Mouse anti Human p53 Antibody, Recombinant (MyM1-p53), could be used for IHC and so on. Application IHC: 1/100-1/200 Protein Function Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
规格
产品名称
Recombinant p53 Antibody
别名
P53单克隆抗体|重组 p53 抗体
英文别名
Antigen NY-CO-13 antibody|BCC7 antibody|Cellular tumor antigen p53 antibody|FLJ92943 antibody|LFS1 antibody|Mutant tumor protein 53 antibody|p53 antibody|p53 tumor suppressor antibody|Phosphoprotein p53 antibody|Transformation related protein 53 antibody|Tp53 antibody|TRP53 antibody|tumor antigen p55 antibody|Tumor protein 53 antibody|Tumor protein p53 antibody|Tumor suppressor p53 antibody|Antigen NY-CO-13|BCC7|LFS1|LFS1TRP53|p53 tumor suppressor|p53|P53cellular tumor antigen p53|Phosphoprotein p53|TP53|transformation-related protein 53|TRP53|tumor protein p53|Tumor suppressor p53
Recombinant p53 Antibody (Ab119824) - IHC Immunohistochemistry analysis of paraffin-embedded human lung adenocarcinoma tissue labelling p53 with Recombinant p53 Antibody (Ab119824) at 1/200 dilution. The section was incubated with Ab119824 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
ZJ24F0505290
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