基本描述

别名	聚氧乙烯山梨糖醇酐单月桂酸酯 \| 聚氧乙烯脱水山梨醇单月桂酸酯 \| 聚氧乙烯山梨糖醇酐单月桂酸酯 \| 聚氧乙烯脱水山梨醇单月桂酸酯
英文别名	POE (6) sorbitol monolaurate \| Tween(R) 20 \| 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate \| SCHEMBL118527 \| Tween 40 (TN) \| 1052273-76-3 \| 2-(2-(3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)eth
规格或纯度	粘性液体
英文名称	TWEEN ® 20
法律信息	TWEEN is a registered trademark of Croda International PLC
储存温度	室温
运输条件	常规运输
产品介绍	吐温20是一种基于天然脂肪酸（月桂酸）的乙氧基化（20）山梨糖醇酯。这乙氧基化物在形成油水型乳化剂时非常高效，特别是和非乙氧基化衍生物司班20结合使用时尤为如此。化学基团：非离子表面活性剂 - 脱水山梨醇酯和乙氧基化脱水山梨醇酯 Form @ 25oC Clear yellow liquid HLB 16.7 产品生产厂家：英国禾大（Croda）非离子型表面活性剂。气相色谱固定液(最高使用温度120℃)分离分析挥发油、脂肪酸酯、醇、酮和卤化物。水溶性乳化剂。加溶剂。纺织工业用抗静电剂和纤维润滑剂产品应用 TWEEN 20作为组分已用于： Western blotting中的洗涤和封闭缓冲液免疫组化中的封闭缓冲液 ELISA（酶联免疫吸附测定）中的洗涤缓冲液 PCR（聚合酶链反应）中的反应混合液 TWEEN 20是一种广泛用于生化应用的非离子型去污剂。它已被作为乳化剂用于稳定的水包油乳液的制备。TWEEN 20已用于膜的预提取以去除外周蛋白（以2％用于膜结合蛋白的提取）。通常0.05%浓度的TWEEN 20在基于膜的免疫检测中被用作封闭剂。0.005至0.5%的TWEEN 20可用于裂解哺乳动物细胞。非离子洗涤剂 Tween 20 is an ethoxylated (20) sorbitan ester based on a natural fatty acid (lauric acid). This ethoxylate is highly effective at forming O/W emulsions, particularly when used in combination with its non-ethoxylated derivative, Span 20. Chemical group Nonionic Surfactants - Sorbitan Esters and Ethoxylated Sorbitan Esters Form @ 25oC Clear yellow liquid HLB 16.7 Manufacturer：Croda Non-ionic detergent ECO TWEEN® 20, also known as Polyoxyethylenesorbitan monolaurate, is a bio-based, nonionic detergent manufactured from a natural fatty acid. This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, protein extraction, nuclei isolation and cell fractionation. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation". TWEEN 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached. Product Application TWEEN 20 has been used as a component of: washing buffer and blocking buffer in Western blotting blocking buffer in immunohistochemistry washing buffer in ELISA (enzyme linked immunosorbent assay) reaction mixture in PCR (polymerase chain reaction) TWEEN 20 is a nonionic detergent widely used in biochemical applications. It has been used as an emulsifying agent for the preparation of stable oil-in-water emulsions. TWEEN 20 has been used in pre-extraction of membranes to remove peripheral proteins (used at 2% for extraction of membrane-bound proteins). TWEEN 20 has been used as a blocking agent for membrane based immunoassays at a typical concentration of 0.05%. TWEEN 20 can be used for lysing mammalian cells at a concentration of 0.005 to 0.5%.

