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乙腈

规格或纯度: 色谱级,≥99.9%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
A104440-500ml
500ml 现货 Stock Image
A104440-1L
1L 期货 Stock Image
A104440-4L
4L 现货 Stock Image
A104440-4×4L
4×4L 期货 Stock Image
A104440-12×500ml
12×500ml 现货 Stock Image

基本描述

别名 色谱乙腈 | 甲基氰 | 氰甲烷 | 乙腈
英文别名 ACN | Acetonitril (GERMAN, DUTCH) | ACETONITRILE | ace-tonitrile | aceto-nitrile | acetonitrile- | DTXCID909 | acetonitnle | Acetonitrile 1000 microg/mL in Methanol | Acetonitrile, puriss., 95% | Acetonitrile, Environmental Grade | Acetonitrile, for DNA s
规格或纯度 色谱级,≥99.9%
英文名称 Acetonitrile
应用 乙腈最主要的用途是作溶剂。在石油工业中用于从石油烃中除去焦油、酚等物质的溶剂。在油脂工业中用作从动植物油中抽提脂肪酸的溶剂,在医药上用于甾族类药物的再结晶的反应介质。乙腈是医药(维生素B1),香料的中间体,是制造均三嗪氮肥增效剂的原料。也用作酒精的变性剂。此外,还可以用于合成乙胺、乙酸等,并在织物染色、照明工业中也有许多用途。
运输条件 常规运输
产品介绍

有轻微醚气味。有毒。燃烧时发光火焰。能与水、乙醚、甲醇、丙酮、氯仿、四氯化碳、氯化乙烯、乙酸甲酯、乙酸乙酯、乙酰胺溶液和许多不饱和烃混溶,不能与饱和烃混溶。能溶解一些无机盐类,如硝酸银、硝酸锂和溴化镁等。能与水形成共沸混合物(含水16%) 乙腈最主要的用途是作溶剂。在石油工业中用于从石油烃中除去焦油、酚等物质的溶剂。在油脂工业中用作从动植物油中抽提脂肪酸的溶剂,在医药上用于甾族类药物的再结晶的反应介质。乙腈是医药(维生素B1),香料的中间体,是制造均三嗪氮肥增效剂的原料。也用作酒精的变性剂。此外,还可以用于合成乙胺、乙酸等,并在织物染色、照明工业中也有许多用途。


名称和标识符

EC号 200-835-2
IUPAC Name acetonitrile
INCHI InChI=1S/C2H3N/c1-2-3/h1H3
InChi Key WEVYAHXRMPXWCK-UHFFFAOYSA-N
Canonical SMILES CC#N
Isomeric SMILES CC#N
WGK Germany 2
PubChem CID 6342
UN Number 1648
Packing Group II
分子量 41.05
Beilstein号 741857

化学和物理性质

溶解性 Miscible with water, alcohols, ethers, acetone, chloroform, carbon tetrachloride and ethylene chloride. Immiscible with saturated hydrocarbons (petroleum fractions).
密度 0.786
折光率 1.343-1.345
闪点(℃) 2 °C
沸点 81-82°C
熔点 -46°C

安全和危险性(GHS)

一般危化品 一般危化品
象形图
ghs07

Harmful

ghs02

Flammable

信号词 Danger
危险声明 H319: Causes serious eye irritation
H302: Harmful if swallowed
H225: Highly Flammable liquid and vapor
H312: Harmful in contact with skin
H332: Harmful if inhaled
预防措施声明 P261,P305+P351+P338,P280,P370+P378,P210,P302+P352,P321,P501,P233,P240,P264,P403+P235,P303+P361+P353,P271,P241,P270,P304+P340,P362+P364,P330,P242,P243,P264+P265,P301+P317,P317,P337+P317
WGK Germany 2
Class 3
Merck Index 70

