概述规格名称和识别符技术文档高级数据系统学分类三维结构质检证书（CoA,COO,BSE/TSE 和分析图谱) 化学和物理性质安全和危险性（GHS）此产品的引用文献技术文档和文章引用文献溶液计算器

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为什么选择此级别

，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

室温。常规运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 34 篇同行评审文献引用。

概述

IBMX (3-Isobutyl-1-methylxanthine) (GMP) 是 GMP 级别的 IBMX。GMP 级别的小分子可用做细胞疗法中的辅助试剂。IBMX 是广谱的磷酸二酯酶 (PDE) 抑制剂。

IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor.

规格

英文名称

IBMX

储存条件

室温

运输条件

常规运输

名称和识别符

EC号

249-259-3

分子类型

小分子

IUPAC Name

1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione

INCHI

1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)

InChi Key

APIXJSLKIYYUKG-UHFFFAOYSA-N

Smiles

CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2

Isomeric SMILES

CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2

分子量

222.24

Beilstein号

247859

Reaxy-Rn

247859

Reaxys-RN link address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=247859&ln=

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

系统学分类

分类树（Taxonomy Tree）

界（kingdom) 有机化合物
- 超类（Superclass) 有机杂环化合物
  - 类（Class) 咪唑并嘧啶类
    - 亚类（Subclass）嘌呤和嘌呤衍生物

界（kingdom)	有机化合物
超类（Superclass)	有机杂环化合物
类（Class)	咪唑并嘧啶类
亚类（Subclass）	嘌呤和嘌呤衍生物
中间层级节点（Intermediate Tree Nodes）	暂无
直接上位类(Direct Parent)	黄嘌呤
其他上位类（Alternative Parents）	6-氧嘌呤生物碱及其衍生物嘧啶酮类乙烯基酰胺咪唑类杂芳族化合物尿素内酰胺类氮杂环化合物有机光子化合物有机氧化合物有机氮化合物有机氧化物碳氢化合物衍生物
分子骨架（Molecular Framework)	芳香族杂多环化合物
取代基（Substituents）	6-羰基嘌呤 - 生物碱或其衍生物 - 芳香族杂多环化合物 - 氮杂环 - 吡唑 - 杂芳香族化合物 - 烃衍生物 - 咪唑 - 肟 - 有机硝基化合物 - 有机氧化物 - 有机氧化合物 - 有机氮化合物 - 有机氧化合物 - 有机氮化合物 - 嘌呤酮 - 嘧啶 - 嘧啶酮 - 脲 - 乙烯酰胺 - 黄酮
描述（Description）	该化合物属于黄嘌呤类有机化合物。这类嘌呤衍生物在嘌呤骨架的2位和6位碳原子上共轭连接酮基团。
外部描述符（External Descriptors）	a small molecule

三维结构

交互式化学结构模型

球棍
棍棒
线框模型
空间填充
显示氢气
动画

化学和物理性质

熔点

200-203°C

安全和危险性（GHS）

象形图

GHS07

信号词

警告

危险声明

H302: 吞食有害

预防措施声明

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P330: 漱口

P501: 将内容物/容器处理到。。。

P301+P317: 如果被吞咽：请寻求医疗帮助。

WGK Germany

RTECS

ZD8500000

个人防护装备

dust mask type N95 (US),Eyeshields,Faceshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

技术文档和文章

GMP

目录：阿拉丁试剂的规格、级别和纯度

探索主题:

GMP

目录：阿拉丁试剂的规格、级别和纯度

探索主题:

GMP

尿促卵泡素（uFSH）：来源特征、分子性质与科研应用体系

目录：技术文章

探索主题:

糖基化 uFSH FSH FSHR cAMP/PKA β-arrestin 尿促卵泡素糖蛋白激素等电点异质性偏向性信号颗粒细胞支持细胞类固醇生成体外卵泡培养

Urinary Follicle-Stimulating Hormone (uFSH): Source Attributes, Molecular Properties, and Research Application Frameworks

目录：技术文章

探索主题:

