J2409893计算溶液所需的质量、体积或浓度。
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
为什么选择此级别
提供 ≥99.8% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
室温,充氩。常规运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 1643 篇同行评审文献引用。
概述
溶于水，几乎不溶于乙醇，约在50℃失去二氧化碳，热在100℃全部变为碳酸钠。在弱酸中迅速分解，其水溶液在20℃时开始分解出二氧化碳和碳酸钠，到沸点时全部分解。25℃时溶于10份水，约18℃时溶于12份水，其冷水制成的没有搅动的溶液，对酚酞试纸鲜配制的0.1mol/L水溶液pH值8.3。低毒，半数致死量(大鼠，经口)4420mg/kg。
碳酸氢钠在细胞培养应用中被广泛用作一种生理性缓冲液。 碳酸氢根<->碳酸的pKa是6.4 碳酸氢根<->碳酸盐的pKs是10.3。 碳酸氢钠具有两个pKa，6.4和10.3。 它在体外应用中被广泛用作一种生理性缓冲液。
应用
碳酸氢钠已用于：
作为体外熟化、受精和培养（IVMFC）过程中牛胚胎培养系统的一种成分
作为牛微血管内皮细胞培养过程中Dulbecco′s modified Eagle′s培养基和Ham′s 营养混合物F-121:1混合物中的一种成分
作为从人胚胎干细胞中进行多巴胺神经元分离过程中使用的ITS（胰岛素转铁蛋白和亚硒酸盐）培养基中的一种成分
作为用于人胚肾细胞的细胞培养基中的一种成分
作为用于稀释精液的Beltsville解冻溶液中的一种成分
Sodium bicarbonate is a commonly used laboratory chemical. The compound can react with both acids and bases, therefore it can be used as a neutralizer. When reacting with bases the compound forms carbonates. Sodium bicarbonate may be used to remove or wash acidic impurities from a crude liquid to yield a purer sample. Sodium bicarbonate reacts with the carboxyl groups to give a fast-forming and effervescent CO2 formation which has been used to test for the presence of carboxylic groups in proteins. Sodium bicarbonate has been observed to significantly decrease serum potassium levels as well as increase blood pH and bicarbonate concentration. The compound has been recorded to decrease the duration of peripheral nerve block in rats when when added to Lidocaine.
A commonly used laboratory pH neutralizer that reacts with acids and bases.
规格
别名
焙碱
英文别名
Baking soda | SODIUM BICARBONATE [USP MONOGRAPH] | SODIUM BICARBONATE COMPONENT OF NORMOCARB | Sodium bicarbonate in plastic container | Acidosan | Natrii hydrogencarbonas | Natrum bicarbonicum | Neut (TN) | PF 573228 pound>>PF573228 | Sodium bicarbonate
规格或纯度
≥99.8%
英文名称
Sodium bicarbonate
储存条件
室温,充氩
运输条件
常规运输
纯度
≥99.8%
名称和识别符
EC号
205-633-8
分子类型
小分子
IUPAC Name
sodium;hydrogen carbonate
INCHI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChi Key
UIIMBOGNXHQVGW-UHFFFAOYSA-M
Smiles
C(=O)(O)[O-].[Na+]
Isomeric SMILES
C(=O)(O)[O-].[Na+]
MeSH Entry Terms
Baking Soda;Bicarbonate, Sodium;Carbonic Acid Monosodium Salt;Hydrogen Carbonate, Sodium;Soda, Baking;Sodium Bicarbonate;Sodium Hydrogen Carbonate
分子量
84.01
Beilstein号
4153970
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 有机酸及其衍生物 |
| 类（Class) | 有机碳酸及其衍生物 |
| 亚类（Subclass） | 有机碳酸 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 有机碳酸 |
| 其他上位类（Alternative Parents） | 碳酸盐 有机钠盐 有机氧化物 碳氢化合物衍生物 羰基化合物 |
| 分子骨架（Molecular Framework) | 脂肪族无环化合物 |
| 取代基（Substituents） | 脂肪族非环化合物 - 碳酸酯 - 碳酸 - 羰基 - 烃衍生物 - 有机碱金属盐 - 有机氧化物 - 有机氧化合物 - 有机盐 - 有机钠盐 - 有机氧化合物 |
| 描述（Description） | 该化合物属于有机碳酸类有机化合物。这类化合物具有碳酸官能团。 |
| 外部描述符（External Descriptors） | one-carbon compound - organic sodium salt |
三维结构
交互式化学结构模型
关联靶点（人）
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
CA1
Tclin
Carbonic anhydrase I
(13240 活性数据)
CA5A
Tclin
Carbonic anhydrase VA
(1168 活性数据)
CA9
Tclin
Carbonic anhydrase IX
(8255 活性数据)
Homo sapiens
(32628 活性数据)
CA5B
Tclin
Carbonic anhydrase V
(54 活性数据)
关联靶点（其它种属）
CA4
Carbonic anhydrase IV (1713 活性数据)
Carbonic anhydrase (69 活性数据)
Colletotrichum musae (107 活性数据)
Trypanosoma cruzi (99888 活性数据)
Fusarium verticillioides (912 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
Lasiodiplodia theobromae (193 活性数据)
Venturia inaequalis (72 活性数据)
Astrosclerin-3 (80 活性数据)
Malus domestica (19 活性数据)
Thielaviopsis paradoxa (80 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
溶解性
溶于水(50 mg/ml)，不溶于乙醇。
密度
2.16
敏感性
对湿度敏感
折光率
1.500
熔点
270°C
分子量
84.007 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count
1
氢键受体数Hydrogen Bond Acceptor Count
3
可旋转键计数Rotatable Bond Count
0
精确质量Exact Mass
83.9823 Da
单同位素质量Monoisotopic Mass
83.9823 Da
拓扑极表面积Topological Polar Surface Area
60.400 Ų
重原子数Heavy Atom Count
5
形式电荷Formal Charge
0
复杂度Complexity
33.900
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
0
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
2
安全和危险性（GHS）
RTECS
VZ0950000
质检证书（CoA,COO,BSE/TSE 和分析图谱)
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此产品的引用文献
溶液计算器
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