G2613076计算溶液所需的质量、体积或浓度。
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
有货
为什么选择此级别
PharmPure™,USP 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
2-8°C储存。低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 88 篇同行评审文献引用。
规格
英文别名
4bj8 | Acidum capobenicum [INN-Latin] | CHEBI:15956 | Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid, (3aS-(3aalpha,4beta,6aalpha))- | hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid | 2'-Keto-3,4-imidazolido-2-tetrahydrothiophene-N
规格或纯度
PharmPure™, USP
英文名称
Biotin
生化机理
对于氨基酸、能量代谢和脂肪酸合成有重要作用的必要维生素。它是四种哺乳类动物羧化酶中的辅基，促进二氧化碳的结合与输送。
储存条件
2-8°C储存
运输条件
低温运输
名称和识别符
PubChem SID
EC号
200-399-3
分子类型
小分子
IUPAC Name
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
INCHI
1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChi Key
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
Smiles
[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
Isomeric SMILES
C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
分子量
244.31
Beilstein号
86838
Reaxy-Rn
86838
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=86838&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 有机杂环化合物 |
| 类（Class) | 生物素及其衍生物 |
| 亚类（Subclass） | 暂无 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 生物素及其衍生物 |
| 其他上位类（Alternative Parents） | 咪唑羧酸及其衍生物 中链脂肪酸 硫杂脂肪酸 杂环脂肪酸 硫杂环戊烷 咪唑啉 异脲类 氮杂环化合物 甲脒类 羧酸 二烷基硫醚 一元羧酸及其衍生物 炔丙基型1,3-偶极有机化合物 碳氢化合物衍生物 有机光子化合物 有机氧化物 羰基化合物 |
| 分子骨架（Molecular Framework) | 脂肪族杂多环化合物 |
| 取代基（Substituents） | 2-碘苯酚 - 脂肪族杂多环化合物 - 氮杂环 - 生物素 - 羰基 - 羧酰亚胺 - 羧酰胺基 - 羧酸衍生物 - 二烷基硫醚 - 脂肪酸 - 脂肪酰基 - 杂环脂肪酸 - 烃衍生物 - 咪唑基羧酸衍生物 - 异脲 - 中链脂肪酸 - 单羧酸或其衍生物 - 有机1,3-双极性化合物 - 有机硝基化合物 - 有机氧化物 - 有机氧化合物 - 有机氮化合物 - 有机氧化合物 - 有机氮化合物 - 丙炔型1,3-双极性有机化合物 - 硫代脂肪酸 - 硫醚 - 硫杂环丁烷 |
| 描述（Description） | 该化合物属于生物素及其衍生物类有机化合物。这类化合物含有与四氢噻吩环共轭的脲基（四氢咪唑啉）环。 |
| 外部描述符（External Descriptors） | Water-soluble vitamins |
三维结构
交互式化学结构模型
关联靶点（人）
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
NR3C1
Tclin
Glucocorticoid receptor
(14987 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
ADRB2
Tclin
Beta-2 adrenergic receptor
(11824 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
ADRB1
Tclin
Beta-1 adrenergic receptor
(6630 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
VDR
Tclin
Vitamin D receptor
(26531 活性数据)
DRD2
Tclin
Dopamine D2 receptor
(23596 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
CNR1
Tclin
Cannabinoid CB1 receptor
(20913 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
HRH2
Tclin
Histamine H2 receptor
(5428 活性数据)
HTR2A
Tclin
Serotonin 2a (5-HT2a) receptor
(14758 活性数据)
HTR2C
Tclin
Serotonin 2c (5-HT2c) receptor
(11471 活性数据)
AVPR2
Tclin
Vasopressin V2 receptor
(2912 活性数据)
ADORA1
Tclin
Adenosine A1 receptor
(17603 活性数据)
AGTR1
Tclin
Type-1 angiotensin II receptor
(5176 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
PTGS2
Tclin
Cyclooxygenase-2
(13999 活性数据)
HRH1
Tclin
Histamine H1 receptor
(7573 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
AVPR1A
Tclin
Vasopressin V1a receptor
(5412 活性数据)
OPRD1
Tclin
Delta opioid receptor
(15096 活性数据)
OPRK1
Tclin
Kappa opioid receptor
(16155 活性数据)
HTR3A
Tclin
Serotonin 3a (5-HT3a) receptor
(3366 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
GRIN1
Tclin
Glutamate (NMDA) receptor subunit zeta 1
(122 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
CACNA1C
Tclin
Voltage-gated L-type calcium channel alpha-1C subunit
(766 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
SLC29A1
Tclin
Equilibrative nucleoside transporter 1
(1711 活性数据)
ADRA2B
Tclin
Alpha-2b adrenergic receptor
(4412 活性数据)
ADRA2C
Tclin
Alpha-2c adrenergic receptor
(4876 活性数据)
CHRM3
Tclin
Muscarinic acetylcholine receptor M3
(7750 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
ADORA2A
Tclin
Adenosine A2a receptor
(16305 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
BDKRB2
Tclin
Bradykinin B2 receptor
(3970 活性数据)
CHRNA4
Tclin
Neuronal acetylcholine receptor protein alpha-4 subunit
(1265 活性数据)
MC3R
Tchem
Melanocortin receptor 3
(5659 活性数据)
关联靶点（其它种属）
Mc4r
Melanocortin receptor 4 (1205 活性数据)
Npy1r
Neuropeptide Y receptor type 1 (8 活性数据)
Cckar
Cholecystokinin A receptor (90 活性数据)