Glycosylation urinary follicle-stimulating hormone uFSH FSH FSHR glycoprotein hormone isoelectric heterogeneity cAMP/PKA β-arrestin biased signaling granulosa cell Sertoli cell steroidogenesis in vitro follicle culture

肾上腺髓质素（Adrenomedullin，ADM）：多系统血管活性肽的分子特征、信号机制与研究及转化应用

目录：技术文章

探索主题:

生物标志物 adrenomedullin ADM MR-proADM CLR RAMP2 RAMP3 cAMP 肾上腺髓质素内皮屏障微循环血管舒张 NO 脓毒症心力衰竭肺动脉高压

Adrenomedullin (ADM): Molecular Features, Signaling Mechanisms, and Research and Translational Applications of a Multisystem Vasoactive Peptide

目录：技术文章

探索主题:

adrenomedullin ADM MR-proADM CLR RAMP2 RAMP3 endothelial barrier microcirculation vasodilation cAMP

法莫替丁：理化特征、作用机制与科研应用要点

目录：技术文章

探索主题:

胃蛋白酶 cAMP PK/PD 法莫替丁 Famotidine H2受体拮抗剂胃酸分泌 pH依赖吸收肾排泄组织胺信号

Famotidine: Physicochemical Features, Mechanism of Action, and Key Points for Research Applications

目录：技术文章

探索主题:

Pepsin cAMP PK/PD Famotidine H2-receptor antagonist gastric acid secretion pH-dependent absorption renal excretion histamine signaling

甘油和甘油三酯含量检测的原理、常用方法与应用要点综述

目录：技术文章

探索主题:

质谱分析色谱分析脂肪酶甘油三酯方法学规范甘油甘油激酶甘油磷酸氧化酶酶法检测

Review of the Principles, Common Methods, and Key Application Considerations for the Determination of Glycerol and Triglyceride Contents

目录：技术文章

探索主题:

lipase Methodological standardization Enzymatic Assay Glycerol Triglyceride Glycerol Kinase Glycerol Phosphate Oxidase Chromatographic Analysis Mass Spectrometric Analysis

糖蛋白激素家族的分子特征、信号偏向性与体内动力学

目录：技术文章

探索主题:

糖基化 FSH 糖蛋白激素 LH hCG TSH 共同α亚基特异β亚基信号偏向性体内动力学

Glycoprotein Hormone Family: Molecular Features, Signaling Bias, and In Vivo Pharmacokinetics

目录：技术文章

探索主题:

Glycosylation Pharmacokinetics FSH LH hCG TSH Glycoprotein hormones Common α-subunit Specific β-subunit Signaling bias

环核苷酸信号通路与第二信使调控机制

目录：技术文章

探索主题:

环核苷酸环磷酸腺苷环磷酸鸟苷环化酶磷酸二酯酶效应蛋白支架蛋白

Cyclic Nucleotide Signaling Pathways and Second Messenger Regulatory Mechanisms

目录：技术文章

探索主题:

Cyclic nucleotides Cyclic adenosine monophosphate Cyclic guanosine monophosphate Cyclases Phosphodiesterases Effector proteins Scaffold proteins

神经元信号转导机制与疾病研究

目录：技术文章

探索主题:

Neuronal Signal Transduction Mechanisms and Disease Research

目录：技术文章

探索主题:

Endocrinology/Hormones（内分泌与激素）在代谢调控、生殖功能与疾病研究中的应用

目录：技术文章

探索主题:

Hormones 胰岛素 HPA轴 GPCR 内分泌激素 Endocrinology 甲状腺激素类固醇激素性激素

Applications of Endocrinology/Hormones in Metabolic Regulation, Reproductive Function, and Disease Research

目录：技术文章

探索主题:

Hormones Insulin HPA axis GPCR Endocrinology thyroid hormone steroid hormone sex hormone

GLP-1R、GIPR与GCGR在肥胖症和2型糖尿病代谢调控及多受体激动剂治疗中的作用

目录：技术文章

探索主题:

