Protein Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.
Post-translational
Phosphorylated upon DNA damage, probably by ATM or ATR. Dephosphorylated by PTPRJ. The tyrosine phosphorylation on Tyr-398 and Tyr-402 reduces its ability to interact with TJP1.
宿主种属
兔(Rabbit)
特异性
OCLN
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Occludin (AA 1-36)
Recombinant Occludin Antibody (Ab119129) - Western Blot All lanes: Recombinant Occludin Antibody (Ab119129) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 59 kDa Observed band size: 67, 58, 54 kDa Recombinant Occludin Antibody (Ab119129) recognizes different isoforms of Occludin. Exposure time: 60.0 s
Recombinant Occludin Antibody (Ab119129) - Western Blot All lanes: Recombinant Occludin Antibody (Ab119129) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 59 kDa Observed band size: 58, 45 kDa Recombinant Occludin Antibody (Ab119129) recognizes different isoforms of Occludin. Exposure time: 100.0 s
ZJ25F0116574
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