B2421605计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
有货
为什么选择此级别
UltraBio™,超纯级 提供 ≥99.5%(RT) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
避光,室温,干燥。常规运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 4267 篇同行评审文献引用。
概述
L-抗坏血酸是一种不饱和γ-内酯环，含有与羰基相连的烯二醇构型(-COH =COH)。
应用
用于细胞培养，作为抗氧化剂和再生生育酚。
L-抗坏血酸已应用于：
用于细胞生长的成骨补充剂
作为分化介质的一个组成部分
在WS-MSCs(沃纳综合征-间充质干细胞)中研究抗坏血酸对衰老缺陷的修复作用
其他说明
蛋白质变性；通过切割与Fe-BABE偶联的单个半胱氨酸＆＃945;亚基，研究 大肠杆菌 RNA聚合酶α亚基的二聚缔合。
Gene Information
human ... SLC23A2(9962)
General Description
L-Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. It is naturally present in a variety of foods such as citrus fruits and vegetables. It is present only in minimal amount in milk.
Application
L-Ascorbic acid has been used as an antioxidant supplement in incubation solution for dissected and sliced brain sections. It has also been used as a supplement in phosphate-buffered saline (PBS) wash buffer during oxidative GFP chromophore formation.
Other Notes
Denaturation of proteins; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABE.
规格
别名
L -抗坏血酸 | 维他命C | 抗坏血病因子
英文别名
Ascorbicap | C-Long | Ferrous ascorbate | phosphorus oxichloride | Ceglion | Cenetone | Cetemican | hexamethyl-disiloxane | Ascorb | Cemagyl | Cipca | Planavit C | Secorbate | Vitacee | Ascorbicab | Scorbacid | Cecon | C-Span | Duoscorb | pentakis(chloran
规格或纯度
UltraBio™, 超纯级, ≥99.5%(RT)
英文名称
L-Ascorbic acid
生化机理
L-抗坏血酸主要具有抗氧化性能。它保护植物免受氧化应激，保护哺乳动物免受与氧化应激相关的疾病。L-抗坏血酸主要对羟基自由基、超氧化物和单线态氧起保护作用。此外，它还还原膜连接的抗氧化剂α-生育酚(氧化形式)。L-抗坏血酸增强内皮依赖性血管舒张在各种疾病，包括糖尿病，冠状动脉疾病，高血压和慢性心力衰竭。
储存条件
避光,室温,干燥
运输条件
常规运输
作用类型
抑制剂
纯度
≥99.5%(RT)
名称和识别符
PubChem SID
EC号
200-066-2
分子类型
小分子
IUPAC Name
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
INCHI
1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChi Key
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Smiles
OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
Isomeric SMILES
C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
NSC Number
UN 1648
UN Number
MeSH Entry Terms
Acid, Ascorbic;Acid, L-Ascorbic;Ascorbate, Ferrous;Ascorbate, Magnesium;Ascorbate, Sodium;Ascorbic Acid;Ascorbic Acid, Monosodium Salt;di-L-Ascorbate, Magnesium;Ferrous Ascorbate;Hybrin;L Ascorbic Acid;L-Ascorbic Acid;Magnesium Ascorbate;Magnesium Ascorbi
分子量
176.12
Beilstein号
84272
Reaxy-Rn
84272
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=84272&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 有机杂环化合物 |
| 类（Class) | 二氢呋喃 |
| 亚类（Subclass） | 呋喃酮 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 丁烯内酯 |
| 其他上位类（Alternative Parents） | 乙烯基酸 烯酸酯类 仲醇 内酯 烯二醇 1,2-二醇 氧环化合物 一元羧酸及其衍生物 伯醇 有机氧化物 碳氢化合物衍生物 羰基化合物 |
| 分子骨架（Molecular Framework) | 脂肪族杂单环化合物 |
| 取代基（Substituents） | 1,2-二醇 - 2-呋喃酮 - 羟基苯甲酸酯 - 脂肪族杂单环化合物 - α,β-不饱和羧酸酯 - 羰基 - 羧酸衍生物 - 羧酸酰胺 - 萘醌 - 乙酰基 - 烃衍生物 - L-α-氨基酸 - 单羧酸或其衍生物 - 有机氧化物 - 有机氧化合物 - 有机氧化合物 - 氧杂环 - 初级醇 - 醛基 - 乙烯基羧酸 |
| 描述（Description） | 该化合物属于丁烯内酯类有机化合物。这类化合物是二氢呋喃结构，其C2碳原子上带有羰基。 |
| 外部描述符（External Descriptors） | Water-soluble vitamins |
三维结构
交互式化学结构模型
关联靶点（人）
ADRA2B
Tclin
α-2B 肾上腺素受体(Alpha-2B adrenergic receptor)
(0 活性数据)
VDR
Tclin
Vitamin D receptor
(26531 活性数据)
Lymphoblastoid cell
(5959 活性数据)
EHMT2
Tchem
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
(93046 活性数据)
L3MBTL1
Tchem
Lethal(3)malignant brain tumor-like protein 1
(14536 活性数据)
LMNA
Tbio
Prelamin-A/C
(36751 活性数据)
GMNN
Tbio
Geminin
(128009 活性数据)
CBX1
Tbio
Chromobox protein homolog 1
(92434 活性数据)
关联靶点（其它种属）
Plasmodium falciparum (966862 活性数据)
lef
Anthrax lethal factor (7585 活性数据)
TGR
Thioredoxin glutathione reductase (28579 活性数据)
Nfe2l2
Nuclear factor erythroid 2-related factor 2 (214 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
溶解性
H2O：1M at20°C，透明，无色
敏感性
对光线敏感
比旋光度
21 ° (C=10, H2O)
熔点
190-192°C
分子量
176.120 g/mol
XLogP3
-1.600
