计算溶液所需的质量、体积或浓度。
聚乙二醇(PEG)是乙二醇聚合物,具有亲水性。PEG结构灵活并且具有高水合能力。由于PEG具有生物相容性并且结构中不存在空间位阻。它是非免疫原性且安全的。PEG结合改善了糖尿病药物格列齐特的溶解度和溶出度。PEG被广泛用作生物化学和分子生物学实验的试剂。它被用于碳纳米管官能化。
应用
聚乙二醇已被用作:
1,小麦原生质体分离和转化缓冲液的组分
2,悬浮细胞培养物的添加剂
3,酵母转化缓冲液的组分
4,半胱氨酸蛋白酶ATG4B结晶化缓冲液的组分
Poly(ethylene glycol) (PEG) is a polymer ethylene glycol units and is hydrophilic in nature. PEG is structurally flexible and has high hydration capacity. PEG is biocompatible and is devoid of steric hindrances in its structure.It is nonimmunogenic and safe. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. PEG is widely used as a reagent in biochemistry and molecular biology experiments. It is used in carbon nanotube functionalization.
Application
Poly(ethylene glycol) has been used:
1,as a component of wheat protoplast isolation and transformation buffer
2,as an additive in suspension cell culture
3,as a component of yeast transformation buffer
4,as a component of crystallization buffer in cysteine protease ATG4B crystallization
| pH | 5.5-7.0 (25 °C, 50 mg/mL in H2O) |
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