计算溶液所需的质量、体积或浓度。
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
为什么选择此级别
，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
避光,-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 461 篇同行评审文献引用。
概述
无气味。微有甜味。有吸湿性。与水合茚三酮反应呈黄色，被冰乙酸酸化后则显红色。易溶于水和乙醇，不溶于乙醚、丁醇和异丙醇，溶于无机酸。。水中溶解度：1623g/L (25°C)，乙醇溶解度: 67g/100mL (19°C)。
规格
别名
L-脯氨酸 | D-吡咯烷-2-羧酸
英文别名
4-07-00-02419 (Beilstein Handbook Reference) | BDBM234390 | Bis(2,4,6-trinitro-phenyl)-amin [German] | L-Proline,(S) | PROLINE (II) | 9DLQ4CIU6V | DB00172 | (2S)-proline | FEMA Number 3319 | s-proline | (-)-2-Pyrrolidinecarboxylic acid | NCGC00014017 | NS
规格或纯度
10mM in Water
英文名称
L-Proline
储存条件
避光,-80℃储存
运输条件
特低温运输
作用类型
抑制剂
名称和识别符
技术文档
高级数据
关联靶点（人）
F2
Tclin
Thrombin
(11687 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
EPHX1
Tchem
Epoxide hydrolase 1
(644 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
ACE
Tclin
Angiotensin-converting enzyme
(1423 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
GRIN1
Tclin
Glutamate (NMDA) receptor subunit zeta 1
(122 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
PDE4A
Tclin
Phosphodiesterase 4A
(1943 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
HRH3
Tclin
Histamine H3 receptor
(10389 活性数据)
KDR
Tclin
Vascular endothelial growth factor receptor 2
(20924 活性数据)
CYP2D6
Tclin
Cytochrome P450 2D6
(33882 活性数据)
CYP1A2
Tchem
Cytochrome P450 1A2
(26471 活性数据)
SLC1A4
Tbio
Neutral amino acid transporter A
(18 活性数据)
CYP2C9
Tchem
Cytochrome P450 2C9
(32119 活性数据)
CYP2C19
Tchem
Cytochrome P450 2C19
(29246 活性数据)
CYP3A4
Tclin
Cytochrome P450 3A4
(53859 活性数据)
Liver microsomes
(16955 活性数据)
LMNA
Tbio
Prelamin-A/C
(36751 活性数据)
SLC36A1
Tchem
Proton-coupled amino acid transporter 1
(102 活性数据)
SLC1A5
Tchem
Neutral amino acid transporter B(0)
(65 活性数据)
关联靶点（其它种属）
Slc25a20
Carnitine/acylcarnitine translocase (26 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
Pkm
Pyruvate kinase isozymes M1/M2 (66 活性数据)
lef
Anthrax lethal factor (7585 活性数据)
Grin1
Glutamate NMDA receptor (6467 活性数据)
Slc16a10
Monocarboxylate transporter 10 (73 活性数据)
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
Hyaloperonospora parasitica (23 活性数据)
Brassica oleracea (32 活性数据)
GAP1
General amino-acid permease GAP1 (481 活性数据)
Slc1a5
Amino acid transporter (271 活性数据)
Slc7a10
Asc-type amino acid transporter 1 (14 活性数据)
SARS-CoV-2 (38078 活性数据)
proB
Glutamate 5-kinase (13 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
敏感性
易吸潮
比旋光度
-85 ° (C=4, H2O)
熔点
228°C
分子量
115.130 g/mol
XLogP3
-2.500
氢键供体数Hydrogen Bond Donor Count
2
氢键受体数Hydrogen Bond Acceptor Count
3
可旋转键计数Rotatable Bond Count
1
精确质量Exact Mass
115.063 Da
单同位素质量Monoisotopic Mass
115.063 Da
拓扑极表面积Topological Polar Surface Area
49.300 Ų
重原子数Heavy Atom Count
8
形式电荷Formal Charge
0
复杂度Complexity
103.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
1
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
WGK Germany
1
RTECS
TW3584000
Merck Index
7780
个人防护装备
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
技术文档和文章
Peptide Basics
目录： 技术文章
防止蛋白沉淀的缓冲液添加剂
目录： 技术文章
蛋白储存常用保护剂与配方
目录： 技术文章
Chiral Amines in Asymmetric Synthesis: Role Map (A–F), a Minimal Evidence Chain, and a Research Selection Guide (with Tables 1–3)
目录： 技术文章
Pyrrolidine and Its Derivative Systems: How a Five-Membered N-Heterocycle Tunes Properties and Use Cases via “Charge State–Conformation–Functional-Group Switching” (with Tables 1–4 for Selection Navigation)
目录： 技术文章
β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention
目录： 技术文章
Silicon Reagent-Assisted Peptide Synthesis: Research Progress and Methodological Value of Peptide Bond Formation from Unprotected Substrates
目录： 技术文章
From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC
目录： 技术文章
Reassessing Trimethylaluminum: Method Design and Experimental Value of One-Pot Peptide Elongation from Unprotected Amino Acids
目录： 技术文章
Chiral Catalyst and Ligand Selection Guide: From Reaction Task to Catalytic System Screening
目录： 技术文章
Why Small Molecules Can Also Serve as Catalysts: Judging Organocatalytic Systems from Reaction Objectives and Activatable Structural Sites
目录： 技术文章
Performance Sources and Formulation Applications of Enzyme-Based Ingredients in Daily Chemical Products: Fermentation Transformation, Enzymatic Reactions, and Application Principles
目录： 技术文章
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
目录： 技术文章
How Do Collagen Peptides Act on the Skin? From Surface Hydration and Percutaneous Delivery to Fibroblasts and Collagen Homeostasis
目录： 技术文章
Anti-Photoaging Potential of Artemia Extract: UV-Induced Damage Cascades, HSP70-Related Stress Protection, and GP4G Metabolic Insights
目录： 技术文章
How Palmitoyl Pentapeptide-4 Acts on the Skin: From the KTTKS Sequence and Skin Delivery to Collagen Matrix Responses
目录： 技术文章
How Does Collagen Tripeptide Act on the Skin: Stratum Corneum Delivery, Matrix Protection, and Regulation of Collagen Homeostasis
目录： 技术文章
What Determines Collagen Function: From Triple-Helix Formation to Hierarchical Assembly, Crosslink Maturation, and Dynamic Remodeling
目录： 技术文章
Mechanisms of Retinol Action in the Skin: From Metabolic Activation and RAR/RXR-Mediated Transcriptional Regulation to Epidermal Renewal and Collagen Homeostasis
目录： 技术文章
What Is “Plant Collagen”? Distinguishing Ingredient Types, Structural Differences, Production Methods, and Skincare Effects
目录： 技术文章
The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis
目录： 技术文章
Differences Between Animal-Derived Collagen and Recombinant Collagen in Skincare: Sequence and Structure, Safety, Skin Effects, and Evidence Evaluation
目录： 技术文章
此产品的引用文献
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
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