氢键供体数Hydrogen Bond Donor Count
4
氢键受体数Hydrogen Bond Acceptor Count
6
可旋转键计数Rotatable Bond Count
2
精确质量Exact Mass
176.032 Da
单同位素质量Monoisotopic Mass
176.032 Da
拓扑极表面积Topological Polar Surface Area
107.000 Ų
重原子数Heavy Atom Count
12
形式电荷Formal Charge
0
复杂度Complexity
232.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
2
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
WGK Germany
1
RTECS
CI7650000
Class
II
Merck Index
830
个人防护装备
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
质检证书（CoA,COO,BSE/TSE 和分析图谱)
技术文档和文章
Bio-based Chemicals: From Platform Molecules to Application Scenarios — Trend Insights and Aladdin’s Product Portfolio
目录： 技术文章
Nanowires: Properties, Preparation Routes, and Process Selection (Comprehensive Analysis of Top-Down and Bottom-Up Approaches with Recommended Aladdin Reagents)
目录： 技术文章
Tyrosinase: a key regulatory enzyme in melanin synthesis and its biological and applied significance
目录： 技术文章
Installing a Redox Switch on Biomolecules: Principles, Conjugation Essentials, and an Application Guide for ATTO MB2 NHS ester
目录： 技术文章
Functions and Significance of Common Physiological and Biochemical Indices in Animals and Plants
目录： 技术文章
How Organic Acids “Stabilize a System”: Selection Logic via the pH Window, Salt Forms, and Metal-Ion Management (with a navigation guide to Tables A–E)
目录： 技术文章
Plant Omics Panorama: Workflow Frameworks and Multi-Omics Integration from Genomics to Transcriptomics, Proteomics, and Metabolomics
目录： 技术文章
Lipid Panel Testing in Research (TC, TG, HDL-C, LDL-C): Indicator System, Assay Principles, Technical Routes, and Application Overview
目录： 技术文章
Glucose Content Determination: A Systematic Review of Detection Principles, Method Validation, and Research Application Frameworks
目录： 技术文章
Chlorophyll: Structural Features, Physicochemical Properties, and Key Points for Research and Industrial Applications
目录： 技术文章
Ferulic Acid: Structural Features, Preparation Routes, and Key Points for Research Applications
目录： 技术文章
Physicochemical Properties of Diphenylamine, Analytical Applications, and a Review of Its DNA Colorimetric Reaction
目录： 技术文章
Review of Glucose-6-phosphate Dehydrogenase (G6PD): Structural Features, Metabolic Functions, and Research Applications
目录： 技术文章
Review of the Structural Characteristics, Biological Functions, and Application Advances of Lycopene
目录： 技术文章
Analytical Basis, Methodological Systems, and Quality Control for Vitamin C Content Determination
目录： 技术文章
Progress in Research on Sugar-Nucleotide Metabolism Related to Ascorbate Biosynthesis in Plants
目录： 技术文章
Coupling Mechanisms Between Terminal Reducing-Power Allocation in Photosynthetic Electron Transport and Metabolic Demand
目录： 技术文章
Research Progress on the Moonlighting Functions of Carbohydrate-Metabolic Enzymes in Replication Programs, DNA Damage Repair, and Inflammatory Activation
目录： 技术文章
Mechanisms and Experimental Applications of β-GP, Ascorbic Acid, and Dexamethasone in Osteogenic Induction Systems
目录： 技术文章
水杨酸向儿茶酚转化的酶促羟化机制
目录： 技术文章
Waterborne Resin Technology Explained: Waterborne Forms, Performance Balance, and a Technology Map
目录： 技术文章
Signal Transduction Mechanism of Graphene Biosensors: From Molecular Recognition to Electrical/Optical Signal Readout and Materials Selection
目录： 技术文章
What Is Synthetic Biology? The Industrialization Pathway from Upstream Reagent Toolchains to Biomanufacturing Applications
目录： 技术文章
Comparison of Bilirubin Detection Methods: Application Selection of the Diazo Method, Vanadate Oxidation Method, Bilirubin Oxidase Method, and HPLC
目录： 技术文章
Mechanistic Analysis of Topical Glutathione in Skincare: Cellular Redox Regulation, Skin Delivery Challenges, and SLN-Based Delivery Strategies
目录： 技术文章
Mechanism of Kojic Acid in Reducing Hyperpigmentation: From Tyrosinase Inhibition to Melanin Production Regulation