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FAQ
N-溴代糖精

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产品问答

登录提交问题 Hover me 请先登录再提交问题
这个可以直接用于高效液相色谱的流动相而不过滤么么
问题由 陈晓 于 2023年9月17日 19:04 创建

您好,可以的直接做流动相,但是过滤下更好。

如何储存
问题由 罗 静茹 于 2022年7月4日 19:03 创建

常温储存即可,需阴凉干燥的环境

参考文献

1. Amrit Poudel,Se-Gun Kim,Ramakanta Lamichhane,Yun-Kyung Kim,Hyung-Kwon Jo,Hyun-Ju Jung.  (2013-02-14)  Quantitative assessment of traditional Oriental herbal formulation Samhwangsasim-tang using UPLC technique..  Journal of chromatographic science,  52  ((2)):  (176-185).  [PMID:23403059]
2. J J Baeza-Baeza,C Ortiz-Bolsico,J R Torres-Lapasió,M C García-Álvarez-Coque.  (2013-03-05)  Approaches to model the retention and peak profile in linear gradient reversed-phase liquid chromatography..  Journal of chromatography. A,  1284  ():  (28-35).  [PMID:23453677]
3. Urs C Meier.  (2013-03-23)  Detection and identification of hydrolysis products of sulfur mustards at trace levels in environmental samples using liquid chromatography solid phase extraction combined with off-line nuclear magnetic resonance analysis..  Journal of chromatography. A,  1286  ():  (159-165).  [PMID:23518263]
4. Ramalingam Peraman,Sasikala Mallikarjuna,Pravalika Ammineni,Vinod kumar Kondreddy.  (2013-10-25)  RP-HPLC method development and validation for simultaneous estimation of atorvastatin calcium and pioglitazone hydrochloride in pharmaceutical dosage form..  Journal of chromatographic science,  52  ((9)):  (1038-1042).  [PMID:24152592]
5. Tao Li,Ya-Jun Shu,Jia-Yin Cheng,Run-Cheng Liang,Shao-Na Dian,Xiao-Xun Lv,Meng-Qi Yang,Shu-Ling Huang,Gang Chen,Fan Yang.  (2013-11-19)  Pharmacokinetics and efficiency of brain targeting of ginsenosides Rg1 and Rb1 given as Nao-Qing microemulsion..  Drug development and industrial pharmacy,  41  ((2)):  (224-231).  [PMID:24237326]
6. Gang Ahn,Dong Min Park,Jun Won Park,Hyo-Young Kim,Joo-Youn Cho,Su-jin Rhee,In-Jin Jang,Hark Kyun Kim.  (2014-01-25)  A rapid, simple and reliable HPLC-triple quadrupole tandem mass spectrometer method for a simultaneous quantification of irinotecan and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN38) in mouse plasma..  Biomedical chromatography : BMC,  28  ((7)):  (919-922).  [PMID:24458571]
7. Mohd Aftab Alam,Fahad I Al-Jenoobi,Abdullah M Al-Mohizea.  (2014-03-29)  High-throughput ultra-performance LC-MS-MS method for analysis of diclofenac sodium in rabbit plasma..  Journal of chromatographic science,  53  ((1)):  (47-53).  [PMID:24668042]
8. Lina Raudone,Ramune Bobinaite,Valdimaras Janulis,Pranas Viskelis,Sonata Trumbeckaite.  (2014-04-05)  Effects of raspberry fruit extracts and ellagic acid on respiratory burst in murine macrophages..  Food & function,  ((6)):  (1167-1174).  [PMID:24699912]
9. Xiaoping Li,Bixia Xuan,Qingyao Shou,Zhengwu Shen.  (2014-04-09)  New flavonoids from Campylotropis hirtella with immunosuppressive activity..  Fitoterapia,  95  ():  (220-228).  [PMID:24709073]
10. Yujuan Wang,Mones S Abu-Asab,Cheng-Rong Yu,Zhongshu Tang,Defen Shen,Jingsheng Tuo,Xuri Li,Chi-Chao Chan.  (2014-04-09)  Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration..  Laboratory investigation; a journal of technical methods and pathology,  94  ((6)):  (674-682).  [PMID:24709779]
11. Li Ren,Zheng Wang,Yiceng Lou,Lu Zheng,Heng Zheng,Chunping Yin.  (2014-04-22)  Determination of bevantolol in human plasma using liquid chromatography-electrospray ionization tandem mass spectrometry and its application to a bioequivalence study..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  959  ():  (16-21).  [PMID:24747519]
12. Shucai Li,Wenwen Wang,Huan Tang,Kai Chen,Jianhong Yang,Linhong He,Haoyu Ye,Aihua Peng,Lijuan Chen.  (2014-04-29)  Comparison of counter-current chromatography and preparative high performance liquid chromatography applied to separating minor impurities in drug preparations..  Journal of chromatography. A,  1344  ():  (51-58).  [PMID:24767948]
13. Masafumi Sakono,Akira Seko,Yoichi Takeda,Jun-ichi Aikawa,Masakazu Hachisu,Akihiko Koizumi,Kohki Fujikawa,Yukishige Ito.  (2014-04-29)  Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions..  Biochimica et biophysica acta,  1840  ((9)):  (2904-2913).  [PMID:24769397]
14. Tingting Wang,Ying Feng,Xiaohan Jin,Xuxin Fan,Jacques Crommen,Zhengjin Jiang.  (2014-05-13)  Liposome electrokinetic chromatography based in vitro model for early screening of the drug-induced phospholipidosis risk..  Journal of pharmaceutical and biomedical analysis,  96  ():  (263-271).  [PMID:24814828]
15. Wenchu Yang,Robert Kernstock,Neal Simmons,Ala Alak.  (2014-05-28)  Guanidinated protein internal standard for immunoaffinity-liquid chromatography/tandem mass spectrometry quantitation of protein therapeutics..  Rapid communications in mass spectrometry : RCM,  28  ((13)):  (1489-1500).  [PMID:24861599]