Pde4d
Phosphodiesterase 4D (4 活性数据)
CHO-K1 (1115 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
Streptavidin (24 活性数据)
NS1
Nonstructural protein 1 (33327 活性数据)
Slco1a4
Solute carrier organic anion transporter family member 1A4 (114 活性数据)
Cenchrus americanus (77 活性数据)
Eif4a2
Eukaryotic initiation factor 4A-II (8 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
比旋光度
90.5 ° (C=2, 0.1mol/L NaOH)
熔点
232-233°C
分子量
244.310 g/mol
XLogP3
0.300
氢键供体数Hydrogen Bond Donor Count
3
氢键受体数Hydrogen Bond Acceptor Count
4
可旋转键计数Rotatable Bond Count
5
精确质量Exact Mass
244.088 Da
单同位素质量Monoisotopic Mass
244.088 Da
拓扑极表面积Topological Polar Surface Area
104.000 Ų
重原子数Heavy Atom Count
16
形式电荷Formal Charge
0
复杂度Complexity
298.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
3
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
WGK Germany
1
RTECS
XJ9088200
个人防护装备
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
质检证书（CoA,COO,BSE/TSE 和分析图谱)
技术文档和文章
抗体纯化的标签策略与应用
目录： 技术文章
链霉亲和素修饰蛋白的专业指南
目录： 技术文章
A Practical Guide to Small-Molecule Chemical Probes: Concept Clarification, Causal Validation, and Experimental Selection (with Product Navigation and Tables A–D)
目录： 技术文章
Protein Tags Demystified: Classification, Properties, and Suitable Experimental Applications
目录： 技术文章
Glycoprotein Hormone Family: Molecular Features, Signaling Bias, and In Vivo Pharmacokinetics
目录： 技术文章
Experimental Selection of NHS-LC-Biotin and Sulfo-NHS-LC-Biotin: Water Solubility, Membrane Permeability, and Differences in Application Scenarios
目录： 技术文章
Signal Transduction Mechanism of Graphene Biosensors: From Molecular Recognition to Electrical/Optical Signal Readout and Materials Selection
目录： 技术文章
此产品的引用文献
引用文献
| 1. Jun Yao. (2023) A multiple signal amplification photoelectrochemical biosensor based on biotin-avidin system for kanamycin sensing in fish and milk via synergism of g-C3N4 and Ru@SiO2. ANALYTICA CHIMICA ACTA, [PMID:38220276] [10.1016/j.aca.2023.342141] |
| 2. Yameng Zhao, Ruoning Fan, Chuyao Wang, Sen Xu, Long Xie, Jinghua Hou, Wen Lei, Jianjun Liu. (2023) Quantification and isotope abundance determination of 13C labeled intracellular sugar metabolites with hydrophilic interaction liquid chromatography. Analytical Methods, 15 (42): (5666-5673). [PMID:37855701] [10.1039/D3AY01178J] |
| 3. Yawen Zhang, Yue Wu, Yuping Yan, Yijing Ma, Linglan Tu, Jingjing Shao, Xuanyu Tang, Lingfeng Chen, Guang Liang, Lina Yin. (2023) Dual-Targeted Nanoparticle-In-Microparticle System for Ulcerative Colitis Therapy. Advanced Healthcare Materials, [PMID:37660262] [10.1002/adhm.202301518] |
| 4. Xinran Wang, Jieyi Pan, Haohui Shi, Na Liang, Shaoping Sun. (2023) Biotin-modified acid-sensitive micelles for enhancing antitumor effect of paclitaxel. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [10.1016/j.jddst.2023.104538] |
| 5. Qunhuan Ma, Li Zhang. (2023) The influences of dissolved inorganic and organic phosphorus on arsenate toxicity in marine diatom Skeletonema costatum and dinoflagellate Amphidinium carterae. JOURNAL OF HAZARDOUS MATERIALS, [PMID:37080037] [10.1016/j.jhazmat.2023.131432] |
| 6. Peiyun Cheng, Na Liang, Wei Zhao, Xianfeng Gong, Weijia Wang, Shaoping Sun. (2023) Chitosan-based near-infrared fluorescent micelles for controlled drug delivery and bioimaging in cancer therapy. EUROPEAN POLYMER JOURNAL, [10.1016/j.eurpolymj.2023.111974] |
| 7. Ying Gao, Jie Zhang, Jiexia Pan, Sanjun Ying, Bang Lou, Qingliang Yang, Weiyong Hong, Gensheng Yang. (2023) FOF1-ATP synthase molecular motor biosensor for miRNA detection of colon cancer. LIFE SCIENCES, [PMID:36841472] [10.1016/j.lfs.2023.121527] |
| 8. Bin Sun, Zhigang Wang, Bo Zhao, Yanfei Jin, Yaqiang Li, Song Yang. (2023) Preparation of biotin-labeled graphene film for detecting nerve growth factor. International Journal of Electrochemical Science, [10.1016/j.ijoes.2023.01.029] |
| 9. Huihui Yang, Xiaosen Bai, Baolong Feng, Qinghua Wang, Li Meng, Fengzhong Wang, Yutang Wang. (2022) Application of Molecular Transformer approach for predicting the potential reactions to generate advanced glycation end products in infant formula. FOOD CHEMISTRY, [PMID:36516683] [10.1016/j.foodchem.2022.135143] |
