Rabbit anti Human MADH7/SMAD7 Antibody, Polyclonal, could be used for WB and so on. Application WB: 1/500-1/2000 Protein Function Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
规格
产品名称
MADH7/SMAD7 Antibody
别名
Smad7抗体|MADH7/SMAD7 抗体
英文别名
CRCS3|hSMAD7|MAD homolog 7|MAD homolog 8|MAD, mothers against decapentaplegic homolog 7 (Drosophila)|MADH7|MADH7mothers against decapentaplegic homolog 7|MADH8|Mothers against decapentaplegic homolog 8|Mothers against decapentaplegic, drosophila, homolog of, 7|Mothers against DPP homolog 7|Mothers against DPP homolog 8|SMAD 7|SMAD family member 7MAD (mothers against decapentaplegic, Drosophila) homolog 7|SMAD, mothers against DPP homolog 7 (Drosophila)|SMAD, mothers against DPP homolog 7|Smad7|CRCS3 antibody|FLJ16482 antibody|hSMAD 7 antibody|hSMAD7 antibody|MAD (mothers against decapentaplegic Drosophila) homolog 7 antibody|MAD antibody|Mad homolog 7 antibody|MAD homolog 8 antibody|MAD mothers against decapentaplegic homolog 7 antibody|MADH 7 antibody|MADH 8 antibody|MADH6 antibody|MADH7 antibody|MADH8 antibody|Mothers Against Decapentaplegic Drosophila Homolog of 6 antibody|Mothers Against Decapentaplegic Drosophila Homolog of 7 antibody|Mothers against decapentaplegic homolog 7 antibody|Mothers against decapentaplegic homolog 8 antibody|Mothers against DPP homolog 7 antibody|Mothers against DPP homolog 8 antibody|SMA- AND MAD-RELATED PROTEIN 7 antibody|SMAD 7 antibody|SMAD antibody|SMAD family member 7 antibody|SMAD, mothers against DPP homolog 7 (Drosophila) antibody|SMAD, mothers against DPP homolog 7 antibody|SMAD6 antibody|Smad7 antibody
MADH7/SMAD7 Antibody (Ab113970) - Western Blot All lanes: MADH7/SMAD7 Antibody (Ab113970) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 42 kDa Exposure time: 21.3 s
应用
应用名称
稀释比例
WB
1/500-1/2000
高级数据
关联靶点（人）
SMAD7Tbio母亲反对 decapentaplegic 同源物 7(Mothers against decapentaplegic homolog 7)
(0 活性数据)
ZJ24F0910103
危险品化学品经营许可证（带存储）