16. Diarmaid J Murphy,Delphine Desjardins,Nathalie Dereuddre-Bosquet,Patricia Brochard,Ludivine Perrot,Alain Pruvost,Roger Le Grand,Ole Lagatie,Leen Vanhooren,Maxim Feyaerts,Jens van Roey,R Karl Malcolm.  (2014-05-28)  Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir..  The Journal of antimicrobial chemotherapy,  69  ((9)):  (2477-2488).  [PMID:24862093]
17. Zhitao Liang,Kayan Oh,Yuqing Wang,Tao Yi,Hubiao Chen,Zhongzhen Zhao.  (2014-05-28)  Cell type-specific qualitative and quantitative analysis of saikosaponins in three Bupleurum species using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry..  Journal of pharmaceutical and biomedical analysis,  97  ():  (157-165).  [PMID:24863374]
18. Élida Alechaga,Encarnación Moyano,M Teresa Galceran.  (2014-06-03)  Mixed-mode liquid chromatography coupled to tandem mass spectrometry for the analysis of aminoglycosides in meat..  Analytical and bioanalytical chemistry,  406  ((20)):  (4941-4953).  [PMID:24881895]
19. Yuangang Zu,Weiwei Wu,Xiuhua Zhao,Yong Li,Weiguo Wang,Chen Zhong,Yin Zhang,Xue Zhao.  (2014-06-03)  Enhancement of solubility, antioxidant ability and bioavailability of taxifolin nanoparticles by liquid antisolvent precipitation technique..  International journal of pharmaceutics,  471  ((1-2)):  (366-376).  [PMID:24882039]
20. Zhi-Yuan Wu,Na Liu,Bingjie Qin,Li Huang,Fei Yu,Keduo Qian,Susan L Morris-Natschke,Shibo Jiang,Chin Ho Chen,Kuo-Hsiung Lee,Lan Xie.  (2014-06-05)  Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS..  ChemMedChem,  ((7)):  (1546-1555).  [PMID:24895029]
21. Amadeu Gavaldà,Israel Ramos,Carla Carcasona,Elena Calama,Raquel Otal,José Luis Montero,Sonia Sentellas,Monica Aparici,Dolors Vilella,Joan Alberti,Jorge Beleta,Montserrat Miralpeix.  (2014-06-15)  The in\xa0vitro and in\xa0vivo profile of aclidinium bromide in comparison with glycopyrronium bromide..  Pulmonary pharmacology & therapeutics,  28  ((2)):  (114-121).  [PMID:24928173]
22. Meriyem Aktas, Stefan Köster, Sarah Kizilirmak, Javier C Casanova, Heidi Betz, Christiane Fritz, Roman Moser, Özkan Yildiz, Franz Narberhaus,.  (2014-06-17)  Enzymatic properties and substrate specificity of a bacterial phosphatidylcholine synthase..  The FEBS journal,  281  ((15)):  ( 3523-3541 ).  [PMID:24931117]
23. Da-Hye Kim,Mi-Young Lee,Jeong-Eun Oh.  (2014-06-24)  Perfluorinated compounds in serum and urine samples from children aged 5-13 years in South Korea..  Environmental pollution (Barking, Essex : 1987),  192  ():  (171-178).  [PMID:24952613]
24. Byung Joo Kim,Hyungwoo Kim,Guem San Lee,Insuk So,Seon Jeong Kim.  (2014-06-24)  Effects of San-Huang-Xie-Xin-tang, a traditional Chinese prescription for clearing away heat and toxin, on the pacemaker activities of interstitial cells of Cajal from the murine small intestine..  Journal of ethnopharmacology,  155  ((1)):  (744-752).  [PMID:24953035]
25. Eva Gorrochategui,Josefina Casas,Elisabet Pérez-Albaladejo,Olga Jáuregui,Cinta Porte,Sílvia Lacorte.  (2014-06-28)  Characterization of complex lipid mixtures in contaminant exposed JEG-3 cells using liquid chromatography and high-resolution mass spectrometry..  Environmental science and pollution research international,  21  ((20)):  (11907-11916).  [PMID:24969426]
26. Keyu Zhang,Sumei Li,Wenli Zheng,Lifang Zhang,Chunmei Wang,Xiaoyang Wang,Chenzhong Fei,Feiqun Xue,Mi Wang.  (2014-07-01)  Identification of in vitro metabolites of a new anticoccidial drug nitromezuril using HepG2 cells, rat S9 and primary hepatocytes by liquid chromatography/tandem mass spectrometry..  Rapid communications in mass spectrometry : RCM,  28  ((15)):  (1723-1734).  [PMID:24975253]
27. Paulami Pal,R S Thakur,Subhabrata Ray,Bhaskar Mazumder.  (2014-07-02)  Design and development of a safer non-invasive transungual drug delivery system for topical treatment of onychomycosis..  Drug development and industrial pharmacy,  41  ((7)):  (1095-1099).  [PMID:24980914]
28. Neda Ahmadiani,Rebecca J Robbins,Thomas M Collins,M Monica Giusti.  (2014-07-06)  Anthocyanins contents, profiles, and color characteristics of red cabbage extracts from different cultivars and maturity stages..  Journal of agricultural and food chemistry,  62  ((30)):  (7524-7531).  [PMID:24991694]
29. Mingming Yu,Hazem E Hassan,Ahmed Ibrahim,Kenneth S Bauer,Deanna L Kelly,Jia Bei Wang.  (2014-07-06)  Simultaneous determination of L-tetrahydropalmatine and cocaine in human plasma by simple UPLC-FLD method: application in clinical studies..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  965  ():  (39-44).  [PMID:24996068]
30. Takashi Osawa,Takafumi Naito,Takanori Kaneko,Yasuaki Mino,Kazunori Ohnishi,Hiroshi Yamada,Junichi Kawakami.  (2014-07-11)  Blood distribution of bortezomib and its kinetics in multiple myeloma patients..  Clinical biochemistry,  47  ((15)):  (54-59).  [PMID:25011071]
31. Le Ngoc Tran,Shuchi Dixit,Jung Hag Park.  (2014-07-20)  Enantioseparation of basic chiral compounds on a clindamycin phosphate-silica/zirconia hybrid monolith by capillary electrochromatography..  Journal of chromatography. A,  1356  ():  (289-293).  [PMID:25037777]