| 10. Qunhuan Ma, Lizhao Chen, Li Zhang. (2022) Effects of phosphate on the toxicity and bioaccumulation of arsenate in marine diatom Skeletonema costatum. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:36265640] [10.1016/j.scitotenv.2022.159566] |
| 11. Qi Han, Wenyi Dong, Hongjie Wang, Boping Yu, Peng Liu, Linshen Xie, Zhiguang Dai. (2022) Efficacy of the Toxicity Control during the Degradation of TBBPA by Ozonation. Water, 14 (16): (2543). [10.3390/w14162543] |
| 12. Weng Chunyue, Mi Zheyan, Li Meijing, Qin Haibin, Hu Zhongce, Liu Zhiqiang, Zheng Yuguo, Wang Yuanshan. (2022) Improvement of S-adenosyl-L-methionine production in Saccharomyces cerevisiae by atmospheric and room temperature plasma-ultraviolet compound mutagenesis and droplet microfluidic adaptive evolution. 3 Biotech, 12 (9): (1-15). [PMID:35975026] [10.1007/s13205-022-03297-x] |
| 13. Dan Gao, Sajid Asghar, Junxiu Ye, Mei Zhang, Rongfeng Hu, Yadong Wang, Lin Huang, Chengjun Yuan, Zhipeng Chen, Yanyu Xiao. (2022) Dual-targeted enzyme-sensitive hyaluronic acid nanogels loading paclitaxel for the therapy of breast cancer. CARBOHYDRATE POLYMERS, [PMID:35868795] [10.1016/j.carbpol.2022.119785] |
| 14. Lihua Chen, Pan Zhao, Jing Yang, Xiali Liao, Bo Yang, Chuanzhu Gao. (2022) Synthesis, characterization, and antitumor biological evaluation of novel fluorine-containing platinum (IV) complexes. APPLIED ORGANOMETALLIC CHEMISTRY, 36 (7): (e6759). [10.1002/aoc.6759] |
| 15. Yang Xu, Na Liang, Jiyang Liu, Xianfeng Gong, Pengfei Yan, Shaoping Sun. (2022) Design and fabrication of chitosan-based AIE active micelles for bioimaging and intelligent delivery of paclitaxel. CARBOHYDRATE POLYMERS, [PMID:35550783] [10.1016/j.carbpol.2022.119509] |
| 16. Xiang Yingying, Song Fei, Jiang Lei, Liu Ze, Tu Yujiao. (2022) Novel Fluorescent Nano Carbon Quantum Dots Derived From Lactarius Hatsudake for High Selective Vitamin B12 Detection. JOURNAL OF AOAC INTERNATIONAL, 105 (5): (1350-1359). [PMID:35244160] [10.1093/jaoacint/qsac033] |
| 17. Sida Ruan, Guiying Yang, Yuanzhen Dong, Wenwen Shangguan, Weigen Lu. (2021) Discovery of a Long-Acting Parathyroid Hormone 1–34 Analogue to Treat Hypoparathyroidism. MOLECULAR PHARMACEUTICS, [PMID:34482698] [10.1021/acs.molpharmaceut.1c00149] |
| 18. Jing Lv, Meiqiang Xie, Shufen Zhao, Wensheng Qiu, Shasha Wang, Manming Cao. (2021) Synergetic fabrication of hybrid drug formulation using biodegradable tri-block copolymeric liquid nanoparticle delivery for gastric cancer chemotherapy. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2021.117066] |
| 19. Zhao Wang, Bin Liu, Qianqian Sun, Lili Feng, Fei He, Piaoping Yang, Shili Gai, Zewei Quan, Jun Lin. (2021) Upconverted Metal–Organic Framework Janus Architecture for Near-Infrared and Ultrasound Co-Enhanced High Performance Tumor Therapy. ACS Nano, [PMID:34160201] [10.1021/acsnano.1c04280] |
| 20. Haohui Shi, Na Liang, Jiyang Liu, Siyi Li, Xianfeng Gong, Pengfei Yan, Shaoping Sun. (2021) AIE-active polymeric micelles based on modified chitosan for bioimaging-guided targeted delivery and controlled release of paclitaxel. CARBOHYDRATE POLYMERS, [PMID:34294339] [10.1016/j.carbpol.2021.118327] |
| 21. Xueqing Guo, Yang Liu, Wenjuan Dong, Qin Hu, Yong Li, Shaomin Shuang, Chuan Dong, Lishuai Cai, Xiaojuan Gong. (2021) Azithromycin detection in cells and tablets by N,S co-doped carbon quantum dots. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:33561684] [10.1016/j.saa.2021.119506] |
| 22. Xiuling Ji, Suping Wang, Yiyong Luo, Xiaotian Yuan, Yunlin Wei, Qi Zhang, Kunhao Qin, Yujiao Tu. (2020) Green synthesis of weissella-derived fluorescence carbon dots for microbial staining, cell imaging and dual sensing of vitamin B12 and hexavalent chromium. DYES AND PIGMENTS, [10.1016/j.dyepig.2020.108818] |
| 23. Hailong Tian, Jing Zhang, Huiyuan Zhang, Yue Jiang, Aixin Song, Yuxia Luan. (2019) Low side-effect and heat-shock protein-inhibited chemo-phototherapy nanoplatform via co-assembling strategy of biotin-tailored IR780 and quercetin. CHEMICAL ENGINEERING JOURNAL, [10.1016/j.cej.2019.123043] |
