计算溶液所需的质量、体积或浓度。
聚(乙二醇)(PEG)是非离子型亲水聚合物,可获得不同的分子量形式。它有助于蛋白和核酸的纯化和晶体生长。PEG和葡聚糖一起产生生物材料纯化所需的聚合物双水相体系。PEG还可与细胞膜相互作用,从而促进细胞融合。它具有隐身效果,以及延长的血液循环和出色的生物相容性。PEG能过通过刺激补体途径引起超敏反应。
应用
聚乙二醇用于:
1,作为制备液体干燥剂溶液的成分
2,作为蛋白质结晶中的沉淀剂和添加剂,
3,作为代表性的生物相容性聚合物,可在分子水平上解释其与细胞系统的相互作用
Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. It exhibitsstealth effect, prolonged blood circulation and excellent biocompatibility. PEG has an ability to elicit hypersensitivity reactions via stimulating complement pathway.
Application
Poly(ethylene glycol) has been used:
1,as a constituent in the preparation of liquid desiccant solutions
2,as a precipitating agent and additive in protein crystallization
3,as a representative biocompatible polymer to decipher its interactions with cellular system at molecular level
| pH | 5.5-7.0 (25 °C, 50 mg/mL in H2O) |
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