32. Shasha Li,Xingang Liu,Yulong Zhu,Fengshou Dong,Jun Xu,Minmin Li,Yongquan Zheng.  (2014-07-21)  A statistical approach to determine fluxapyroxad and its three metabolites in soils, sediment and sludge based on a combination of chemometric tools and a modified quick, easy, cheap, effective, rugged and safe method..  Journal of chromatography. A,  1358  ():  (46-51).  [PMID:25039069]
33. Yoshiki Asakawa,Eiichi Yamamoto,Naoki Asakawa.  (2014-07-22)  Selective retention of basic compounds by metal aquo-ion affinity chromatography..  Journal of separation science,  37  ((19)):  (2641-2651).  [PMID:25044622]
34. Christoph Bueschl,Bernhard Kluger,Marc Lemmens,Gerhard Adam,Gerlinde Wiesenberger,Valentina Maschietto,Adriano Marocco,Joseph Strauss,Stephan Bödi,Gerhard G Thallinger,Rudolf Krska,Rainer Schuhmacher.  (2014-07-25)  A novel stable isotope labelling assisted workflow for improved untargeted LC-HRMS based metabolomics research..  Metabolomics : Official journal of the Metabolomic Society,  10  ((4)):  (754-769).  [PMID:25057268]
35. Bart Hens,Joachim Brouwers,Bart Anneveld,Maura Corsetti,Mira Symillides,Maria Vertzoni,Christos Reppas,David B Turner,Patrick Augustijns.  (2014-07-30)  Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools..  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,  63  ():  (233-242).  [PMID:25064697]
36. Susan M Christner,Robert A Parise,Erica D Levine,Naiyer A Rizvi,Mrinal M Gounder,Jan H Beumer.  (2014-08-30)  Quantitative method for the determination of iso-fludelone (KOS-1803) in human plasma by LC-MS/MS..  Journal of pharmaceutical and biomedical analysis,  100  ():  (199-204).  [PMID:25168219]
37. Atsuki Matsubara,Yoshihiro Izumi,Shin Nishiumi,Makoto Suzuki,Takeshi Azuma,Eiichiro Fukusaki,Takeshi Bamba,Masaru Yoshida.  (2014-09-03)  Supercritical fluid extraction as a preparation method for mass spectrometry of dried blood spots..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  969  ():  (199-204).  [PMID:25178194]
38. Dennis Åsberg,Marek Leśko,Jörgen Samuelsson,Krzysztof Kaczmarski,Torgny Fornstedt.  (2014-09-06)  Method transfer from high-pressure liquid chromatography to ultra-high-pressure liquid chromatography. I. A thermodynamic perspective..  Journal of chromatography. A,  1362  ():  (206-217).  [PMID:25189333]
39. Gulcin Tezcan,Berrin Tunca,Ahmet Bekar,Murat Yalcin,Saliha Sahin,Ferah Budak,Gulsah Cecener,Unal Egeli,Cevdet Demir,Gokcen Guvenc,Gozde Yilmaz,Leman Gizem Erkan,Hulusi Malyer,Mevlut Ozgur Taskapilioglu,Turkkan Evrensel,Ayhan Bilir.  (2014-09-13)  Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines..  Cellular and molecular neurobiology,  35  ((2)):  (175-187).  [PMID:25212824]
40. Thomas G Rosano,Seo Na,Kenneth Ihenetu,Thomas A Swift,Michelle Wood.  (2014-09-14)  Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology..  Journal of analytical toxicology,  38  ((8)):  (495-506).  [PMID:25217537]
41. B S Lopez,S Giguère,L J Berghaus,M A Mullins,J L Davis.  (2014-09-17)  Pharmacokinetics of danofloxacin and N-desmethyldanofloxacin in adult horses and their concentration in synovial fluid..  Journal of veterinary pharmacology and therapeutics,  38  ((2)):  (123-129).  [PMID:25224604]
42. Weifeng Yao,Haiwei Gu,Jiangjiang Zhu,Gregory Barding,Haibo Cheng,Beihua Bao,Li Zhang,Anwei Ding,Wei Li.  (2014-09-24)  Integrated plasma and urine metabolomics coupled with HPLC/QTOF-MS and chemometric analysis on potential biomarkers in liver injury and hepatoprotective effects of Er-Zhi-Wan..  Analytical and bioanalytical chemistry,  406  ((28)):  (7367-7378).  [PMID:25245419]
43. Edyta Szałek,Agnieszka Karbownik,Katarzyna Sobańska,Włodzimierz Płotek,Tomasz Grabowski,Małgorzata Nowak,Edmund Grześkowiak.  (2014-10-03)  The penetration of sunitinib through the blood-brain barrier after the administration of ciprofloxacin..  Acta poloniae pharmaceutica,  71  ((4)):  (691-697).  [PMID:25272897]
44. Panteleimon J Marsouvanidis,Marleen Melis,Erik de Blois,Wout A P Breeman,Eric P Krenning,Theodosia Maina,Berthold A Nock,Marion de Jong.  (2014-10-07)  In vivo enzyme inhibition improves the targeting of [177Lu]DOTA-GRP(13-27) in GRPR-positive tumors in mice..  Cancer biotherapy & radiopharmaceuticals,  29  ((9)):  (359-367).  [PMID:25286347]
45. Jun Ueyama,Isao Saito,Ayuko Takaishi,Hiroshi Nomura,Mai Inoue,Aya Osaka,Yuka Sugiura,Yumi Hayashi,Shinya Wakusawa,Hiroko Ogi,Kimio Inuzuka,Michihiro Kamijima,Takaaki Kondo.  (2014-10-09)  A revised method for determination of dialkylphosphate levels in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: application to human urine samples from Japanese children..  Environmental health and preventive medicine,  19  ((6)):  (405-413).  [PMID:25293697]
46. Pei Wang,Hui Zhang,Hailong Yang,Lei Nie,Hengchang Zang.  (2014-10-14)  Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  137  ():  (1403-1408).  [PMID:25310261]
47. Clara Coscollà,Nuria León,Agustín Pastor,Vicent Yusà.  (2014-10-15)  Combined target and post-run target strategy for a comprehensive analysis of pesticides in ambient air using liquid chromatography-Orbitrap high resolution mass spectrometry..  Journal of chromatography. A,  1368  ():  (132-142).  [PMID:25311489]