| 24. Zhang Yingyi, Li Liang, Wang Qi, Shen Mei, Han Weili, Yang Xuemei, Chen Lingyun, Ma Ande, Zhou Zhengzheng. (2019) Simultaneous determination of metabolic and elemental markers in methamphetamine-induced hepatic injury to rats using LC-MS/MS and ICP-MS. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 411 (15): (3361-3372). [PMID:31119349] [10.1007/s00216-019-01810-5] |
| 25. Menglu Xu, Sajid Asghar, Shuang Dai, Yajing Wang, Shanshan Feng, Liang Jin, Feng Shao, Yanyu Xiao. (2019) Mesenchymal stem cells-curcumin loaded chitosan nanoparticles hybrid vectors for tumor-tropic therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:31063785] [10.1016/j.ijbiomac.2019.04.201] |
| 26. Caixia Yan, Na Liang, Qiang Li, Pengfei Yan, Shaoping Sun. (2019) Biotin and arginine modified hydroxypropyl-β-cyclodextrin nanoparticles as novel drug delivery systems for paclitaxel. CARBOHYDRATE POLYMERS, [PMID:31047049] [10.1016/j.carbpol.2019.04.024] |
| 27. Wang Danfeng, Liang Na, Kawashima Yoshiaki, Cui Fude, Yan Pengfei, Sun Shaoping. (2019) Biotin-modified bovine serum albumin nanoparticles as a potential drug delivery system for paclitaxel. JOURNAL OF MATERIALS SCIENCE, 54 (11): (8613-8626). [10.1007/s10853-019-03486-9] |
| 28. Mengna Liu, Bingjie Wang, Chunjing Guo, Xiaoya Hou, Ziting Cheng, Daquan Chen. (2019) Novel multifunctional triple folic acid, biotin and CD44 targeting pH-sensitive nano-actiniaes for breast cancer combinational therapy. DRUG DELIVERY, [PMID:31571501] [10.1080/10717544.2019.1669734] |
| 29. Dai Xuanxuan, Yin Changtian, Zhang Yi, Guo Guilong, Zhao Chengguang, Wang Ouchen, Xiang Youqun, Zhang Xiaohua, Liang Guang. (2018) Osthole inhibits triple negative breast cancer cells by suppressing STAT3. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 37 (1): (1-11). [PMID:30577812] [10.1186/s13046-018-0992-z] |
| 30. Dan Cheng, Xuelian Xiao, Xi Li, Chen Wang, Yani Liang, Zhengsong Yu, Chenglong Jin, Nan Zhou, Ming Chen, Yulin Dong, Yawei Lin, Zhizhong Xie, Chaocan Zhang. (2018) A Non-Enzymatic Electrochemical Sensing Platform Based on Hemin@MOF Composites for Detecting Hydrogen Peroxide and DNA. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 165 (16): (B885). [10.1149/2.0841816jes] |
| 31. Lijun Hu, Min Li, Zhipeng Zhang, Yuanyuan Shen, Shengrong Guo. (2018) Self-assembly of biotinylated poly(ethylene glycol)-poly(curcumin) for paclitaxel delivery. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:30308274] [10.1016/j.ijpharm.2018.10.019] |
| 32. Zihao Li, Chenggang Zhu, Zhihe Guo, Bowen Wang, Xiang Wu, Yiyan Fei. (2018) Highly Sensitive Label-Free Detection of Small Molecules with an Optofluidic Microbubble Resonator. Micromachines, 9 (6): (274). [PMID:30424207] [10.3390/mi9060274] |
| 33. Wen Jingbai, Xiao Yanqiu, Liu Ting, Gao Qiuqiang, Bao Jie. (2018) Rich biotin content in lignocellulose biomass plays the key role in determining cellulosic glutamic acid accumulation by Corynebacterium glutamicum. Biotechnology for Biofuels, 11 (1): (1-12). [PMID:29760774] [10.1186/s13068-018-1132-x] |
| 34. Juan Chen, Zhongming Huang, Hongmin Meng, Lin Zhang, Danyang Ji, Juanzu Liu, Fei Yu, Lingbo Qu, Zhaohui Li. (2018) A facile fluorescence lateral flow biosensor for glutathione detection based on quantum dots-MnO2 nanocomposites. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2018.01.101] |
| 35. Zhipeng Zhang, Yun Wang, Shaohui Xu, Yanna Yu, Abid Hussain, Yuanyuan Shen, Shengrong Guo. (2017) Photothermal gold nanocages filled with temperature sensitive tetradecanol and encapsulated with glutathione responsive polycurcumin for controlled DOX delivery to maximize anti-MDR tumor effects. Journal of Materials Chemistry B, 5 (27): (5464-5472). [PMID:32264086] [10.1039/C7TB01253E] |
| 36. Qingrui Yang, Shuting Pan, Yuan Zhao, Hao Zhang, Wei Pang, Xuexin Duan. (2017) Biomolecular stiffness detection based on positive frequency shift of CMOS compatible gigahertz solidly mounted resonators. BIOSENSORS & BIOELECTRONICS, [PMID:28499197] [10.1016/j.bios.2017.05.002] |
