwei Jiang, Jianxia Sun, Caiyong Lai, Weibin Bai. (2023) Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage. Food & Function, 14 (4): (2200-2211). [PMID:36756975] [10.1039/D2FO03423A]
5. Zhipeng Huang, Yang Yang, Junju Mu, Genheng Li, Jianyu Han, Puning Ren, Jian Zhang, Nengchao Luo, Ke-Li Han, Feng Wang. (2023) Controlling the reactions of free radicals with metal-radical interaction. CHINESE JOURNAL OF CATALYSIS, 45 (120). [10.1016/S1872-2067(22)64181-0]
6. Hong Ding, Xiang Zhang, Zheng Liu, Juehan Wang, Ce Zhu, Qian Chen, Yong Huang, Youwei Ai, Ruibang Wu, Ganjun Feng, Li Zhang, Limin Liu. (2023) Construction of MOFs nanoplatform with pH-triggered release of protocatechuic acid for intervertebral disc degeneration therapy. MATERIALS & DESIGN, 225 (111493). [10.1016/j.matdes.2022.111493]
7. You-Rim Lee, Seungyeon Lee, Sohyen Kwon, Jiyeong Lee, Hee-Gyoo Kang. (2023) Effect of environmental conditions on bloodstain metabolite analysis. ENVIRONMENTAL RESEARCH, 216 (114743). [PMID:36356665] [10.1016/j.envres.2022.114743]
8. Haoyuan Li, Hongxiang Zhu, Zongyan Quan, Zhiping Chen, Lei Wang, Hui He. (2023) Tailoring of a bionic bifunctional cellulose nanocrystal-based gold nanocluster probe for the detection of intracellular pathological biomarkers. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 224 (1079). [PMID:36309238] [10.1016/j.ijbiomac.2022.10.192]
9. Shoufeng Tang, Huilin Liu, Eryu Zhu, Tongtong Zhao, Zetao Wang, Tifeng Jiao, Qingrui Zhang, Deling Yuan. (2022) Boosting peroxydisulfate Fenton-like reaction by protocatechuic acid chelated-Fe2+ with broad pH range. SEPARATION AND PURIFICATION TECHNOLOGY, 301 (122056). [10.1016/j.seppur.2022.122056]
10. Minjun Liu, Ying Liu, Xinru Liu, Chengcheng Chu, Ducheng Yao, Shun Mao. (2022) Peroxydisulfate activation by 2D MOF-derived Ni/Fe3O4 nanoparticles decorated in 3D graphene oxide network. SEPARATION AND PURIFICATION TECHNOLOGY, 301 (121967). [10.1016/j.seppur.2022.121967]
11. Xiuzhen Qiu, Yangyang Li, Yongbiao hua, Dongmei Liu, Kailian Zhou, Yulin Wang, Huishi Guo. (2022) A molecularly imprinted gel photonic crystal sensor for recognition of chiral amino acids. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 283 (121719). [PMID:35952590] [10.1016/j.saa.2022.121719]
12. Lu Geng, Zhou Jiawei, Yang Ting, Li Jin, Jiang Xinrui, Zhang Wenjun, Gu Shuangshuang, Wang Jun. (2022) Landscape of Metabolic Fingerprinting for Diagnosis and Risk Stratification of Sepsis. Frontiers in Immunology, 13 [PMID:35663956] [10.3389/fimmu.2022.883628]
13. Zhenzhu Zhu, Lipin Yang, Zhong Li, Qin Liu. (2022) Cyanidin-3-O-glucoside, cyanidin, and oxidation products of cyanidin protect neuronal function through alleviating inflammation and oxidative damage. JOURNAL OF FOOD SCIENCE, 87 (5): (2159-2172). [PMID:35340035] [10.1111/1750-3841.16125]
