Rabbit anti Human MMP2 Antibody, Recombinant, could be used for WB, IHC and so on.
规格
产品名称
Recombinant MMP2 Antibody
别名
Anti-MMP2抗体 | MMP2抗体 | MMP2 重组抗体
英文别名
72 kDa gelatinase | CLG4 | CLG4A72 kDa type IV collagenase | collagenase type IV-A | EC 3.4.24 | EC 3.4.24.24 | Gelatinase A | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase) | matrix metalloproteinase 2 (gelatinase A,
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly- -Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
宿主种属
兔(Rabbit)
特异性
MMP2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human MMP2 (AA 100-139)
阳性对照
WB, Mouse liver lysates. IHC: Human breast adenocarcinoma tissue.
Recombinant MMP2 Antibody (Ab115653) - Western Blot All lanes: Recombinant MMP2 Antibody (Ab115653) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution Predicted band size: 74 kDa Observed band size: 61 kDa Exposure time: 1.7 s
Recombinant MMP2 Antibody (Ab115653) - IHC Immunohistochemical analysis of paraffin-embedded human breast adenocarcinoma, using Recombinant MMP2 Antibody (Ab115653).
ZJ25F0319391
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