| 37. Luyan Sun, Jiaxun Wan, Christian G. Schaefer, Zihao Zhang, Jing Tan, Jia Guo, Limin Wu, Changchun Wang. (2017) Specific On-site Assembly of Multifunctional Magnetic Nanocargos Based on Highly Efficient and Parallelized Bioconjugation: Toward Personalized Cancer Targeting Therapy. ACS Biomaterials Science & Engineering, [PMID:33465935] [10.1021/acsbiomaterials.6b00773] |
| 38. Chenggang Zhu, Xiangdong Zhu, James P. Landry, Zhaomeng Cui, Quanfu Li, Yongjun Dang, Lan Mi, Fengyun Zheng, Yiyan Fei. (2016) Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry. SENSORS, 16 (3): (378). [PMID:26999137] [10.3390/s16030378] |
| 39. Guo Shengrong, Lv Li, Shen Yuanyuan, Hu Zhongliang, He Qianjun, Chen Xiaoyuan. (2016) A nanoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrug resistant breast cancer. Scientific Reports, 6 (1): (1-11). [PMID:26875787] [10.1038/srep21459] |
| 40. Shengguo Lu, Fang Luo, Xujia Duan, Chen Jia, Yuwang Han, He Huang. (2014) Hybrid polydiacetylene/magnetite nanoparticles: Sensing for sodium cetyltrimethylammonium bromide and streptavidin. JOURNAL OF APPLIED POLYMER SCIENCE, 131 (16): [10.1002/app.40634] |
| 41. Jianyong Li, Xiaojun Kong, Xiwang Li, Yajun Yang, Jiyu Zhang. (2013) Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay. FOOD AND CHEMICAL TOXICOLOGY, [PMID:24140966] [10.1016/j.fct.2013.10.010] |
| 42. Yanrong Zhang, Qin Tu, Dong-En Wang, Yun Chen, Bingzhang Lu, Mao-Sen Yuan, Jinyi Wang. (2013) Adamantyl-terminated dendronized molecules: synthesis and interaction with β-cyclodextrin-functionalized poly(dimethylsiloxane) interface. NEW JOURNAL OF CHEMISTRY, 37 (8): (2358-2368). [10.1039/C3NJ00129F] |
| 43. Donghua Liu, Fengxi Liu, Zhihong Liu, Lili Wang, Na Zhang. (2011) Tumor Specific Delivery and Therapy by Double-Targeted Nanostructured Lipid Carriers with Anti-VEGFR-2 Antibody. MOLECULAR PHARMACEUTICS, [PMID:21923159] [10.1021/mp200402e] |
| 44. Yongjun Liu, Zhijin Chen, Chunxi Liu, Dexin Yu, Zaijun Lu, Na Zhang. (2011) Gadolinium-loaded polymeric nanoparticles modified with Anti-VEGF as multifunctional MRI contrast agents for the diagnosis of liver cancer. BIOMATERIALS, [PMID:21521627] [10.1016/j.biomaterials.2011.03.077] |
| 45. Luo Juan, Yu Yao, Wang Ke, He Sizhe, Wang Longjie, Liang Fangfang, Chin Jason W., Tang Shan. (2024) Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification. Nature Protocols, [PMID:38867073] [10.1038/s41596-024-01006-x] |
| 46. Mengjing Xu, Mengjing Xu, Boyang Shi, Haofeng Li, Xiaohan Mai, Lan Mi, Jiong Ma, Xiangdong Zhu, Guowei Wang, Guowei Wang, Yiyan Fei, Yiyan Fei, Yiyan Fei. (2024) Development of a carboxymethyl chitosan functionalized slide for small molecule detection using oblique-incidence reflectivity difference technology. Biomedical Optics Express, 15 (10): (5947-5959). [PMID:39421793] [10.1364/BOE.534563] |
| 47. Xinyue Lu, Qiyan Zhang, Zejia Wang, Xuanzhi Cheng, Huiru Yan, Shuyi Cai, Huawei Zhang, Qikun Liu. (2024) Development of an inducible DNA barcoding system to understand lineage changes in Arabidopsis regeneration. DEVELOPMENTAL CELL, [PMID:39591964] [10.1016/j.devcel.2024.10.023] |
| 48. Chenyue Kang, Caihong Zhang, Yan Zhang, Guomei Zhang, Shaomin Shuang. (2024) Dual-emission ratio fluorescent probe based on carbon dots and copper-silver bimetallic nanoclusters for visual and fluorescent detection of ciprofloxacin. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2024.110810] |
| 49. Na Liang, Caixia Yan, Zhenrong Liu, Wenlong Hu, Kun Jiang, Gang Li, Shaoping Sun. (2024) Functionalized hydroxypropyl-β-cyclodextrin derivative as a versatile nanovehicle for delivery of paclitaxel. JOURNAL OF POLYMER SCIENCE, [10.1002/pol.20230833] |
| 50. Jia Fu, Wei Zhao, Na Liang, Shaoping Sun. (2025) Functionalized hydroxypropyl-β-cyclodextrin inclusion complex for combined tumor therapy through intelligent delivery of paclitaxel and polarization of M2-like tumor associated macrophages. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:40158248] [10.1016/j.colsurfb.2025.114654] |