48. Erik Helgeland,Lars Ertesvåg Breivik,Marc Vaudel,Øyvind Sverre Svendsen,Hilde Garberg,Jan Erik Nordrehaug,Frode Steingrimsen Berven,Anne Kristine Jonassen.  (2014-10-22)  Exploring the human plasma proteome for humoral mediators of remote ischemic preconditioning--a word of caution..  PloS one,  ((10)):  (e109279-e109279).  [PMID:25333471]
49. M A Morel,C Cagide,M A Minteguiaga,M S Dardanelli,S Castro-Sowinski.  (2014-10-30)  The Pattern of Secreted Molecules During the Co-Inoculation of Alfalfa Plants With Sinorhizobium meliloti and Delftia sp. strain JD2: An Interaction That Improves Plant Yield..  Molecular plant-microbe interactions : MPMI,  28  ((2)):  (134-142).  [PMID:25353366]
50. Mette Thing,Li Ågårdh,Susan Larsen,Rune Rasmussen,Jakob Pallesen,Nina Mertz,Jesper Kristensen,Martin Hansen,Jesper Østergaard,Claus Selch Larsen.  (2014-10-31)  A prodrug approach involving in situ depot formation to achieve localized and sustained action of diclofenac after joint injection..  Journal of pharmaceutical sciences,  103  ((12)):  (4021-4029).  [PMID:25354787]
51. Małgorzata Cebo,Martyna Kielmas,Justyna Adamczyk,Marek Cebrat,Zbigniew Szewczuk,Piotr Stefanowicz.  (2014-10-31)  Hydrogen-deuterium exchange in imidazole as a tool for studying histidine phosphorylation..  Analytical and bioanalytical chemistry,  406  ((30)):  (8013-8020).  [PMID:25354888]
52. Iwona Kowalska,Lukasz Pecio,Lukasz Ciesla,Wieslaw Oleszek,Anna Stochmal.  (2014-10-31)  Isolation, chemical characterization, and free radical scavenging activity of phenolics from Triticum aestivum L. aerial parts..  Journal of agricultural and food chemistry,  62  ((46)):  (11200-11208).  [PMID:25356666]
53. Sahng-Wook Hahm,Jieun Park,Se-Yeong Oh,Chul-Won Lee,Kun-Young Park,Hyunggee Kim,Yong-Suk Son.  (2014-11-08)  Anticancer properties of extracts from Opuntia humifusa against human cervical carcinoma cells..  Journal of medicinal food,  18  ((1)):  (31-44).  [PMID:25379883]
54. Daniel Zewge,Francis Gosselin,Denise M Kenski,Jenny Li,Vasant Jadhav,Yu Yuan,Sandhya S Nerurkar,David M Tellers,W Michael Flanagan,Ian W Davies.  (2014-11-15)  High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation..  Bioconjugate chemistry,  25  ((12)):  (2222-2232).  [PMID:25398098]
55. Thomas Bock,Wei-Hua Chen,Alessandro Ori,Nayab Malik,Noella Silva-Martin,Jaime Huerta-Cepas,Sean T Powell,Panagiotis L Kastritis,Georgy Smyshlyaev,Ivana Vonkova,Joanna Kirkpatrick,Tobias Doerks,Leo Nesme,Jochen Baßler,Martin Kos,Ed Hurt,Teresa Carlomagno,Anne-Claude Gavin,Orsolya Barabas,Christoph W Müller,Vera van Noort,Martin Beck,Peer Bork.  (2014-11-16)  An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum..  Nucleic acids research,  42  ((22)):  (13525-13533).  [PMID:25398899]
56. Martin Bachman,Santiago Uribe-Lewis,Xiaoping Yang,Michael Williams,Adele Murrell,Shankar Balasubramanian.  (2014-11-21)  5-Hydroxymethylcytosine is a predominantly stable DNA modification..  Nature chemistry,  ((12)):  (1049-1055).  [PMID:25411882]
57. Zhao-Yun Cao,Li-Hua Sun,Ren-Xiang Mou,Rong Zhou,Zhi-Wei Zhu,Ming-Xue Chen.  (2014-12-02)  A novel method for the simultaneous analysis of seven biothiols in rice (Oryza sativa L.) using hydrophilic interaction chromatography coupled with electrospray tandem mass spectrometry..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  976-977  ():  (19-26).  [PMID:25436484]
58. Meina Liu,Wen Cao,Yinghua Sun,Zhonggui He.  (2014-12-03)  Preparation, characterization and in vivo evaluation of formulation of repaglinide with hydroxypropyl-β-cyclodextrin..  International journal of pharmaceutics,  477  ((1-2)):  (159-166).  [PMID:25455768]
59. Haoyue Zhang,Tim Wood,Sarah P Young,David S Millington.  (2014-12-03)  A straightforward, quantitative ultra-performance liquid chromatography-tandem mass spectrometric method for heparan sulfate, dermatan sulfate and chondroitin sulfate in urine: an improved clinical screening test for the mucopolysaccharidoses..  Molecular genetics and metabolism,  114  ((2)):  (123-128).  [PMID:25458519]
60. Yonghong Liang,Shun Yao,Fang Liang,Jian Liang,Guangyu Huang,Min Liu,Huilian Huang.  (2014-12-03)  Structural characterization of steroidal saponins from Smilax trinervula using ultra high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  974  ():  (75-82).  [PMID:25463200]
61. Jiajia Yang,Yun Li,Jincheng Wang,Xiaoli Sun,Syed Mazhar Shah,Rong Cao,Jiping Chen.  (2014-12-04)  Novel sponge-like molecularly imprinted mesoporous silica material for selective isolation of bisphenol A and its analogues from sediment extracts..  Analytica chimica acta,  853  ():  (311-319).  [PMID:25467474]
62. Lee C Winchester,Anthony T Podany,Joshua S Baldwin,Brian L Robbins,Courtney V Fletcher.  (2014-12-08)  Determination of the rifamycin antibiotics rifabutin, rifampin, rifapentine and their major metabolites in human plasma via simultaneous extraction coupled with LC/MS/MS..  Journal of pharmaceutical and biomedical analysis,  104  ():  (55-61).  [PMID:25481085]
