纤溶酶 来源于人血浆

CAS: 9001-90-5 货号: np001029 分子量: 81000
有货
级别和纯度: 天然 ? 天然型(Native)—— 处于天然(非重组、非变性)形态的蛋白/生物分子。当需要天然结构和活性时使用。 EnzymoPure™ ? EnzymoPure™ —— 阿拉丁的高质量酶解决方案系列。当酶纯度和明确活性决定检测或工艺性能时使用。 ≥90%(SDS-PAGE) ≥15 U/mg protein; Protein concentration: 见COA
Accession #
P00747
生物活性
≥15 U/mg protein
★
规格
库存
价格
数量
50μg
np001029-50μg
现货 Stock Image
¥599.90
250μg
np001029-250μg
现货 Stock Image
¥1,699.90
500μg
np001029-500μg
期货 Stock Image
¥2,999.90
1mg
np001029-1mg
现货 Stock Image
¥5,599.90
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为什么选择此级别

EnzymoPure™,天然 级 提供 ≥90%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

概述

纤溶酶在纤维蛋白溶解、纤维蛋白原溶解以及补体级联反应中发挥作用。这种蛋白酶是通过使用链激酶激活人血浆纤溶酶原而制备的。
消光系数:1.71
所用血浆经 FDA 要求的检测显示,乙型肝炎表面抗原(HBsAg)、抗丙型肝炎病毒(抗 - HCV)、抗乙型肝炎核心抗体(抗 - HBc)均为阴性,且抗人类免疫缺陷病毒 1 型和 2 型(抗 - HIV 1 & 2)也为阴性。

Plasmin functions in fibrinolysis, fibrinogenolysis, as well as in the complement cascade. This protease has been prepared by using streptokinase to activate human plasma plasminogen.

Extinction Coefficient: 1.71  
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

规格

产品名称
纤溶酶 来源于人血浆
别名
纤维蛋白溶酶
英文别名
Fibrinolysin | fibrinase | PLG | HAE4
规格或纯度
天然,EnzymoPure™,≥90%(SDS-PAGE),≥15 U/mg protein; Protein concentration: 见COA
生化机理
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1, C4 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells2 PublicationsAngiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.1 Publication(Microbial infection) ENO/enoloase from parasite P.falciparum (strain NF54) interacts with PLG present in the mosquito blood meal to promote the invasion of the mosquito midgut by the parasite ookinete. The catalytic active form, plasmin, is essential for the invasion of the mosquito midgut. (Microbial infection) Binds to OspC on the surface of B.burgdorferi cells, possibly conferring an extracellular protease activity on the bacteria that allows it to traverse host tissue.1 Publication(Microbial infection) Interacts with dengue virus type 2 particles. Enhances dengue virus type 2 infection in Aedes aegypti mosquito midgut by increasing midgut internalization, resulting in higher infection rates and viral dissemination in mosquitoes.
生物活性
≥15 U/mg protein
种属
人(Human)
来源
天然
预测分子量
81 kDa
CAS编号和信息
9001-90-5
酶学委员会编号
EC 3.4.21.7
分子类型
酶
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
100 mM Sodium phosphate, 1 mM 6-aminohexanoic acid, 25% Glycerol, pH 7.3
浓度
≥15 U/mg protein; Protein concentration: 见COA
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
长期储存-80℃(大于1年); 复溶后建议分装,避免反复冻融。
单位定义
One unit is defined as the amount of enzyme that hydrolyzes one umole of tosyl-Gly-Pro-Lys-pNA per minute at 25°C, pH 7.8.  Note: One unit=1.25 CU.

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

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✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

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📊 产品数据表

产品规格和应用的快速参考摘要。

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🔬 规格说明书

该级别的完整质量属性和验收标准。

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高级数据

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找到12个结果

批号(Lot Number) 证书类型 货号
ZJ26F0939150 分析证书 np001029
ZJ26F0939149 分析证书 np001029
ZJ26F0939148 分析证书 np001029
ZJ26F0535516 分析证书 np001029
ZJ26F0535515 分析证书 np001029
ZJ26F0535514 分析证书 np001029
ZJ26F0131262 分析证书 np001029
ZJ26F0131263 分析证书 np001029
ZJ26F0131264 分析证书 np001029
ZJ25F0928130 分析证书 np001029
ZJ25F0928129 分析证书 np001029
ZJ25F0928128 分析证书 np001029
技术文档和文章
纯净提取,智慧溶剂:天然提取试剂实践手册
Clean Extracts, Smart Solvents: The Natural Extraction Reagent Playbook
抑肽酶技术综述:结构特征、作用机制与应用
A Technical Review of Aprotinin: Structural Features, Mechanisms of Action, and Applications
蛋白酶在呼吸系统与血管系统疾病中的作用与机制
Roles and Mechanisms of Proteases in Respiratory and Vascular Diseases
止血、纤溶与血管稳态中的蛋白酶功能体系及调控逻辑
Proteinase Functional Systems and Regulatory Logic in Hemostasis, Fibrinolysis, and Vascular Homeostasis
纤溶活性蛋白酶研究方法与应用: 血栓溶解、纤维蛋白降解和抗凝评价
Research Methods and Applications of Fibrinolytic Proteases: Thrombolysis, Fibrin Degradation, and Anticoagulant Evaluation
纤溶系统激活因子的作用机制、功能差异与溶栓应用
Mechanisms of Action, Functional Differences, and Thrombolytic Applications of Fibrinolytic System Activators
冰冻组织切片制备及切片冻存操作规程
Standard Operating Procedure for Frozen Tissue Section Preparation and Section Storage
内肽酶与外肽酶的功能差异及其在疾病机制研究中的应用
Functional Differences Between Endopeptidases and Exopeptidases and Their Applications in Disease Mechanism Research
传明酸在色斑护理中的作用机制:从纤溶酶系统到炎症促黑信号调节
Mechanism of Action of Tranexamic Acid in Pigmentation Care: From the Plasmin System to Regulation of Inflammation-Driven Pro-Melanogenic Signaling
丝氨酸内切蛋白酶的催化机制、分类特征与实验应用
Catalytic Mechanisms, Classification Characteristics, and Experimental Applications of Serine Endopeptidases
溶液计算器