| 51. Ke Ma, Meng Yin, Xiao-Xue Wang, Chen-Yu Wang, Ke-Zheng Chen, Sheng-Lin Qiao. (2024) Gold Nanocluster-Based Nanozyme for High-Throughput Colorimetric Detection of SARS-CoV-2. ACS Applied Nano Materials, [10.1021/acsanm.4c01049] |
| 52. Tingbiao Wu, Deyao Li, Qiuyu Chen, Dezhi Kong, Hongxuan Zhu, Hefeng Zhou, Qingwen Zhang, Guozhen Cui. (2024) Identification of VDAC1 as a cardioprotective target of Ginkgolide B. CHEMICO-BIOLOGICAL INTERACTIONS, [PMID:39716534] [10.1016/j.cbi.2024.111358] |
| 53. Yang Ya-qi, Liu Yi-jun, Qiao Wen-xuan, Jin Wei, Zhu Shun-wei, Yan Yu-xi, Luo Qiong, Xu Qiang. (2024) Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren’s syndrome in mice by promoting TEC kinase degradation. ACTA PHARMACOLOGICA SINICA, [PMID:38744938] [10.1038/s41401-024-01288-7] |
| 54. Baoyan Ding, Wei Meng, Xiaoling Zang, Zhihua Lv. (2024) Metabolic characteristics of prostate cancer cells with high metastatic potential revealed by (S)-ethyl 1-(3-(4-chlorophenoxy)-2-hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate inhibition. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:39662125] [10.1016/j.jpba.2024.116611] |
| 55. Siyi Li, Kexin Li, Xianfeng Gong, Pengfei Yan, Shaoping Sun. (2024) pH-Induced color changeable AIE-featured polymeric micelles for self-indicating anticancer drug delivery. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2024.136637] |
| 56. Jialuo Ai, Yixuan Huang, Zhaoyi Yin, Yingshan Deng, Ling Yan, Jingwen Liao, Guoyan Liang, Chong Chen, Yunbing Chang, Cairong Xiao, Jiale Zhou, Zurong Zhu, Chengli Liu, Zhuo Jiang, Chengyun Ning, Zhengao Wang. (2024) SEA Anemone-inspired Conducting Polymer Sensing Platform for Integrated Detection of Tumor Protein Marker and Circulating Tumor Cell. Advanced Healthcare Materials, [PMID:38767216] [10.1002/adhm.202401305] |
| 57. Guosheng Zhang, Anqi Han, Nuo Li, Mingya Yang, Guoqing Yan, Zhigang Cao, Jinhui Shi, Sheng Zhou, Lei Shan, Benli Yu. (2024) Specific, sensitive, and reliable sensing of cancer cells based on quantum dot/hydrogel-coated double optical fiber ball. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2024.136100] |
| 58. Menglan Wang, Lewei Li, Lifang Tang, Zuowei Xiao, Hong Yang, Qian Luo, Shiyang Fu, Zehui Fan, Xiaojun Tao, Chunlian He, Xiong Wu. (2025) Synergistic anti-Triple Negative Breast Cancer Study with Paclitaxel/Berberine Nanoparticle Co-Delivery System. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [10.1016/j.jddst.2025.106835] |
| 59. Yunkai Sun, Xiaoxia Wu, Pei Zuo, Zhao Liu, Xuepei Miao, Jian Liu, Hairuo Wen. (2024) Synthesis and mutagenic risk of avanafil's potential genotoxic impurities. RSC Advances, 14 (30): (21432-21438). [PMID:38979469] [10.1039/D4RA02345E] |
| 60. Li Wenguo, Peng Junjiang, Yao Deqiang, Rao Bing, Xia Ying, Wang Qian, Li Shaobai, Cao Mi, Shen Yafeng, Ma Peixiang, Liao Rijing, Qin An, Zhao Jie, Cao Yu. (2024) The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex. Nature Communications, 15 (1): (1-14). [PMID:39245686] [10.1038/s41467-024-52321-6] |
| 61. Peng Junjiang, Li Wenguo, Yao Deqiang, Xia Ying, Wang Qian, Cai Yan, Li Shaobai, Cao Mi, Shen Yafeng, Ma Peixiang, Liao Rijing, Zhao Jie, Qin An, Cao Yu. (2025) The structural basis for the human procollagen lysine hydroxylation and dual-glycosylation. Nature Communications, 16 (1): (1-13). [PMID:40069201] [10.1038/s41467-025-57768-9] |
| 62. Na Liang, Wei Zhao, Siyi Li, Xiaoxin Li, Zhenrong Liu, Kun Jiang, Shaoping Sun. (2024) Tumor targeting pH-triggered fluorescence-switchable hyaluronic acid-based micelles with aggregation-induced emission activity for tracing drug release and intelligent drug delivery. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39111498] [10.1016/j.ijbiomac.2024.134386] |
| 63. Qiang Zhang, Junlei Zhao, Anqi Han, Xiaonan Zhang, Mingya Yang, Hui Li, Benli Yu, Guosheng Zhang, Sheng Zhou. (2024) Ultrasensitive cancer cell sensing based on tapered optical fiber operating near the dispersion turning point. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2024.135473] |