AI解读

关联靶点（其它种属）

Mus musculus (284745 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

分子类型	小分子
IUPAC Name	2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
INCHI	InChI=1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChi Key	HMFKFHLTUCJZJO-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
Isomeric SMILES	CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
WGK Germany	1
RTECS	TR7400000
PubChem CID	443314

化学和物理性质

溶解性	可溶于水；可溶于二恶烷、乙醇、甲醇
密度	1.11
敏感性	对湿度敏感；热敏感
折光率	1.4685-1.4715
闪点(℃)	>149℃
沸点	100°C
熔点	-14 °C
分子量	522.700 g/mol
XLogP3	2.500
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	10
可旋转键计数Rotatable Bond Count	26
精确质量Exact Mass	522.34 Da
单同位素质量Monoisotopic Mass	522.34 Da
拓扑极表面积Topological Polar Surface Area	133.000 Å²
重原子数Heavy Atom Count	36
形式电荷Formal Charge	0
复杂度Complexity	507.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	4
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	1
RTECS	TR7400000
个人防护装备	Eyeshields,Gloves

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找到138个结果

批号(Lot Number)	证书类型	日期	货号
B2526098	分析证书	25-02-17	T104863
C2510010	分析证书	25-02-17	T104863
C2513200	分析证书	25-02-17	T104863
D2503215	分析证书	24-10-16	T104863
D2503217	分析证书	24-10-16	T104863
K2413150	分析证书	24-10-16	T104863
K2413152	分析证书	24-10-16	T104863
K2413213	分析证书	24-10-16	T104863
K2422218	分析证书	24-10-16	T104863
K2422219	分析证书	24-10-16	T104863
J2412349	分析证书	24-09-09	T104863
J2412350	分析证书	24-09-09	T104863
J2412392	分析证书	24-09-09	T104863
K2401178	分析证书	24-09-09	T104863
K2401179	分析证书	24-09-09	T104863
K2401258	分析证书	24-09-09	T104863
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I2418224	分析证书	24-08-28	T104863
I2418225	分析证书	24-08-28	T104863
J2422330	分析证书	24-08-28	T104863
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J2423154	分析证书	24-08-28	T104863
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G2411071	分析证书	23-08-25	T104863
G2418079	分析证书	23-08-25	T104863
H2331323	分析证书	23-08-25	T104863
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G23211049	分析证书	23-06-15	T104863
F23171058	分析证书	23-06-15	T104863
C2317581	分析证书	23-03-10	T104863
C2317582	分析证书	23-03-10	T104863
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B23211021	分析证书	23-02-09	T104863
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B23211061	分析证书	23-02-09	T104863
B23211020	分析证书	23-02-09	T104863
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B2314671	分析证书	23-02-09	T104863
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B2310087	分析证书	23-02-01	T104863
L2214964	分析证书	22-12-05	T104863
L2215186	分析证书	22-12-05	T104863
J2228062	分析证书	22-10-18	T104863
J2228063	分析证书	22-10-18	T104863
J2228064	分析证书	22-10-18	T104863
H2203237	分析证书	22-07-28	T104863
H2203238	分析证书	22-07-28	T104863
H2203239	分析证书	22-07-28	T104863
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G2214630	分析证书	22-06-21	T104863
G2214652	分析证书	22-06-21	T104863
G2214666	分析证书	22-06-21	T104863
G2214670	分析证书	22-06-21	T104863
A2303334	分析证书	22-06-21	T104863
G2201575	分析证书	22-06-21	T104863
G2201576	分析证书	22-06-21	T104863
G2201577	分析证书	22-06-21	T104863
G2201636	分析证书	22-06-21	T104863
F2224011	分析证书	22-06-21	T104863
F2224012	分析证书	22-06-21	T104863
F2224009	分析证书	22-06-21	T104863
F2224010	分析证书	22-06-21	T104863
F2224007	分析证书	22-06-21	T104863
F2224008	分析证书	22-06-21	T104863
C2208082	分析证书	22-03-19	T104863
C2208093	分析证书	22-03-19	T104863
C2226734	分析证书	22-03-14	T104863
C2226735	分析证书	22-03-14	T104863
C2226736	分析证书	22-03-14	T104863
C2226737	分析证书	22-03-14	T104863
C2208096	分析证书	22-03-11	T104863
C2208103	分析证书	22-03-11	T104863
C2205146	分析证书	22-03-08	T104863
L2121579	分析证书	21-12-11	T104863

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溶液计算器

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