63. Joke Meeus,David J Scurr,Katie Amssoms,Koen Wuyts,Pieter Annaert,Martyn C Davies,Clive J Roberts,Guy Van den Mooter.  (2014-12-09)  In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor..  Journal of controlled release : official journal of the Controlled Release Society,  199  ():  (1-9).  [PMID:25485732]
64. Ying Zhou,Hongyun Wang,Ji Jiang,Pei Hu.  (2014-12-09)  Simultaneous determination of remimazolam and its carboxylic acid metabolite in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  976-977  ():  (78-83).  [PMID:25486614]
65. Yoshifumi Hagiya,Shotaro Kamata,Saya Mitsuoka,Norihiko Okada,Saori Yoshida,Junya Yamamoto,Rika Ohkubo,Yumi Abiko,Hidenori Yamada,Noriyuki Akahoshi,Tadashi Kasahara,Yoshito Kumagai,Isao Ishii.  (2014-12-17)  Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice..  Toxicology and applied pharmacology,  282  ((2)):  (195-206).  [PMID:25499718]
66. Anna Maria Sniecinska-Cooper,Ajit Jesang Shah,Dagmara Dimitriou,Ray Kruse Iles,Stephen Andrew Butler,Richard Bayford.  (2014-12-23)  Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  978-979  ():  (18-23).  [PMID:25531866]
67. Shu-Ping Zou,Miao Liu,Qiu-Liang Wang,Yan Xiong,Kun Niu,Yu-Guo Zheng,Yin-Chu Shen.  (2014-12-30)  Preparative separation of echinocandin B from Aspergillus nidulans broth using macroporous resin adsorption chromatography..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  978-979  ():  (111-117).  [PMID:25541471]
68. Fabrice Gritti,Alexandra Höltzel,Ulrich Tallarek,Georges Guiochon.  (2014-12-30)  The relative importance of the adsorption and partitioning mechanisms in hydrophilic interaction liquid chromatography..  Journal of chromatography. A,  1376  ():  (112-125).  [PMID:25542707]
69. Xingnan Li,Adrian A Franke.  (2014-12-30)  Improved profiling of estrogen metabolites by orbitrap LC/MS..  Steroids,  99  ((Pt A)):  (84-90).  [PMID:25543003]
70. Yuanyuan Li,Hengning Lian,Qingzhu Jia,Ying Wan.  (2015-01-03)  Proteome screening of pleural effusions identifies IL1A as a diagnostic biomarker for non-small cell lung cancer..  Biochemical and biophysical research communications,  457  ((2)):  (177-182).  [PMID:25554695]
71. Muneebah Adams,Carmen de Kock,Peter J Smith,Kirkwood M Land,Nicole Liu,Melissa Hopper,Allyson Hsiao,Andrew R Burgoyne,Tameryn Stringer,Mervin Meyer,Lubbe Wiesner,Kelly Chibale,Gregory S Smith.  (2015-01-07)  Improved antiparasitic activity by incorporation of organosilane entities into half-sandwich ruthenium(II) and rhodium(III) thiosemicarbazone complexes..  Dalton transactions (Cambridge, England : 2003),  44  ((5)):  (2456-2468).  [PMID:25559246]
72. Juanjuan Pi,Xia Wu,Shitian Yang,Pingyan Zeng,Yifan Feng.  (2015-01-08)  Rapid identification of erythrocyte phospholipids in Sprague-Dawley rats by ultra high performance liquid chromatography with electrospray ionization quadrupole time-of-flight tandem mass spectrometry..  Journal of separation science,  38  ((6)):  (886-893).  [PMID:25564825]
73. Xiuhong Wu,Shuhan Tang,Yan Jin,Yan Zhang,Masao Hattori,Xijun Wang,Hailong Zhang,Zhigang Wang.  (2015-01-23)  New analytical method for the study of metabolism of swertiamarin in rats after oral administration by UPLC-TOF-MS following DNPH derivatization..  Biomedical chromatography : BMC,  29  ((8)):  (1184-1189).  [PMID:25612327]
74. Eugenia Mato,Sílvia Barceló-Batllori,Irene Orera,Laia Selva,Martina Corra,Cintia González,Olga Bell,Enrique Lerma,Antonio Moral,José Ignacio Pérez,Alberto de Leiva.  (2015-01-27)  The proteomic 2D-DIGE approach reveals the protein voltage-dependent anion channel 2 as a potential therapeutic target in epithelial thyroid tumours..  Molecular and cellular endocrinology,  404  ():  (37-45).  [PMID:25617717]
75. Ali Athab Al-Kinani,Declan P Naughton,Gianpiero Calabrese,Anil Vangala,James R Smith,Barbara K Pierscionek,Raid G Alany.  (2015-02-11)  Analysis of 2-oxothiazolidine-4-carboxylic acid by hydrophilic interaction liquid chromatography: application for ocular delivery using chitosan nanoparticles..  Analytical and bioanalytical chemistry,  407  ((9)):  (2645-2650).  [PMID:25662935]
76. Shujiao Li,Hang Lin,Yuping Tang,Weixia Li,Juan Shen,Jun Kai,Shijun Yue,Guanxiong Shang,Zhenhua Zhu,Erxin Shang,Changbin Zhang,Li Zhang,Hui Yan,Pei Liu,Jin-ao Duan.  (2015-02-11)  Comparative metabolomics analysis on invigorating blood circulation for herb pair Gui-Hong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach..  Journal of pharmaceutical and biomedical analysis,  107  ():  (456-463).  [PMID:25668798]
77. K Dadakova,M Havelkova,B Kurkova,I Tlolkova,T Kasparovsky,Z Zdrahal,J Lochman.  (2015-02-18)  Proteome and transcript analysis of Vitis vinifera cell cultures subjected to Botrytis cinerea infection..  Journal of proteomics,  119  ():  (143-153).  [PMID:25688916]
78. Huihui Ti,Ruifen Zhang,Mingwei Zhang,Zhencheng Wei,Jianwei Chi,Yuanyuan Deng,Yan Zhang.  (2015-02-24)  Effect of extrusion on phytochemical profiles in milled fractions of black rice..  Food chemistry,  178  ():  (186-194).  [PMID:25704700]