| 64. Wenjuan Dong, Lu Wang, Rongrong Zhang, Chaochao Wen, Ren Su, Xiaojuan Gong, Wenting Liang. (2023) High luminescent N,S,P co-doped carbon dots for the fluorescence sensing of extreme acidity and folic acid. DALTON TRANSACTIONS, 52 (19): (6551-6558). [PMID:37185994] [10.1039/D3DT00560G] |
| 65. Xiao-lei Wang, Qi Wang, Ya-xian Xue, Bing Zhang, Shu-rui Han, Huan Zhang, Kong-yin Zhao, Wan Wang, Jun-fu Wei. (2023) Preparation of composite nanofiltration membrane with interlayer for pharmaceutical rejection. SEPARATION AND PURIFICATION TECHNOLOGY, [10.1016/j.seppur.2023.123411] |
| 66. Chuanjiang Jian, Ying Wang, Huijun Liu, Zongning Yin. (2022) A biotin-modified and H2O2-activatable theranostic nanoplatform for enhanced photothermal and chemical combination cancer therapy. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, [PMID:35667614] [10.1016/j.ejpb.2022.05.019] |
| 67. Jie Zhang, Boyou Zhang, Zefeng Zheng, Qingyun Cai, Jingcheng Wang, Qiang Shu, Lijia Wang. (2021) Tissue-Engineered Bone Functionalized with MoS2 Nanosheets for Enhanced Repair of Critical-Size Bone Defect in Rats. ADVANCED FUNCTIONAL MATERIALS, 32 (13): (2109882). [10.1002/adfm.202109882] |
| 68. Mengying Luo, Wenwen Wang, Qinghua Zhao, Mufang Li, Yuanli Chen, Zhentan Lu, Ke Liu, Dong Wang. (2017) Chemiluminescence biosensor for hydrogen peroxide determination by immobilizing horseradish peroxidase onto PVA-co-PE nanofiber membrane. EUROPEAN POLYMER JOURNAL, [10.1016/j.eurpolymj.2017.04.018] |
| 69. Kangyuan Qu, Siyuan Xiong, Caiqian Huang, Xiaoxia Jiang, Lixia Tian, Shiwei Xie. (2024) Dietary supplementation of ornithine improved the growth, immune response and acute NH3 stress tolerance of Pacific white shrimp, Penaeus vannamei. Aquaculture Reports, [10.1016/j.aqrep.2024.102095] |
| 70. Zhenrong Liu, Zhe Zong, Xiaoxin Li, Shaoping Sun. (2025) Smart Polymeric Micelles with Aggregation-Induced Emission and pH-Responsive Fluorescence Color Change Behavior for Bioimaging and Cancer Therapy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26 (14): (6654). [PMID:40724905] [10.3390/ijms26146654] |
| 71. Qiang Wan, Rong Li, Meiping Ren, Gang Ke. (2025) Hydrothermally Synthesized Boletus Brucella-derived Carbon Quantum Dots as a Fluorescent Probe for the Detection of Vitamin B2. Current Nanoscience, 21 (1): (92-98). [10.2174/0115734137259719230921065320] |
| 72. Qian Wang, Kexin Liu, Kunming Xing, Yuyan Li, Yumin Liu, Guangyao Tan, Yingnan Sun, Shusheng Zhang. (2025) Dual-mode droplet rolling strategy: Mimicking Earth's rotation and revolution for dual-cycle synergy in the efficient capture and controlled release of trace targets. LAB ON A CHIP, [PMID:40370282] [10.1039/D5LC00110B] |
| 73. Xiaoshuang Dai, Daobin Jiang, Chunlin Gou, Ke Mei, Bin Sun, Jianpeng Liu, Na Yao, Xinyu Liu, Neng Qiu. (2025) Biotinylated Self-Assembled Cytarabine Nano-Prodrug with Enhanced Targetability and Anticancer Efficacy: An In Vitro Study. LANGMUIR, [PMID:40450601] [10.1021/acs.langmuir.5c01147] |
| 74. Zhe Zong, Wei Zhao, Siyi Li, Na Liang, Shaoping Sun. (2025) Hydroxypropyl-β-Cyclodextrin-Based Micelles With Aggregation-Induced Emission Activity and Redox-Responsiveness for Smart Cancer Therapy. JOURNAL OF APPLIED POLYMER SCIENCE, [10.1002/app.57394] |
| 75. Yifan Li, Zhen Chen, Wei Hong, Tao Feng, Xiwei Tian, Ju Chu. (2025) Application of Transcriptome Analysis for the Exploration of the Mechanism of Methionine Promoting the Synthesis of Cephalosporin C in Acremonium chrysogenum by Employing a Chemically Defined Medium. Fermentation-Basel, 11 (6): (325). [10.3390/fermentation11060325] |
| 76. Yuan-Yuan Yang, Bao-Zhu Jia, Zhen-Lin Xu, Yi-Xian Liu, Lin Luo. (2025) Magnetic Particle-Based Automated Chemiluminescence Immunoassay for the Determination of Hydrocortisone Residues in Milk. Foods, 14 (12): (2105). [PMID:40565714] [10.3390/foods14122105] |
| 77. Siyue Wang, Xiaotian Guan, Shuqing Sun. (2025) CRISPR/Cas12a-Based Aptasensor Enhanced by Functionalized AuNPs for Sensitive Full-Range C-Reactive Protein Detection. Journal of Materials Chemistry B, [PMID:41170688] [10.1039/D5TB01727K] |
