十二烷基硫酸钠

规格或纯度: Reagent Plus，≥98.5%（GC）

CAS编号: 151-21-3
分子式: CH₃(CH₂)₁₁OSO₃Na
分子量: 288.38
EC号: 205-788-1
PubChem编号: 3423265

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货号 (SKU)	包装规格	是否现货
S432155-10g	10g	现货
S432155-25g	25g	现货
S432155-100g	100g	现货
S432155-250g	250g	现货
S432155-500g	500g	期货
S432155-1kg	1kg	期货

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基本描述

别名	月桂基硫酸盐钠盐, Dodecyl sulfate 钠盐, Sodium lauryl sulfate, SDS, Dodecyl sodium sulfate
英文别名	Sodium dodecyl sulfate\|151-21-3\|SODIUM LAURYL SULFATE\|Sodium dodecylsulfate\|Sodium lauryl sulphate\|Sodium dodecyl sulphate\|Neutrazyme\|Sodium n-dodecyl sulfate\|Irium\|Sulfuric acid monododecyl ester sodium salt\|Dodecyl sulfate sodium salt\|Dodecyl sodium sul
规格或纯度	Reagent Plus，≥98.5%（GC）
英文名称	Sodium dodecyl sulfate
生化机理	十二烷基硫酸钠（SDS）是一种阴离子去污剂，可通过疏水相互作用与蛋白质形成复合物。已有研究报道称蛋白质-SDS复合物的流体动力学功能受其多肽链长度的控制。因此，基于SDS的电泳技术可根据蛋白质的分子量而将蛋白质分子进行分离。此外，SDS还可溶解细胞膜并提取膜结合蛋白。
产品介绍	十二烷基硫酸钠(SDS)是一种阴离子表面活性剂，又称月桂基硫酸盐。应用十二烷基硫酸钠（SDS）已用于：基于选择性化合物的敏感性进行的肠杆菌科菌株鉴定对人体皮肤的体外和体内处理，以评估27-kDa热激蛋白(HSP27)在潜在皮肤刺激方面的核定位作用猪心脏瓣膜组织脱细胞处理精子以体外诱导精子解聚阴离子洗涤剂十二烷基硫酸钠被用作一种检测化合物，用于研究解淀粉芽孢杆菌KPS46是否能在大豆（Glycine max L.）中诱导针对几种疾病的引发、信号传导、蛋白质产生以及系统保护。 Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is a versatile anionic surfactant with a broad range of applications in cell biology, biochemistry, and various industries. Its amphiphilic nature, characterized by a hydrophobic hydrocarbon tail and a hydrophilic sulfate head group, makes it an effective detergent capable of solubilizing and denaturing proteins, lipids, and other hydrophobic molecules. In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity. Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.

名称和标识符

EC号	205-788-1
IUPAC Name	sodium;dodecyl sulfate
INCHI	InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChi Key	DBMJMQXJHONAFJ-UHFFFAOYSA-M
Canonical SMILES	CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]
Isomeric SMILES	CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]
PubChem CID	3423265
分子量	288.38

化学和物理性质

溶解性	水溶性
敏感性	吸湿的
熔点	204-207°C

安全和危险性（GHS）

象形图	Corrosive Harmful Flammable
信号词	Danger
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H373: Causes damage to organs through prolonged or repeated exposure H401: Toxic to aquatic life
预防措施声明	P261,P305+P351+P338,P273,P280,P370+P378,P310,P302+P352,P405,P501,P312,P264,P271,P270,P304+P340,P337+P313,P403+P233,P332+P313,P391,P330,P301+P312
Class	4.1
Merck Index	8636

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参考文献

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十二烷基硫酸钠

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基本描述

名称和标识符

化学和物理性质

安全和危险性（GHS）

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