79. Jing Zhou,Man Zhou,Fei-Fei Yang,Chun-Yu Liu,Rui-Le Pan,Qi Chang,Xin-Min Liu,Yong-Hong Liao.  (2015-02-28)  Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions..  Molecular pharmaceutics,  12  ((4)):  (1084-1095).  [PMID:25723098]
80. Yogesh T Patel,Megan O Jacus,Nidal Boulos,Jason D Dapper,Abigail D Davis,Pradeep K Vuppala,Burgess B Freeman,Kumarasamypet M Mohankumar,Stacy L Throm,Richard J Gilbertson,Clinton F Stewart.  (2015-03-01)  Preclinical examination of clofarabine in pediatric ependymoma: intratumoral concentrations insufficient to warrant further study..  Cancer chemotherapy and pharmacology,  75  ((5)):  (897-906).  [PMID:25724157]
81. James Hemphill,Qingyang Liu,Rajendra Uprety,Subhas Samanta,Michael Tsang,Rudolph L Juliano,Alexander Deiters.  (2015-03-04)  Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides..  Journal of the American Chemical Society,  137  ((10)):  (3656-3662).  [PMID:25734836]
82. Aliya Ahmad,Kalavathy Ramasamy,Abu Bakar Abdul Majeed,Vasudevan Mani.  (2015-03-11)  Enhancement of β-secretase inhibition and antioxidant activities of tempeh, a fermented soybean cake through enrichment of bioactive aglycones..  Pharmaceutical biology,  53  ((5)):  (758-766).  [PMID:25756802]
83. Laura E Herring,Kyle G Grant,Kevin Blackburn,Jason M Haugh,Michael B Goshe.  (2015-03-18)  Development of a tandem affinity phosphoproteomic method with motif selectivity and its application in analysis of signal transduction networks..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  988  ():  (166-174).  [PMID:25777480]
84. Fang Bo,Ting Dou,Xingrui Wang,Paul Owusu Donkor,Huizi Ouyang,Yanxu Chang,Yaru Tu,Xiumei Gao,Jun He.  (2015-04-13)  A validated LC-MS/MS method for determination of periplogenin in rat plasma and its application in pharmacokinetic study..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  990  ():  (80-83).  [PMID:25864008]
85. Cong Zha,Xue Hua Jiang,Shi Fang Peng.  (2015-04-16)  iTRAQ-based quantitative proteomic analysis on S100 calcium binding protein A2 in metastasis of laryngeal cancer..  PloS one,  10  ((4)):  (e0122322-e0122322).  [PMID:25874882]
86. Benetode Konziase.  (2015-04-29)  Biotinylated probes of artemisinin with labeling affinity toward Trypanosoma brucei brucei target proteins..  Analytical biochemistry,  482  ():  (25-31).  [PMID:25912417]
87. Jiali Liu,Yuan Fang,Lan Yang,Xuemei Qin,Guanhua Du,Xiaoxia Gao.  (2015-04-29)  A qualitative, and quantitative determination and pharmacokinetic study of four polyacetylenes from Radix Bupleuri by UPLC-PDA-MS..  Journal of pharmaceutical and biomedical analysis,  111  ():  (257-265).  [PMID:25912847]
88. Qinggang Wang,Brian Lingfeng He,Jin Zhang,Yande Huang,Brent Kleintop,Thomas Raglione.  (2015-04-29)  Transition metal-induced degradation of a pharmaceutical compound in reversed-phase liquid chromatographic analysis..  Journal of pharmaceutical and biomedical analysis,  111  ():  (288-296).  [PMID:25916912]
89. Ute Linz,Michelle Hupert,Beatrix Santiago-Schübel,Sascha Wien,Julia Stab,Sylvia Wagner.  (2015-04-29)  Transport of treosulfan and temozolomide across an in-vitro blood-brain barrier model..  Anti-cancer drugs,  26  ((7)):  (728-736).  [PMID:25919318]
90. Michael W Hornung,Patricia A Kosian,Jonathan T Haselman,Joseph J Korte,Katie Challis,Chitralekha Macherla,Erica Nevalainen,Sigmund J Degitz.  (2015-05-09)  In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles..  Toxicological sciences : an official journal of the Society of Toxicology,  146  ((2)):  (254-264).  [PMID:25953703]
91. Moran Zur,Noa Cohen,Riad Agbaria,Arik Dahan.  (2015-05-11)  The biopharmaceutics of successful controlled release drug product: Segmental-dependent permeability of glipizide vs. metoprolol throughout the intestinal tract..  International journal of pharmaceutics,  489  ((1-2)):  (304-310).  [PMID:25957705]
92. Maryam Lashgari,Chanbasha Basheer,Hian Kee Lee.  (2015-05-13)  Application of surfactant-templated ordered mesoporous material as sorbent in micro-solid phase extraction followed by liquid chromatography-triple quadrupole mass spectrometry for determination of perfluorinated carboxylic acids in aqueous media..  Talanta,  141  ():  (200-206).  [PMID:25966403]
93. H Li,S Cui,S Wang,X Jiang,S Zhang,R Zhang,P P Fu,X Sun.  (2015-05-15)  Ultrasensitive UPLC-MS/MS method for analysis of etheno-DNA adducts in human white blood cells..  Free radical research,  49  ((9)):  (1049-1054).  [PMID:25968941]
94. Prashant Kumar Singh,Alok Kumar Shrivastava,Antra Chatterjee,Sarita Pandey,Snigdha Rai,Shilpi Singh,L C Rai.  (2015-05-30)  Cadmium toxicity in diazotrophic Anabaena spp. adjudged by hasty up-accumulation of transporter and signaling and severe down-accumulation of nitrogen metabolism proteins..  Journal of proteomics,  127  ((Pt A)):  (134-146).  [PMID:26021478]