目录： 技术文章
If the DNA Sequence Remains Unchanged, Why Does Gene Expression Change? Core Mechanisms and Research Methods of Epigenetic Regulation
目录： 技术文章
The Skin Anti-Aging Mechanisms of α-Lipoic Acid: ALA/DHLA Redox Cycling, the Antioxidant Network, and Regulation of Collagen AGE Formation
目录： 技术文章
Comparison of Iron Content Detection Methods: TPTZ, 1,10-Phenanthroline, Ferrozine, 2,2'-Bipyridine, and Instrumental Analysis
目录： 技术文章
Tocopherols in the Vitamin E Family: How They Block the Chain Reaction of Lipid Peroxidation in Skin Lipids
目录： 技术文章
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
目录： 技术文章
The Dual-Targeted Skin-Brightening Mechanism of 4-MSK: Inhibiting Melanin Production and Reducing Epidermal Pigment Retention
目录： 技术文章
Antioxidant Mechanisms, Stability, and Delivery Strategies of Resveratrol in Skincare Research
目录： 技术文章
Antioxidant Mechanisms of Ferulic Acid in Skincare, Vitamin C/E Synergy, and Stable Delivery Applications
目录： 技术文章
Skin Anti-Aging Mechanisms of Carnosine and Decarboxy Carnosine: Active Carbonyl Scavenging, Oxidative-Stress Buffering, and Inhibition of Collagen Glycation Cross-Linking
目录： 技术文章
How Do Collagen Peptides Act on the Skin? From Surface Hydration and Percutaneous Delivery to Fibroblasts and Collagen Homeostasis
目录： 技术文章
Phenylethyl Resorcinol (377): Structural Characteristics, Melanogenesis-Regulating Mechanisms, and Related Applications in Formulation Research
目录： 技术文章
Anti-Photoaging Potential of Artemia Extract: UV-Induced Damage Cascades, HSP70-Related Stress Protection, and GP4G Metabolic Insights
目录： 技术文章
Regulatory Mechanisms, Research Methods, and Modification-Omics Analysis of Protein Post-Translational Modifications
目录： 技术文章
Potential Mechanisms of Tea Polyphenols in Oily, Acne-Prone Skin: Effects of EGCG on Sebum Production, Lipid Peroxidation, and Inflammatory Responses
目录： 技术文章
Mechanism of Action of Tranexamic Acid in Pigmentation Care: From the Plasmin System to Regulation of Inflammation-Driven Pro-Melanogenic Signaling
目录： 技术文章
How Palmitoyl Pentapeptide-4 Acts on the Skin: From the KTTKS Sequence and Skin Delivery to Collagen Matrix Responses
目录： 技术文章
How Does Collagen Tripeptide Act on the Skin: Stratum Corneum Delivery, Matrix Protection, and Regulation of Collagen Homeostasis
目录： 技术文章
What Determines Collagen Function: From Triple-Helix Formation to Hierarchical Assembly, Crosslink Maturation, and Dynamic Remodeling
目录： 技术文章
Mechanisms of Retinol Action in the Skin: From Metabolic Activation and RAR/RXR-Mediated Transcriptional Regulation to Epidermal Renewal and Collagen Homeostasis
目录： 技术文章
Mechanisms by Which PDRN Participates in Skin Repair: A2A Receptor-Related Signaling, Nucleotide Salvage, and Extracellular Matrix Remodeling
目录： 技术文章
What Is “Plant Collagen”? Distinguishing Ingredient Types, Structural Differences, Production Methods, and Skincare Effects
目录： 技术文章
How Coenzyme Q10 Acts on the Skin: Mitochondrial Electron Transfer, Antioxidant Protection of Membrane Lipids, and Lipid-Carrier Delivery
目录： 技术文章
The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis
目录： 技术文章
Mechanistic Basis of Acetyl Hexapeptide-8 in the Management of Expression Lines: SNARE Complex Interference, Constraints on Percutaneous Delivery, and Combination Strategies
目录： 技术文章
Structural Characteristics of Ergothioneine, OCTN1-Mediated Uptake by Skin Cells, and Antioxidant Mechanisms
目录： 技术文章
Differences Between Animal-Derived Collagen and Recombinant Collagen in Skincare: Sequence and Structure, Safety, Skin Effects, and Evidence Evaluation
目录： 技术文章
5mC DNA甲基化的调控机制
目录： 技术文章
此产品的引用文献
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
Copyright © 2023至今 上海阿拉丁生化科技股份有限公司 保留所有权利。
危险品化学品经营许可证（带存储）