ATP-binding cassette sub-family G member 2 | Breast cancer resistance protein | CDw338 | EC 7.6.2.2 | Mitoxantrone resistance-associated protein | Placenta-specific ATP-binding cassette transporter | Urate exporter | ABC transporter antibody | ABC15 antib
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
宿主种属
兔(Rabbit)
特异性
ABCG2
种属反应性
人(Human)
预测反应种属
恒河猴(Rhesus Macaque)
免疫原
A synthetic peptide derived from human BCRP/ABCG2 (AA 150-200).
阳性对照
WB: HEK293, HeLa, Jurkat, Hep G2 and MCF7 cell lysates.
Recombinant BCRP/ABCG2 Antibody (Ab090883) - Western Blot All lanes: Recombinant BCRP/ABCG2 Antibody (Ab090883) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 72 kDa Observed band size: 75 kDa Exposure time: 30.0 s
ZJ24F0708379
危险品化学品经营许可证（带存储）