| 78. Zhi-Hua Deng, Liang-Jun He, Shanshan Wei, Chang-Sheng Li, Ya Chen, Xin-Yi Ai, Chatchai Chaotham, Supat Jiranusornkul, Pei-Cheng Zhang, Zhuo Luo, Shang-Ping Xing, Jie Yang. (2025) Unveiling plumbagin as a novel metabolic modulator to suppress ACC1-mediated de novo lipogenesis in non-small cell lung cancer. PHYTOMEDICINE, [PMID:41187651] [10.1016/j.phymed.2025.157438] |
| 79. Weiwei Ma, Yan Zhang, Xuejing Zhai, Qian Qu, Xueying Guo, Sen Zhang, Ruiyao Hou, Ping Lu, Yanyan Yin. (2025) Polysarcosine-Functionalized Graphene Oxide Improves Biological Safety and Enhances Chemo-Photothermal Therapy Synergistic Anticancer Effect. International Journal of Nanomedicine, [PMID:41451167] [10.2147/IJN.S552175] |
| 80. Li Yixian, Yang Xiaohui, Cheng Shanshan, Mu Rongrong, Li Huiqiang, Yu Yang. (2025) A bidirectional immuno-microfluidic chip for detecting autoantibodies based on an indirect assay. MICROCHIMICA ACTA, 193 (1): (28). [PMID:41405727] [10.1007/s00604-025-07743-4] |
| 81. Jiahui Cai, Yuwei Du, Huimin Miao, Yingge Cong, Minghui Zan, Ruhong Yan, Li Li, Juan Yue. (2026) Multifunctional sulfur-doped carbon dots for tetracycline residue analysis in food and intracellular lysosomal pH tracking. DYES AND PIGMENTS, [10.1016/j.dyepig.2025.113547] |
| 82. Yan Wang, Yitian Yu, Nuohan Xu, Zhenyan Zhang, Bingfeng Chen, Minglong Song, Qi Zhang, Tingzhang Wang, Yunting Ma, Tao Lu, Liwei Sun, Haifeng Qian. (2026) Genes for Vitamin B Synthesis and Their Distribution in Microbial Producers. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:41503787] [10.1021/acs.jafc.5c11883] |
| 83. Qiang-Ming Li, Man-Lei Zhu, Xiang Li, Jing-Xing He, Xue-Qiang Zha, Jian-Ping Luo, Feng-Yun Zhang. (2026) DDX17 acts as a target of Buddlejasaponin IVb ameliorating dopaminergic neuron iron metabolism dysregulation in Parkinson’s disease. PHYTOMEDICINE, [PMID:41691986] [10.1016/j.phymed.2026.157938] |
| 84. Na Yao, Lian Deng, Ziqing Weng, Yang Song, Ning Lei, Junda Liu, Neng Qiu. (2026) Inclusion complex of biotinylated podophyllotoxin with hydroxypropyl-β-cyclodextrin: enhanced solubility, tumor selectivity and efficacy. JOURNAL OF MOLECULAR STRUCTURE, [10.1016/j.molstruc.2026.145666] |
| 85. Dianjiang Yu, Haofeng Chen, Yang Zhang, Yueyang Chen, Hongwei Chen, Shujin Lin, Junyi Wang, Haoyi Yang, Xueping Ling, Ning He, Jifeng Yuan. (2026) Biosensor-guided indexing of genome evolution for boosting microbial chemical synthesis. TRENDS IN BIOTECHNOLOGY, [PMID:41741258] [10.1016/j.tibtech.2025.12.019] |
| 86. Yumei Hu, Yuhang Xu, Biyu He, Du Niu, Xuechun Yang, Jiaping Huang, Zhenzhen Xie, Panpan Shen, Xian Li, Maosen Bai, Ziwei Liu, Hao Li, Yunyun Yang, Jian-Wen Huang, Chun-Chi Chen, Rey-Ting Guo, Longhai Dai. (2026) Structure-guided protein engineering and immobilization of an amidohydrolase for efficient ochratoxin A detoxification. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [10.1016/j.ijbiomac.2026.151671] |
| 87. Zhengqi Wang, Yangliu Zhou, Bo Qian, Mingya Yang, Xiaonan Zhang, Benli Yu, Sheng Zhou. (2026) Ultra-Sensitive Cancer Cell Detection Based on the Vernier Effect of Taper-In-Taper Structured Optical Fibers. MICROWAVE AND OPTICAL TECHNOLOGY LETTERS, 68 (7): (e70699). [10.1002/mop.70699] |
| 88. Xiaoshuang Dai, Na Yao, Xinyu Liu, Ke Mei, Bin Sun, Ziqing Weng, Jianpeng Liu, Junda Liu, Ning Lei, Neng Qiu. (2026) Design and synthesis of self-assembled ferulic acid-biotin nanoprodrugs with GSH/pH-responsive behavior and in vitro anticancer activity. JOURNAL OF MOLECULAR STRUCTURE, [10.1016/j.molstruc.2026.146973] |
溶液计算器
常见问题
本产品的 CAS 号、分子式和分子量是多少？
本产品的 CAS 号为 58-85-5，分子式为 C10H16N2O3S，分子量为 244.31 g/mol。InChIKey YBJHBAHKTGYVGT-ZKWXMUAHSA-N。
本产品如何运输？
本产品采用湿冰冷藏运输。收货后请立即拆包，并按上述储存条件保存。
什么是「PharmPure?」？
「PharmPure?」指按照药品生产和受监管的工作流程要求生产和管控的物料。根据具体类别（GMP、RUO、生物医学级、注射级等），这可能包括受控的生产环境、经验证的工艺、可供审计的文件以及可追溯性。
什么是「USP」？
「USP」表示该物料符合相应药典（USP）的已发布专论。规格包括鉴别、含量测定、杂质限值、残留溶剂以及专论中定义的其他检测。符合「USP」的物料适用于符合药典的药用，包括药品生产、QC 和法规申报。
本产品应如何储存？
请于2–8 °C条件下保存。需冷藏保存以维持规定的有效期。
如何获取批次专用COA？
每个订单都会随附分析证书（COA），您也可以从账户订单历史中下载。如需订购前的COA，请联系您的客户代表，或使用PDP上的"申请COA"按钮——我们将提供代表性批次的COA。
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
Copyright © 2023至今 上海阿拉丁生化科技股份有限公司 保留所有权利。
危险品化学品经营许可证（带存储）