能量代谢 GLP-1R GIPR GCGR 肥胖症 2型糖尿病肠促胰素胰高血糖素双重受体激动剂三重受体激动剂

Roles of GLP-1R, GIPR, and GCGR in Metabolic Regulation of Obesity and Type 2 Diabetes and in Multi-Receptor Agonist Therapy

目录：技术文章

探索主题:

Obesity energy metabolism GLP-1R GIPR GCGR type 2 diabetes incretin glucagon dual receptor agonist triple receptor agonist

熊果苷如何调节黑色素生成：α/β异头构型与酪氨酸酶作用

目录：技术文章

探索主题:

黑色素熊果苷

How Arbutin Regulates Melanin Production: α/β Anomeric Configuration and Tyrosinase Action

目录：技术文章

探索主题:

Melanin Arbutin

天然产物调控脂肪褐变的分子机制

目录：技术文章

探索主题:

天然产物 AMPK 脂肪褐变白色脂肪组织 UCP1 PGC-1α Hyperforin 颤抖性产热

Molecular Mechanisms by Which Natural Products Regulate Adipose Browning

目录：技术文章

探索主题:

Natural products AMPK UCP1 PGC-1α Hyperforin adipose browning white adipose tissue non-shivering thermogenesis

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Ling Yang, Linzi Li, Qian Lu, Lingfeng Li, Chun Xie, Fakun Jiang, Hongbing Li, Ai Zhao, Qian Wang, Wenyong Xiong. (2023) Alisol B blocks the development of HFD-induced obesity by triggering the LKB1-AMPK signaling in subcutaneous adipose tissue. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:37536624] [10.1016/j.ejphar.2023.175942]
2. Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun. (2023) Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis. Molecular Medicine Reports, 28 (3): (1-14). [PMID:37449526] [10.3892/mmr.2023.13050]
3. Xinyan Tao, Yuan Liu, Zhenhua Ding, Shuang Xie, Wenxiong Cao, Xiaohong Li. (2023) Injectable cell-targeting fiber rods to promote lipolysis and regulate inflammation for obesity treatment. Biomaterials Science, [PMID:37432672] [10.1039/D3BM00619K]
4. Yawei Kong, Jianpeng Ao, Qiushu Chen, Wenhua Su, Yinping Zhao, Yiyan Fei, Jiong Ma, Minbiao Ji, Lan Mi. (2023) Evaluating Differentiation Status of Mesenchymal Stem Cells by Label-Free Microscopy System and Machine Learning. Cells, 12 (11): (1524). [PMID:37296645] [10.3390/cells12111524]
5. Gao Rongyin, Zhang Ximei, Zou Kun, Meng Duo, Lv Jinpeng. (2023) Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway. Frontiers in Pharmacology, [PMID:36814484] [10.3389/fphar.2023.1081030]
6. Xiaoxue Ren, Xiaoting Gao, Yicheng Cheng, Lingxia Xie, Liping Tong, Wei Li, Paul K. Chu, Huaiyu Wang. (2023) Maintenance of multipotency of bone marrow mesenchymal stem cells on poly(ε-caprolactone) nanoneedle arrays through the enhancement of cell-cell interaction. Frontiers in Bioengineering and Biotechnology, [PMID:36698633] [10.3389/fbioe.2022.1076345]
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17. Fiorency Santoso, Bonifasius Putera Sampurna, Yu-Heng Lai, Sung-Tzu Liang, Erwei Hao, Jung-Ren Chen, Chung-Der Hsiao. (2019) Development of a Simple ImageJ-Based Method for Dynamic Blood Flow Tracking in Zebrafish Embryos and Its Application in Drug Toxicity Evaluation. Inventions, 4 (4): (65). [10.3390/inventions4040065]
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19. Kaimin Wu, Ruiyi Zhang, Yanhui Lu, Lulu Wen, Yanfei Li, Ranran Duan, Yaobing Yao, Yanjie Jia. (2019) Lin28B regulates the fate of grafted mesenchymal stem cells and enhances their protective effects against Alzheimer's disease by upregulating IGF-2. JOURNAL OF CELLULAR PHYSIOLOGY, 234 (12): (21860-21876). [PMID:31066045] [10.1002/jcp.28750]