14. Xiaoli Song, Yang Lu, Yongling Lu, Lishuang Lv. (2021) Adduct Formation of Acrolein with Cyanidin-3-O-glucoside and Its Degradants/Metabolites during Thermal Processing or In Vivo after Consumption of Red Bayberry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 69 (44): (13143–13154). [PMID:34714663] [10.1021/acs.jafc.1c05727]
15. Zhiyu Xi, Canxin Xu, Xiao Chen, Baofeng Wang, Zhihong Zhong, Qingfang Sun, Yuhao Sun, Liuguan Bian. (2021) Protocatechuic Acid Suppresses Microglia Activation and Facilitates M1 to M2 Phenotype Switching in Intracerebral Hemorrhage Mice. Journal of Stroke & Cerebrovascular Diseases, 30 (105765). [PMID:33813082] [10.1016/j.jstrokecerebrovasdis.2021.105765]
16. Xinrong Jiang, Xiaoming Chen, Tao Wang, Yuexin Li, Aiwu Pan, Jianmin Wu. (2021) Perfluorinated polymer modified vertical silicon nanowires as ultra low noise laser desorption ionization substrate for salivary metabolites profiling. TALANTA, 225 (122022). [PMID:33592752] [10.1016/j.talanta.2020.122022]
17. Xiong Feng, Qin Zainen, Chen Haimin, Lan Qiumei, Wang Zetao, Lan Nihan, Yang Yuan, Zheng Li, Zhao Jinmin, Kai Dan. (2020) pH-responsive and hyaluronic acid-functionalized metal–organic frameworks for therapy of osteoarthritis. JOURNAL OF NANOBIOTECHNOLOGY, 18 (1): (1-14). [PMID:32993662] [10.1186/s12951-020-00694-3]
18. Hai-Ming Zhao, Rui-Wen Hu, Xue-Xue Chen, Xue-Bin Chen, Huixiong Lü, Yan-Wen Li, Hui Li, Ce-Hui Mo, Quan-Ying Cai, Ming-Hung Wong. (2018) Biodegradation pathway of di-(2-ethylhexyl) phthalate by a novel Rhodococcus pyridinivorans XB and its bioaugmentation for remediation of DEHP contaminated soil. SCIENCE OF THE TOTAL ENVIRONMENT, 640-641 (1121). [PMID:30021277] [10.1016/j.scitotenv.2018.05.334]
19. Ziyi Zhao, Guijin Liu, Qing Lin, Yanbin Jiang. (2018) Co-Crystal of Paracetamol and Trimethylglycine Prepared by a Supercritical CO2 Anti-Solvent Process. CHEMICAL ENGINEERING & TECHNOLOGY, 41 (6): (1122-1131). [10.1002/ceat.201700638]
20. Haibo Li, Zujin Yang, Jingnan Zhang, Yongchao Huang, Hongbing Ji, Yexiang Tong. (2017) Indium doped BiOI nanosheets: Preparation, characterization and photocatalytic degradation activity. APPLIED SURFACE SCIENCE, 423 (1188). [10.1016/j.apsusc.2017.06.301]
21. Xiujuan Xi, Shiqi Hu, Zhuxian Zhou, Xiangrui Liu, Jianbin Tang, Youqing Shen. (2016) Dendrimers with the protocatechuic acid building block for anticancer drug delivery. Journal of Materials Chemistry B, 4 (31): (5236-5245). [PMID:32263604] [10.1039/C6TB01597B]
22. Yanmei Yuan, Hong Tao, Jinhong Fan, Luming Ma. (2015) Degradation of p-chloroaniline by persulfate activated with ferrous sulfide ore particles. CHEMICAL ENGINEERING JOURNAL, 268 (38). [10.1016/j.cej.2014.12.092]

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溶液计算器

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计算溶液所需的质量、体积或浓度。

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稀释计算器

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
P106004-25g	25g	现货
P106004-100g	100g	现货
P106004-500g	500g	现货
P106004-2.5kg	2.5kg	现货

L-焦谷氨酸

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溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器