Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
宿主种属
兔(Rabbit)
特异性
CD274
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human PD L1 (AA 200-290).
阳性对照
WB: Mouse spleen, Ramos, THP-1, A375, MDA-MB-231 and C6 lysates. IHC: Human thymoma tissue.
Recombinant PD-L1 Antibody (Ab121009) - Western Blot All lanes: Recombinant PD-L1 Antibody (Ab121009) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 33 kDa Observed band size: 41 kDa Exposure time: 19.5 s
Recombinant PD-L1 Antibody (Ab121009) - Western Blot All lanes: Recombinant PD-L1 Antibody (Ab121009) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 33 kDa Observed band size: 41 kDa Exposure time: 56.5 s
Recombinant PD-L1 Antibody (Ab121009) - IHC Immunohistochemistry analysis of paraffin-embedded human thymoma tissue labelling PD-L1 with Recombinant PD-L1 Antibody (Ab121009) at 1/100 dilution.