20. Zhang Kaina, Zeng Ke, Shen Congcong, Tian Shiyu, Yang Minghui. (2018) Determination of protein kinase A activity and inhibition by using hydroxyapatite nanoparticles as a fluorescent probe. MICROCHIMICA ACTA, 185 (4): (1-7). [PMID:29594552] [10.1007/s00604-018-2754-1]
21. Qian Wang, Shuang-ting Wang, Xin Yang, Pan-pan You, Wen Zhang. (2015) Myricetin suppresses differentiation of 3 T3-L1 preadipocytes and enhances lipolysis in adipocytes. NUTRITION RESEARCH, [PMID:25724338] [10.1016/j.nutres.2014.12.009]
22. Xiaoyuan Yan, Na An, Zeying Zhang, Qiujing Qiu, Di Yang, Penggong Wei, Xiyue Zhang, Lihong Qiu, Jiajie Guo. (2024) Graphene Oxide Quantum Dots-Preactivated Dental Pulp Stem Cells/GelMA Facilitates Mitophagy-Regulated Bone Regeneration. International Journal of Nanomedicine, [PMID:39381026] [10.2147/IJN.S480979]
23. An Na, Yan Xiaoyuan, Qiu Qiujing, Zhang Zeying, Zhang Xiyue, Zheng Bowen, Zhao Zhenjin, Guo Jiajie, Liu Yi. (2024) Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation. JOURNAL OF NANOBIOTECHNOLOGY, 22 (1): (1-20). [PMID:38539195] [10.1186/s12951-024-02422-7]
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28. Mingzhi Luo, Peili Yu, Kai Ni, Yang Jin, Lei Liu, Jingjing Li, Yan Pan, Linhong Deng. (2020) Sanguinarine Rapidly Relaxes Rat Airway Smooth Muscle Cells Dependent on TAS2R Signaling. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 43 (7): (1027-1034). [PMID:32404582] [10.1248/bpb.b19-00825]
29. Longyan Yang, Ruili Yin, Ziyu Shan, Anqi Feng, Kun Li, Yan Wang, Ke Yu, Yongsong Xu, Lin Mao, Jianan Lang, Baoyu Zhang, Dong Zhao. (2025) Adipocyte-secreted ANGPTL2 promotes hyperuricemia through inhibiting AKT/ABCG2 signaling. FREE RADICAL BIOLOGY AND MEDICINE, [PMID:40180020] [10.1016/j.freeradbiomed.2025.03.048]
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31. Lei Zhou, Yuwen Jiao, Jiaming Xue, Xiaoqiang Zhan, Dongmei Wang, Liming Tang. (2025) LRRFIP1 Inhibits White Adipocyte Differentiation by Suppressing the E2F6/C/EBPα Axis. Diabetes & Metabolism Journal, [PMID:41224206] [10.4093/dmj.2025.0178]
32. Yuting Chen, Jie Min, Xiali Yu, Haixiang Ni, Yamei Jin. (2025) Danshenol A Mediates the Proliferation and Differentiation of Adipocytes in Thyroid-Associated Ophthalmopathy. Endocrine Metabolic & Immune Disorders-Drug Targets, 26 (1): (E18715303382831). [PMID:40734440] [10.2174/0118715303382831250712200617]
33. Mao Congyang, Jin Wanyu, Dou Limeng, Guo Tong, Huang Jin, Wang Yi, Liu Xiangmei, Wu Shuilin, Qiao Wei, Xiang Yiming, Zhu Yizhou, Wu Jun, Yeung Kelvin Wai Kwok. (2026) Bioengineered ROS-tolerant probiotic reshapes gut microbiota-host axis to ameliorate type 2 diabetes in male mice. Nature Communications, [10.1038/s41467-026-70138-3]
34. Jing Li, Yang-Chi-Dung Lin, Hsi-Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien-Da Huang. (2026) Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects. PHYTOTHERAPY RESEARCH, [PMID:42457559] [10.1002/ptr.70407]