95. Brian T Nasipak,Teresita Padilla-Benavides,Karin M Green,John D Leszyk,Wenjie Mao,Silvana Konda,Saïd Sif,Scott A Shaffer,Yasuyuki Ohkawa,Anthony N Imbalzano.  (2015-06-18)  Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme..  Nature communications,  ():  (7441-7441).  [PMID:26081415]
96. Daisuke Fujinami,James Nyirenda,Shunsuke Matsumoto,Daisuke Kohda.  (2015-06-22)  Structural elucidation of an asparagine-linked oligosaccharide from the hyperthermophilic archaeon, Archaeoglobus fulgidus..  Carbohydrate research,  413  ():  (55-62).  [PMID:26093517]
97. Grant A Abernethy.  (2015-07-04)  Generation of semicarbazide from natural azine development in foods, followed by reaction with urea compounds..  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment,  32  ((9)):  (1416-1430).  [PMID:26140456]
98. Żaneta Rembisz,Dorota Bzdurska,Justyna Obiedzińska,Ramón Martínez-Máńez,Robert Zakrzewski.  (2015-07-15)  A derivatization approach using pyrylium salts for the sensitive and simple determination of sulfide in spring water by high performance liquid chromatography..  Journal of chromatography. A,  1407  ():  (184-192).  [PMID:26163932]
99. Vincenzo Cunsolo,Elisa Fasoli,Rosaria Saletti,Vera Muccilli,Serafina Gallina,Pier Giorgio Righetti,Salvatore Foti.  (2015-07-21)  Zeus, Aesculapius, Amalthea and the proteome of goat milk..  Journal of proteomics,  128  ():  (69-82).  [PMID:26193489]
100. Xi-Wen Tong,Bing Chen,Li-Hua Huang,Qi-Li Feng,Le Kang.  (2015-07-28)  Proteomic analysis reveals that COP9 signalosome complex subunit 7A (CSN7A) is essential for the phase transition of migratory locust..  Scientific reports,  ():  (12542-12542).  [PMID:26212173]
101. .  ()  Long-circulating self-assembled cholesteryl albumin nanoparticles enhance tumor accumulation of hydrophobic anticancer drug..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e,    ():  ().  [PMID:26212785]
102. Lisette Wirsing,Frank Klawonn,Wiebke Anna Sassen,Heinrich Lünsdorf,Corinna Probst,Michael Hust,Ralf R Mendel,Tobias Kruse,Lothar Jänsch.  (2015-07-29)  Linear Discriminant Analysis Identifies Mitochondrially Localized Proteins in Neurospora crassa..  Journal of proteome research,  14  ((9)):  (3900-3911).  [PMID:26215788]
103. Rodney A Velliquette,Kerry Grann,Stephen R Missler,Jennifer Patterson,Chun Hu,Kevin W Gellenbeck,Jeffrey D Scholten,R Keith Randolph.  (2015-08-08)  Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial..  Nutrition & metabolism,  12  ():  (27-27).  [PMID:26246845]
104. Hongxin Cao,Aihua Zhang,Hui Sun,Xiaohang Zhou,Yu Guan,Qi Liu,Ling Kong,Xijun Wang.  (2015-08-11)  Metabolomics-proteomics profiles delineate metabolic changes in kidney fibrosis disease..  Proteomics,  15  ((21)):  (3699-3710).  [PMID:26256572]
105. Chien-Ming Chen,Shih-Ming Chen,Po-Jen Chien,Han-Yin Yu.  (2015-08-13)  Development of an enzymatic assay system of D-lactate using D-lactate dehydrogenase and a UV-LED fluorescent spectrometer..  Journal of pharmaceutical and biomedical analysis,  116  ():  (150-155).  [PMID:26265307]
106. Valérie Gagnaire,Julien Jardin,Houem Rabah,Valérie Briard-Bion,Gwénaël Jan.  (2015-08-15)  Emmental Cheese Environment Enhances Propionibacterium freudenreichii Stress Tolerance..  PloS one,  10  ((8)):  (e0135780-e0135780).  [PMID:26275229]
107. Mohanareddy Chilukuri,Katreddi Hussainreddy,Papadasu Narayanareddy,Madireddi Venkataramana.  (2013-07-05)  A validated stability-indicating UPLC method for the determination of impurities in Maraviroc..  Journal of chromatographic science,  52  ((7)):  (609-616).  [PMID:23825352]
108. Mirlinda Biba,Christopher J Welch,Joe P Foley.  (2014-04-15)  Investigation of a new core-shell particle column for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides..  Journal of pharmaceutical and biomedical analysis,  96  ():  (54-57).  [PMID:24727281]
109. Long-Ze Lin,Jianghao Sun,Pei Chen,Maria J Monagas,James M Harnly.  (2014-07-18)  UHPLC-PDA-ESI/HRMSn profiling method to identify and quantify oligomeric proanthocyanidins in plant products..  Journal of agricultural and food chemistry,  62  ((39)):  (9387-9400).  [PMID:25032782]
110. Xiao Li,Jie Tan,Jiekai Yu,Jiandong Feng,Aiwu Pan,Shu Zheng,Jianmin Wu.  (2014-10-11)  Use of a porous silicon-gold plasmonic nanostructure to enhance serum peptide signals in MALDI-TOF analysis..  Analytica chimica acta,  849  ():  (27-35).  [PMID:25300214]
111. Jin Li,Qiu-hong Zhang,Jun He,Er-wei Liu,Xiu-mei Gao,Yan-xu Chang.  (2015-06-17)  An Improved LC-MS/MS Method for Simultaneous Determination of the Eleven Bioactive Constituents for Quality Control of Radix Angelicae Pubescentis and Its Related Preparations..  TheScientificWorldJournal,  2015  ():  (365093-365093).  [PMID:26078992]
112. Hua Wei, Jian Liu, Xin Wang , Zihan Li , Lijuan Ju , Boxuan Yao, Jiarui Zhou, Lei Zhao, Mingyang Zhou, Jie Zhang , Shenghong Yang.  (2023)  Secondary metal doped cuprous-cyanoimidazole frameworks for triple-mode detection of dopamine .  Secondary metal doped cuprous-cyanoimidazole frameworks for triple-mode detection of dopamine ,  1279  (-):  (341798).  [PMID:]